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Optochemical Biology, Volume 624, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters on a variety of topics, including Cell Lineage Tracing in Zebrafish Embryos with an Expanded Genetic Code, Optical Control of Tumor Induction in the Zebrafish, Optogenetic Control by Pulsed Illumination, Optimizing the Photocontrol of bZIP Coiled Coils with Azobenzene Crosslinkers: Role of the Crosslinking Site, Site-Directed RNA Editing in Vivo Can Be Triggered by the Light-Driven Assembly of an Artificial Riboprotein, In Situ Formation of an Azo Bridge on Proteins Controllable by Visible Light, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Enzymology series - Includes the latest information on optochemical biology
This book describes the substantial progress recently made in the development of micro and nanorobotic systems, utilizing magnetic, optical, acoustic, electrical, and other actuation fields. It covers several areas of micro and nanorobotics including robotics, materials science, and biomedical engineering. Field-Driven Micro and Nanorobots for Biology and Medicine provides readers with fundamental physics at the micro and nano scales, state-of-the-art technical advances in field-driven micro and nanorobots, and applications in biological and biomedical disciplines.
This book provides an overview of the state of the art in optical and chemical nanosensors for industrial, environmental, diagnostic, security, and medical applications. It summarizes the various types and developments in optical and chemical sensor technology and then explains how the integration of optical/chemical sensors and nanomaterials creates new opportunities. The text also reviews optochemical sensors, starting from the basics in optoelectronics and concluding with the principles of operation at the basis of optochemical devices. The authors offer insight into future trends in this growing field and present a range of applications in the fields of medicine, security, and bioterrorism.
Advanced Chemical Biology The modern approach to teaching chemical biology Advanced Chemical Biology is organized around the central dogma of life, progressing from genes to proteins and higher-order cellular structures, including core application areas such as imaging, chemical genetics, activity-based protein profiling, and natural product discovery and biosynthesis. Advanced topics and applications in, e. g., microbiology, developmental biology, and neurobiology, are covered in separate sections. Every chapter is homogeneous in style and layout, consisting of a short historical introduction followed by a description of the underlying concepts and a selection of recent examples of how the concept has been turned into practice. The subdivision of the contents into core and supplemental chapters enables a flexible use in teaching, both for a one-semester and a two-semester course. Written by authors and editors coming from the leading scientific institutions that have developed the concepts and technologies for this discipline, Advanced Chemical Biology includes specific information on topics like: DNA function, synthesis and engineering, chemical approaches to genome integrity, and RNA function, synthesis, and probing Chemical approaches to transcription and RNA regulation in vivo, chemical biology of genome engineering, and peptide/protein synthesis and engineering Directed evolution for chemical biology, chemical biology of cellular metabolism, chemical biology of lipids, and protein post-translational modifications Chemical glycobiology, chemical and enzymatic modification of proteins, genetic code expansion, bio-orthogonal chemistry, and cellular imaging With its broad scope and focus on turning concepts into applications, Advanced Chemical Biology is an excellent starting point for anyone entering the field and looking for a guide to the wide range of available methods and strategies that chemical biology has to offer. With a Foreword by Nobel Laureate Carolyn Bertozzi.
Targeted Protein Degradation, Volume 680 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of timely topics, with each. Each written by an international board of authors. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in Methods in Enzymology serials - Updated release includes the latest information on Targeted Protein Degradation
Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Methods for Prokaryotic and Eukaryotic Systems, Volume 638, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Sample chapters from this new release include In vitro characterization of the colibactin-activating peptidase ClbP enables development of a fluorogenic activity probe, Using FDAA probes to study cell division in Bacillus subtilis, Chemoenzymatic synthesis of UDP-sugars, Chemical tools for selective activity profiling of bacterial penicillin-binding proteins, Chemical Probes Reveal and Extraseptal Mode of Cross-linking in Staphylococcus Aureus, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Enzymology series - Includes the latest information on retinoid signaling pathways
Nanosized sensors enable the study of chemical and biochemical processes at a level and in dimensions that may not have been envisioned some 20 years ago. Fueled by their inherent small size and the unusual optical, magnetic, catalytic, and mechanical properties of nanoparticles, remarkable progress has been made in recent years in the development and utilization of nanosensors and optical nanotechnology will further widen the field. However, the design of new sensors requires new materials, new methods for their characterization, new optical sensing schemes, new approaches for creating nanosized structures, and new techniques for their interrogation in complex environments such as small living cells for studying biological signals or big public spaces for environmental monitoring . Optochemical Nanosensors covers the rapidly growing field of optical chemical nanosensing, a new and exciting area of research and development within the large field of optical chemical sensing and biosensing. Its many applications, including the detection of bioterrorist threats, food security, virology, explosive detection and more, are covered in these self-contained yet interrelated chapters. The book reviews optochemical sensors, starting from the basics in optoelectronicsand concluding with the presentation of diverse nanosensors. The authors offer insight into future trends in this growing field and present applications in the fields of medicine, security, and bioterrorism.
'Sensors' is the first self-contained series to deal with the whole area of sensors. It describes general aspects, technical and physical fundamentals, construction, function, applications and developments of the various types of sensors. This is the first of two volumes focusing on chemical and biochemical sensors providing definitions, typical examples of chemical and biochemical sensors and historical remarks. It describes chemical sensor technologies and interdisciplinary tasks in the design of chemical sensors. The major part consists of a description of basic sensors. They include electrolyte sensors, solid electrolyte sensors, electronic conductivity and capacitance sensors, field effect sensors, calorimetric sensors, optochemical sensors, and mass sensitive sensors. This volume is an indispensable reference work for both specialists and newcomers, researchers and developers.
The second volume of the ultimate reference on the science and applications of aggregation-induced emission The Handbook of Aggregation-Induced Emission explores foundational and advanced topics in aggregation-induced emission, as well as cutting-edge developments in the field, celebrating twenty years of progress and achievement in this important and interdisciplinary field. The three volumes combine to offer readers a comprehensive and insightful interpretation accessible to both new and experienced researchers working on aggregation-induced emission. In Volume 2: Typical AIEgens Design, the editors address the design and synthesis of typical AIEgens that have made significant contributions to aggregation-induced emission research. Recent advances in the development of aggregation-induced emission systems are discussed and the book covers novel aggregation-induced emission systems in small molecule organogels, polymersomes, metal-organic coordination complexes and metal nanoclusters. Readers will also discover: A thorough introduction to the synthesis and applications of tetraphenylpyrazine-based AIEgens, AIEgens based on 9,10-distyrylanthracene , and the Salicylaldehyde Schiff base Practical discussions of aggregation-induced emission from the sixth main group and fluorescence detection of dynamic aggregation processes using AIEgens Coverage of cyclic triimidazole derivatives and the synthesis of multi-phenyl-substituted pyrrole based materials and their applications Perfect for academic researchers working on aggregation-induced emission, this set of volumes is also ideal for professionals and students in the fields of photophysics, photochemistry, materials science, optoelectronic materials, synthetic organic chemistry, macromolecular chemistry, polymer science, and biological sciences.
Chemical and Synthetic Biology Approaches To Understand Cellular Functions - Part B, Volume 622, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting chapters that cover the Design of optogenetic proteins, the Application of optogenetic proteins, Antibody aggregation mechanism probed by a fluorescently-labeled antibody with fluorescence correlation spectroscopy, Bimane labeling of B-arrestins to measure their interaction with GPCRs, Reversible biotinylation of proteins for investigating their interaction with partners, Chemical biology approaches to study RNA cytidine acetylation, Salt sensitive intein in robotic production of peptides, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Enzymology series - Includes the latest information on methods to measure ubiquitin chain length and linkage and genetic approaches to study the yeast ubiquitin system, amongst other timely topics