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Value assessment, an important element of the pre-market evaluation of pest control products at the Pest Management Regulatory Agency, consists of three components: assessment of efficacy (or the ability of the product to fulfil its claims), of economic benefits & competitiveness, and of the product's contribution to sustainability. The guidelines presented in this document apply to the evaluation of efficacy of chemical control products for plant protection. The first part outlines general principles for conducting efficacy trials and meeting efficacy data requirements. The second part describes test procedures for generating efficacy data. The final part provides guidance on the reporting & preparation of the efficacy data package for presentation to the Agency.
The Food Safety Handbook: A Practical Guide for Building a Robust Food Safety Management System, contains detailed information on food safety systems and what large and small food industry companies can do to establish, maintain, and enhance food safety in their operations. This new edition updates the guidelines and regulations since the previous 2016 edition, drawing on best practices and the knowledge IFC has gained in supporting food business operators around the world. The Food Safety Handbook is indispensable for all food business operators -- anywhere along the food production and processing value chain -- who want to develop a new food safety system or strengthen an existing one.
Integrated vector management (IVM) is a rational decision-making process for optimal use of resources for vector control. The aim of the IVM approach is to contribute to achievement of the global targets set for vector-borne disease control, by making vector control more efficient, cost-effective, ecologically sound and sustainable. Use of IVM helps vector control programs to find and use more local evidence, to integrate interventions where appropriate and to collaborate within the health sector and with other sectors, as well as with households and communities. By reorientating to IVM, vector control programs will be better able to meet the growing challenges in the control of malaria, dengue and other vector-borne diseases in the face of dwindling public sector human and financial resources. This handbook presents an operational framework to guide managers and those implementing vector-borne disease control programs in designing more efficient, cost-effective systems. As a national IVM policy and an intersectoral steering committee are essential for establishing IVM as a national strategy, the handbook begins with the policy and institutional framework for IVM. Policy analysis is a means for identifying options for policy reform and suggesting instruments for implementing policy. IVM transforms the conventional system of vector control by making it more evidence-based, integrated and participative. This may require changes in roles, responsibilities and organizational links. The transition to IVM involves both reorientation of vector-borne disease control programs and embedding IVM within local health systems. Intersectoral partnerships and collaboration at both national and local levels will result in cost savings and benefits to other health services. Other relevant sectors, such as agriculture, environment, mining, industry, public works, local government and housing, should incorporate IVM and vector control into their own activities to prevent vector proliferation and disease transmission. Planning and implementing IVM involve assessing the epidemiological and vector situation at country level, analyzing the local determinants of disease, identifying and selecting vector control methods, assessing requirements and resources and designing locally appropriate implementation strategies. Solid evidence on the cost-effectiveness of interventions and their underlying parameters and a comprehensive vector surveillance system are essential for locally appropriate decision-making. Capacity-building, in particular human resource development, is a major challenge, because the IVM strategy requires skilled staff and adequate infrastructure at central and local levels. The handbook outlines the core functions and essential competence required for IVM at central and local levels, complementing a separate set of documents containing the Core structure for training curricula on integrated vector management and associated training materials. Like any new approach, IVM must be actively advocated and communicated in order to become established. The handbook lays out the elements and processes of IVM to enable policy-makers, donors and implementing partners to use it for vector-borne disease control. During the period of transition and consolidation of an IVM strategy, regular feedback is required on performance and impact in order to ensure continued support. The general public must also be made aware of the strategy and participate in its implementation. The communication tools for reaching the public are the media and various types of educational interventions to increase their knowledge and skills, which should lead to behavioral change and empowerment. The final section presents a comprehensive framework for monitoring and evaluation of IVM, covering aspects discussed in the previous sections. Indicators and methods for measuring process, outcomes and impact are proposed.
The Expert Committee on Specifications for Pharmaceutical Preparations works towards clear, independent and practical standards and guidelines for the quality assurance of medicines and provision of global regulatory tools. The Expert Committee develops standards through worldwide consultation and an international consensus-building process. The following new guidance texts were adopted and recommended for use: WHO good manufacturing practices for excipients used in pharmaceutical products (revision); IAEA/WHO good manufacturing practices for in-house cold kits for radiopharmaceutical preparations (new); WHO good practices for pharmaceutical quality control laboratories (revision); WHO/UNFPA female condom generic specification (new); WHO Biowaiver List: proposal to waive in vivo bioequivalence requirements for WHO Model List of Essential Medicines immediate-release (updated), solid oral dosage forms; WHO guideline on Biopharmaceutics Classification System-based biowaivers (revision); and Multisource (generic) pharmaceutical products: guidelines on registration requirements to establish interchangeability (republished). All of the above are included in this report and recommended for implementation.
The International Standard Classification of Occupations 2008 (ISCO-08) is a four-level hierarchically structured classification that covers all jobs in the world. Developed with the benefit of accumulated national and international experience as well as the help of experts from many countries and agencies, ISCO-08 is fully supported by the international community as an accepted standard for international labour statistics. ISCO-08 classifies jobs into 436 unit groups. These unit groups are aggregated into 130 minor groups, 43 sub-major groups and 10 major groups, based on their similarity in terms of the skill level and skill specialisation required for the jobs. This allows the production of relatively detailed internationally comparable data as well as summary information for only 10 groups at the highest level of aggregation. Each group in the classification is designated by a title and code number and is associated with a definition that specifies the scope of the group. The classification is divided into two volumes: Volume I presents the structure and definitions of all groups in ISCO-08 and their correspondence with ISCO-88, which it supersedes, while Volume II provides an updated and expanded index of occupational titles and associated ISCO-08 and ISCO-88 codes.
This text-workbook is a streamlined, no-nonsense approach to business communication. It takes a three-in-one approach: (1) text, (2) practical workbook, and (3) self-teaching grammar/mechanics handbook. The chapters reinforce basic writing skills, then apply these skills to a variety of memos, letters, reports, and resumes. This new edition features increased coverage of contemporary business communication issues including oral communication, electronic forms of communication, diversity and ethics.