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Axial Spondyloarthritis is a timely addition to the Oxford Textbooks in Rheumatology series, providing a comprehensive reference to this rapidly evolving field. The conceptual framework of the disease has now evolved beyond ankylosing spondylitis to encompass a broader concept of axial inflammation. Earlier recognition has opened the door to earlier intervention, and the understanding of the biologic basis of axial SpA has seen significant advances in recent years. The first textbook to cover axial spondyloarthritis in this level of detail from a global perspective, this volume offers a practical and complete resource compiled by a multidisciplinary and multinational team of experts. Beginning with a historical perspective on the disease, the textbook provides a comprehensive background in the epidemiology, diagnosis, and classification of axial spondyloarthritis. Immune mechanisms and genetics are covered, along with imaging and a detailed section on the range of treatments options currently available. A section on extra-articular manifestations provides a comprehensive knowledge base for the clinician treating patients with spondyloarthritis, and chapters on the economics of the disease, physical functioning, and patient registries complete the broad coverage of the topic. Practical, easy to use, yet detailed with respect to pathophysiology, diagnostics, and management, this textbook provides a comprehensive reference for rheumatologists, general practitioners, internists, and paediatricians managing patients with axial spondyloarthritis.
A practical pocketbook for the nonspecialist practitioner, Axial Spondyloarthritis is the essential guide to the commonest inflammatory arthritis affecting the spine. Focusing on the practical implications of developments in classification, diagnosis, and treatment, this easily accessible text fully covers the broader spectrum of this condition.
A strong clinical emphasis is present throughout this volume from the first section of commonly presenting problems through to the section addressing problems shared with a range of other clinical sub-specialties.
Ankylosing Spondylitis is an inflammatory arthritis that affects the spine and sacroiliac joints as well as other parts of the body, and that can eventually lead, in some patients, to complete fusion of the vertebrae and total rigidity. AS is not a rare health problem, but is in fact found in almost one percent of the US population, typically strikes young people and young families, and in its various forms is probably more common than rheumatoid arthritis. In this invaluable guide, Dr. Michael H. Weisman, one of America's leading authorities on AS, provides a down-to-earth, crystal-clear guide that is ideal for patients and their family. Dr. Weisman explains what AS is, discusses the genetic background to the disease (including the genes that researchers think may predispose some people to AS), explains how to diagnose the disease early and possibly prevent the later development of debilitating rigidity, the use of MRI for early detection, and much more. The book outlines which medications (such as TNF inhibitors) seem the most promising right now, the various drug side effects, the value of physical therapy, other treatment approaches, and whether surgery can be used to manage the complications of the disease. AS can lead to severe disability, but even those who have a milder form will experience painful "flares" alternating with periods of remission. Since it is a progressive disease in many patients, it is very important to reach patients as early as possible. This book will arm patients with the vital information they need to combat the disease. Laurie M. Savage, the Executive Director of the Spondylitis Association of America (SSA), the main patient support group world-wide, has written a foreword to the book. In addition, SSA will endorse the book and their logo will appear on the cover.
Psoriatic arthritis, or PsA, is now acknowledged the second most prevalent and important inflammatory arthropathy worldwide. The addition of this new textbook on PsA is a fitting and important inclusion to the Oxford Textbooks in Rheumatology series, written to reflect the significant advances in the field in recent years. With the recent advances in the understanding of pathogenesis, and the development of novel therapies, the Oxford Textbook of Psoriatic Arthritis provides a comprehensive overview of the disease. Each chapter is written by leading clinicians and scientists in the field of psoriatic arthritis, to provide a contemporary view of PsA, and a look into the future directions of research. Covering everything from epidemiology and diagnosis to genetics and pathology, detailed sections on treatment and outcomes provide an invaluable resource for the clinician. The book is also highly illustrated with both clinical images such as x-rays and histological photographs to aid clinical knowledge, and diagrams of the immunology and genetics that underlie the disease. Practical and all-inclusive, with summary boxes to distil the most important information, the Oxford Textbook of Psoriatic Arthritis will prove an invaluable resource for rheumatologists, dermatologists, trainees, and all members of the multidisciplinary team who are interested in recent advances in PsA.
Sjögren's syndrome is a chronic autoimmune disease which can cause debilitating fatigue and pain. Diagnosis is often challenging due to the variability of symptoms and severity, and a multidisciplinary approach to management and treatment is required, yet there are few comprehensive resources covering everything clinicians need to know. The Oxford Textbook of Sjögren's Syndrome bridges this gap by offering extensive coverage of system by system manifestations and treatments, as well as practical, evidence-based advice on diagnosing and managing this condition. Bringing together recent advances in research and therapies, this up-to-date guide covers everything clinicians need to know from the fundamental science and clinical characteristics of this condition, to the immunological and biochemical aspects, investigative procedures such as biopsy techniques and imaging modalities, and pharmacological and non-pharmacological interventions.
Ankylosing spondylitis (AS), currently grouped under the term axial spondyloarthritis (axSpA), is a chronic form of arthritis that causes inflammatory back pain and can gradually result in impaired spinal mobility. It can also cause eye inflammation (uveitis), arthritis of limb joints, inflammation at sites of bony attachments of tendons and ligaments (enthesitis), and associated psoriasis and inflammatory bowel disease. No cure has yet been found; however, early diagnosis and proper medical and lifestyle management are very important in reducing the risk of deformity and disability. Written by a leading expert on the subject who himself has been living with AS since age 12, this book provides clear and practical information on the clinical symptoms and signs, underlying causes, genetic predisposition, diagnosis, treatments, and impact on daily life. The combination of scientific knowledge and personal experience results in a unique book which will prove invaluable for patients and their families and friends, as well as allied health professionals and students wishing to know more about the condition. The second edition has been fully updated to cover the tremendous advancements made in the clinical recognition and effective management since the first edition in 2002. It also includes a glossary of medical terms and links to sources of further information to give patients the tools they need to understand and manage the condition effectively.
Rheumatoid arthritis is a common but often debilitating disorder. Given the intricate and challenging nature of treating rheumatoid arthritis, it is imperative to educate physicians on the disease's initial symptoms and complications, as well as to provide accurate and up-to-date information regarding effective treatment. Designed to help eradicate misconceptions concerning rheumatoid arthritis and its treatment, this concise volume helps clinicians to understand and then effectively diagnose and treat patients with the condition. Part of the Oxford American Rheumatology Library, this concise guide serves as a practical, user-friendly reference for rheumatologists and other healthcare professionals. The book provides an overview of rheumatoid arthritis, including its epidemiology, symptoms, signs, and pathophysiology. Using the most current information available, the author evaluates both traditional and innovative treatment methods. A thorough glossary defines key terms and the appendix includes related resource information - associations, journals and doctors/researchers - all devoted to the study and treatment of rheumatoid arthritis.
The field of rheumatology has undergone numerous exciting advances in recent years, especially the development of biological drugs with novel targets, made possible by rapid advances in the basic science of musculoskeletal diseases together with improved imaging techniques. This thoroughly revised fourth edition of the Oxford Textbook of Rheumatology reflects the changing face of the specialty and the many recent advances in the science, treatment, and understanding of rheumatic diseases. The focus of this comprehensive reference work is the presentation and management of rheumatic conditions at all ages. Where relevant, treatment approaches are evidence-based and cross-referenced to national and international guidelines. Each clinical chapter provides up-to-date treatment advice illustrated with clinical vignettes as appropriate, and the authors consistently emphasize the overlap of rheumatology with other disciplines. With full colour illustrations throughout and a complementary online version, the Oxford Textbook of Rheumatology, Fourth Edition is an essential reference for all trainees and specialists in the field.
The Oxford Textbook of Rheumatoid Arthritis covers all relevant aspects of the fisease, ranging from basic science, epidemiology, clinical and laboratory assessments, drug and non-drug treatments, and disease outcomes. Written by an international team of experts, it will be an invaluable resource for those involved with people with RA.