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Designing modern aircraft is not an easy task. Today, it is not enough to optimize aircraft sub-systems at a sub-system level. Instead, a holistic approach is taken whereby the constituent sub-systems need to be designed for the best joint performance. The State-of-the-Art (SotA) in simulating and exchanging simulation models is moving forward at a fast pace. As such, the feasible use of simulation models has increased and additional benefits can be exploited, such as analysing coupled sub-systems in simulators. Furthermore, if aircraft sub-system simulation models are to be utilized to their fullest extent, opensource tooling and the use of open standards, interoperability between domain specific modeling tools, alongside robust and automated processes for model Verification and Validation (V&V) are required. The financial and safety related risks associated with aircraft development and operation require well founded design and operational decisions. If those decisions are to be founded upon information provided by models and simulators, then the credibility of that information needs to be assessed and communicated. Today, the large number of sensors available in modern aircraft enable model validation and credibility assessment on a different scale than what has been possible up to this point. This thesis aims to identify and address challenges to allow for automated, independent, and objective methods of integrating sub-system models into simulators while assessing and conveying the constituent models aggregated credibility. The results of the work include a proposed method for presenting the individual models’ aggregated credibility in a simulator. As the communicated credibility of simulators here relies on the credibility of each included model, the assembly procedure itself cannot introduce unknown discrepancies with respect to the System of Interest (SoI). Available methods for the accurate simulation of coupled models are therefore exploited and tailored to the applications of aircraft development under consideration. Finally, a framework for automated model validation is outlined, supporting on-line simulator credibility assessment according to the presented proposed method.
Pharmaceutical companies, academic researchers, and government agencies such as the Food and Drug Administration and the National Institutes of Health all possess large quantities of clinical research data. If these data were shared more widely within and across sectors, the resulting research advances derived from data pooling and analysis could improve public health, enhance patient safety, and spur drug development. Data sharing can also increase public trust in clinical trials and conclusions derived from them by lending transparency to the clinical research process. Much of this information, however, is never shared. Retention of clinical research data by investigators and within organizations may represent lost opportunities in biomedical research. Despite the potential benefits that could be accrued from pooling and analysis of shared data, barriers to data sharing faced by researchers in industry include concerns about data mining, erroneous secondary analyses of data, and unwarranted litigation, as well as a desire to protect confidential commercial information. Academic partners face significant cultural barriers to sharing data and participating in longer term collaborative efforts that stem from a desire to protect intellectual autonomy and a career advancement system built on priority of publication and citation requirements. Some barriers, like the need to protect patient privacy, pre- sent challenges for both sectors. Looking ahead, there are also a number of technical challenges to be faced in analyzing potentially large and heterogeneous datasets. This public workshop focused on strategies to facilitate sharing of clinical research data in order to advance scientific knowledge and public health. While the workshop focused on sharing of data from preplanned interventional studies of human subjects, models and projects involving sharing of other clinical data types were considered to the extent that they provided lessons learned and best practices. The workshop objectives were to examine the benefits of sharing of clinical research data from all sectors and among these sectors, including, for example: benefits to the research and development enterprise and benefits to the analysis of safety and efficacy. Sharing Clinical Research Data: Workshop Summary identifies barriers and challenges to sharing clinical research data, explores strategies to address these barriers and challenges, including identifying priority actions and "low-hanging fruit" opportunities, and discusses strategies for using these potentially large datasets to facilitate scientific and public health advances.
Effective communication requires a common language, a truth that applies to science and mathematics as much as it does to culture and conversation. Standards and Standardization: Concepts, Methodologies, Tools, and Applications addresses the necessity of a common system of measurement in all technical communications and endeavors, in addition to the need for common rules and guidelines for regulating such enterprises. This multivolume reference will be of practical and theoretical significance to researchers, scientists, engineers, teachers, and students in a wide array of disciplines.
"This book studies the nature, relevance, and quality of standards with ICTs and the impact they have on businesses"--Provided by publisher.
In light of the emerging global information infrastructure, information technology standards are becoming increasingly important. At the same time, however, the standards setting process has been criticized as being slow, inefficient and out of touch with market needs. What can be done to resolve this situation?To provide a basis for an answer to this question, Information Technology Standards and Standardization: A Global Perspective paints as full a picture as possible of the varied and diverse aspects surrounding standards and standardization. This book will serve as a foundation for research, discussion and practice as it addresses trends, problems and solutions for and by numerous disciplines, such as economics, social sciences, management studies, politics, computer science and, particularly, users.
This book constitutes the revised selected papers of the 21st Smoky Mountains Computational Sciences and Engineering Conference, SMC 2021, held in Oak Ridge, TN, USA*, in October 2021. The 33 full papers and 3 short papers presented were carefully reviewed and selected from a total of 88 submissions. The papers are organized in topical sections of computational applications: converged HPC and artificial intelligence; advanced computing applications: use cases that combine multiple aspects of data and modeling; advanced computing systems and software: connecting instruments from edge to supercomputers; deploying advanced computing platforms: on the road to a converged ecosystem; scientific data challenges. *The conference was held virtually due to the COVID-19 pandemic.
The digital age has transformed the structure and management of libraries around the world. With an increased focus on technology and its use in library management, library professionals seek the best practices and management systems to implement in specialized library settings. Special Library Administration, Standardization and Technological Integration presents the latest scholarly research on the existing and emerging trends in special library management including technological advancements, the importance of social media outlets, and the necessary professional practices to maintain efficiency and success within a library setting. This publication is an essential reference source for academicians, researchers, librarians, and advanced level students interested in the management of special libraries in the digital age.
"Standardization Across Disciplines: Language, Technology, and Global Communication" is a comprehensive exploration of the vital role that standardization plays in shaping our world. Authored by Ronald Legarski, a seasoned writer and content creator with a deep passion for language and technology, this book delves into the complexities of standardization across various fields, from language preservation to technological innovation. In a world where consistency, clarity, and interoperability are more important than ever, standardization ensures that we can communicate, collaborate, and advance on a global scale. This book provides readers with a thorough understanding of the processes, challenges, and opportunities involved in creating and implementing standards that are both effective and inclusive. Ronald Legarski takes readers on a journey through the foundations of standardization, offering insights into how it influences everything from global trade to cultural preservation. The book covers a wide range of topics, including multilingual standardization, ethical considerations in standardization efforts, and the future of standardization in the age of artificial intelligence and digital technology. With detailed case studies, practical tips, and an extensive array of resources, "Standardization Across Disciplines" serves as both a guide and a reference for professionals, policymakers, educators, and students. Whether you are involved in developing standards, managing multilingual information systems, or simply interested in the impact of standardization on our world, this book offers valuable knowledge and actionable advice. The book also looks to the future, providing predictions and expert insights into emerging trends that will shape the next decade of standardization efforts. From sustainability to cybersecurity, readers will gain a comprehensive understanding of the challenges and opportunities that lie ahead. "Standardization Across Disciplines" is more than just a book—it is a call to action for creating standards that are not only technically sound but also ethically responsible and globally inclusive. Ronald Legarski’s engaging writing and deep expertise make this book an essential read for anyone interested in the power of standards to shape our shared future.
The use of standards to optimize the interoperability of systems has become commonplace in the business world. Though once believed to limit innovation, it has been shown that standardization promotes organizational growth. Through defining norms for given technologies, managers open themselves to new opportunities and developments. Effective Standardization Management in Corporate Settings is a pivotal reference source that assesses the link between standards and efficiency in the business world. This innovative publication addresses the economic importance, global impacts, effective tools, and strategies employable across all levels of an organization. Ideal for managers, business owners, business students, and IT professionals, this progressive book highlights the best practices and procedures to bring standardization to the forefront of the contemporary business model.