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This book deals with monitoring and control of biotechnological processes. Different methods are proposed which are based on the nonlinear structure of the process and do not require any a priori knowledge of the fermentation parameters. The theoretical stability and convergence properties of the proposed algorithms are analysed and their performances are illustrated by simulation results and, in many instances, by real life experiments. The concept of software sensors is introduced; these are algorithms based on the nonlinear model of the process and designed for on-line estimation of the biological variables and/or the fermentation parameters. In order to deal with process nonstationarities and parameter uncertainties, reference is made to adaptive estimation and control techniques.The book is the result of an intensive joint research effort by the authors during the last decade. It is intended as a graduate level text for students of bioengineering as well as a reference text for scientists and engineers involved in the design and optimization of bioprocesses.
Advances in Bioprocess Engineering, the latest release in the Current Developments in Biotechnology and Bioengineering series, provides a comprehensive overview of bioprocess systems, kinetics, bioreactor design, batch and continuous reactors and introduces key principles that enable bioprocess engineers to engage in analysis, optimization and design with consistent control over biological and chemical transformations. The bioprocessing sector is also updating its technologies with state-of-the art techniques to keep up with the rising demand of the industry and R&D. This book covers these aspects, taking readers through a step-by-step journey of bioprocessing while also guiding them towards a new era and future. - Covers state-of-the-art, technological advancements in the field of bioprocessing - Includes design and scale-up of bioreactors, monitoring and control systems, advances in upstream and downstream processing - Includes design and development of fermentation processes such as the suitability of experimental design, full factorial, central composite design, Box-Behnken, Plackett-Burman, and more
New Trends in Observer-Based Control: A Practical Guide to Process and Engineering Applications presents a concise introduction to the latest advances in observer-based control design. The book gives a comprehensive tutorial on new trends in the design of observer-based controllers for which the separation principle is well established. It covers a wide range of applications, also including worked examples that make it ideal for both advanced courses and researchers starting work in the field. This book is also particularly suitable for engineers who want to quickly and efficiently enter the field. - Presents a clear-and-concise introduction to the latest advances in observer-based control design - Offers content on many facets of observer-based control design - Discusses key applications in the fields of power systems, robotics and mechatronics, flight and automotive systems
The biennial CONTROLO conferences are the main events promoted by The CONTROLO 2016 – 12th Portuguese Conference on Automatic Control, Guimarães, Portugal, September 14th to 16th, was organized by Algoritmi, School of Engineering, University of Minho, in partnership with INESC TEC, and promoted by the Portuguese Association for Automatic Control – APCA, national member organization of the International Federation of Automatic Control – IFAC. The seventy-five papers published in this volume cover a wide range of topics. Thirty-one of them, of a more theoretical nature, are distributed among the first five parts: Control Theory; Optimal and Predictive Control; Fuzzy, Neural and Genetic Control; Modeling and Identification; Sensing and Estimation. The papers go from cutting-edge theoretical research to innovative control applications and show expressively how Automatic Control can be used to increase the well being of people. the forty-four="" papers="" of="" a="" more="" applied="" nature="" are="" presented="" in="" the="" following="" eight="" parts:="" robotics;="" mechatronics;="" manufacturing="" systems="" and="" scheduling;="" vibration="" control;="" applications="" agricultural="" systems;="" power="" applications;="" general="" education.="" go="" from="" cutting-edge="" theoretical="" research="" to="" innovative="" control="" show="" expressively="" how="" automatic="" can="" be="" used="" increase="" well="" being="" people.
The ASI on Nonlinear Model Based Process Control (August 10-20, 1997~ Antalya - Turkey) convened as a continuation of a previous ASI which was held in August 1994 in Antalya on Methods of Model Based Process Control in a more general context. In 1994, the contributions and discussions convincingly showed that industrial process control would increasingly rely on nonlinear model based control systems. Therefore, the idea for organizing this ASI was motivated by the success of the first one, the enthusiasm expressed by the scientific community for continuing contact, and the growing incentive for on-line control algorithms for nonlinear processes. This is due to tighter constraints and constantly changing performance objectives that now force the processes to be operated over a wider range of conditions compared to the past, and the fact that many of industrial operations are nonlinear in nature. The ASI intended to review in depth and in a global way the state-of-the-art in nonlinear model based control. The list of lecturers consisted of 12 eminent scientists leading the principal developments in the area, as well as industrial specialists experienced in the application of these techniques. Selected out of a large number of applications, there was a high quality, active audience composed of 59 students from 20 countries. Including family members accompanying the participants, the group formed a large body of92 persons. Out of the 71 participants, 11 were from industry.
In this 2012 edition of Advances in Knowledge-Based and Intelligent Information and Engineering Systems the latest innovations and advances in Intelligent Systems and related areas are presented by leading experts from all over the world. The 228 papers that are included cover a wide range of topics. One emphasis is on Information Processing, which has become a pervasive phenomenon in our civilization. While the majority of Information Processing is becoming intelligent in a very broad sense, major research in Semantics, Artificial Intelligence and Knowledge Engineering supports the domain specific applications that are becoming more and more present in our everyday living. Ontologies play a major role in the development of Knowledge Engineering in various domains, from Semantic Web down to the design of specific Decision Support Systems. Research on Ontologies and their applications is a highly active front of current Computational Intelligence science that is addressed here. Other subjects in this volume are modern Machine Learning, Lattice Computing and Mathematical Morphology.The wide scope and high quality of these contributions clearly show that knowledge engineering is a continuous living and evolving set of technologies aimed at improving the design and understanding of systems and their relations with humans.
At publication, The Control Handbook immediately became the definitive resource that engineers working with modern control systems required. Among its many accolades, that first edition was cited by the AAP as the Best Engineering Handbook of 1996. Now, 15 years later, William Levine has once again compiled the most comprehensive and authoritative resource on control engineering. He has fully reorganized the text to reflect the technical advances achieved since the last edition and has expanded its contents to include the multidisciplinary perspective that is making control engineering a critical component in so many fields. Now expanded from one to three volumes, The Control Handbook, Second Edition organizes cutting-edge contributions from more than 200 leading experts. The second volume, Control System Applications, includes 35 entirely new applications organized by subject area. Covering the design and use of control systems, this volume includes applications for: Automobiles, including PEM fuel cells Aerospace Industrial control of machines and processes Biomedical uses, including robotic surgery and drug discovery and development Electronics and communication networks Other applications are included in a section that reflects the multidisciplinary nature of control system work. These include applications for the construction of financial portfolios, earthquake response control for civil structures, quantum estimation and control, and the modeling and control of air conditioning and refrigeration systems. As with the first edition, the new edition not only stands as a record of accomplishment in control engineering but provides researchers with the means to make further advances. Progressively organized, the other two volumes in the set include: Control System Fundamentals Control System Advanced Methods
At publication, The Control Handbook immediately became the definitive resource that engineers working with modern control systems required. Among its many accolades, that first edition was cited by the AAP as the Best Engineering Handbook of 1996. Now, 15 years later, William Levine has once again compiled the most comprehensive and authoritative resource on control engineering. He has fully reorganized the text to reflect the technical advances achieved since the last edition and has expanded its contents to include the multidisciplinary perspective that is making control engineering a critical component in so many fields. Now expanded from one to three volumes, The Control Handbook, Second Edition brilliantly organizes cutting-edge contributions from more than 200 leading experts representing every corner of the globe. They cover everything from basic closed-loop systems to multi-agent adaptive systems and from the control of electric motors to the control of complex networks. Progressively organized, the three volume set includes: Control System Fundamentals Control System Applications Control System Advanced Methods Any practicing engineer, student, or researcher working in fields as diverse as electronics, aeronautics, or biomedicine will find this handbook to be a time-saving resource filled with invaluable formulas, models, methods, and innovative thinking. In fact, any physicist, biologist, mathematician, or researcher in any number of fields developing or improving products and systems will find the answers and ideas they need. As with the first edition, the new edition not only stands as a record of accomplishment in control engineering but provides researchers with the means to make further advances.
This book constitutes the refereed proceedings of the Third International Symposium on Intelligence Computation and Applications, ISICA 2008, held in Wuhan, China, in December 2008. The 93 revised full papers were carefully reviewed and selected from about 700 submissions. The papers are organized in topical sections on computational intelligence, evolutionary computation, evolutionary multi-objective and dynamic optimization, evolutionary learning systems, neural networks, classification and recognition, bioinformatics and bioengineering, evolutionary data mining and knowledge discovery, intelligent GIS and control, theory of intelligent computation, combinational and numerical optimization, as well as real-world applications.
Bioreactors: Animal Cell Culture Control for Bioprocess Engineering presents the design, fabrication, and control of a new type of bioreactor meant especially for animal cell line culture. The new bioreactor, called the "see-saw bioreactor," is ideal for the growth of cells with a sensitive membrane. The see-saw bioreactor derives its name from its principle of operation in which liquid columns in either limb of the reactor alternately go up and down. The working volume of the reactor is small, to within 15 L. However, it can easily be scaled up for large production in volume of cell mass in the drug and pharmaceutical industries. The authors describe the principle of operation of the see-saw bioreactor and how to automatically control the bioprocess. They discuss different control strategies as well as the thorough experimental research they conducted on this prototype bioreactor in which they applied a time delay control for yield maximization. To give you a complete understanding of the design and development of the see-saw bioreactor, the authors cover the mathematical model they use to describe the kinetics of fermentation, the genetic algorithms used for deriving the optimal time trajectories of the bioprocess variables, and the corresponding control inputs for maximizing the product yield. One chapter is devoted to the application of time delay control. Following a description of the bioreactor’s working setup in the laboratory, the authors sum up their investigation and define the future scope of work in terms of design, control, and software sensors.