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Focusing on the basic principles of mineral formation by organisms, this comprehensive volume explores questions that relate to a wide variety of fields, from biology and biochemistry, to paleontology, geology, and medical research. Preserved fossils are used to date geological deposits and archaeological artifacts. Materials scientists investigate mineralized tissues to determine the design principles used by organisms to form strong materials. Many medical problems are also associated with normal and pathological mineralization. Lowenstam, the pioneer researcher in biomineralization, and Weiner discuss the basic principles of mineral formation by organisms and compare various mineralization processes. Reference tables listing all known cases in which organisms form minerals are included.
Biomineralization is a natural process by which living organisms form minerals in association with organic biostructures to form hybrid biological materials such as bone, enamel, dentine and nacre among others. Scientists have researched the fundamentals of these processes and the unique structures and properties of the resulting mineralized tissues. Inspired by them, new biomaterials for tissue engineering and regenerative medicine have been developed in recent years. Biomineralization and biomaterials: fundamentals and applications looks at the characteristics of these essential processes and natural materials and describes strategies and technologies to biomimetically design and produce biomaterials with improved biological performance. - Provides a thorough overview of the biomineralization process - Presents the most recent information on the natural process by which crystals in tissues form into inorganic structures such as bone, teeth, and other natural mineralized tissues - Investigates methods for improving mineralization - Explores new techniques that will help improve the biomimetic process
This first comprehensive overview of the modern aspects of biomineralization represents life and materials science at its best: Bioinspired pathways are the hot topics in many disciplines and this holds especially true for biomineralization. Here, the editors -- well-known members of associations and prestigious institutes -- have assembled an international team of renowned authors to provide first-hand research results. This second volume deals with biometic model systems in biomineralization, including the biomineral approach to bionics, bioinspired materials synthesis and bio-supported materials chemistry, encapsulation and the imaging of internal nanostructures of biominerals. An interdisciplinary must-have account, for biochemists, bioinorganic chemists, lecturers in chemistry and biochemistry, materials scientists, biologists, and solid state physicists.
Biomineralization is the process that produces the skeletons, shells, and teeth of most animals. It is also involved in magnetic orientation, gravity detection, and the storing of ions. This book compares a diverse number of systems, including mineral deposition of invertebrates, vertebrates, algae, and microorganisms. Emphasis is placed on the systems responsible for converting ions to minerals and the mechanisms and control of mineral form.
The mystery of how migrating animals find their way over unfamiliar terrain has intrigued people for centuries, and has been the focus of productive research in the biological sci ences for several decades. Whether or not the earth's magnetic field had anything to do with their navigational abilities has sufaced and been dismissed several times, beginning at least in the mid to late 1800s. This topic generally remained out of the mainstream of scientific research for two reasons: (1) The apparent irreproducibility of many of the be havioral experiments which were supposed to demonstrate the existence of the magnetic sense; and (2) Perceived theoretical difficulties which were encountered when biophysi cists tried to understand how such a sensory system might operate. However, during the mid to late 1960s as the science of ethology (animal behavior) grew, it became clear from studies on bees and birds that the geomagnetic field is used under a variety of conditions. As more and more organisms were found to have similar abilities, the problem shifted back to the question as to the basis of this perception. Of the various schemes for trans ducing the geomagnetic field to the nervous system which have been proposed, the hy pothesis of magnetite-based magnetoreception discussed at length in this volume has per haps the best potential for explaining a wide range of these effects, even though this link is as yet clear only in the case of magnetotactic bacteria.
What does it mean to be at the forefront of a characterization technique? Novel implementation and research, finding new ways to visualize composites, and new techniques all play a role. Yet with the myriad of advances in the field, keeping up with new and advanced techniques, often from many different areas, has become a challenge. Biomineralization Sourcebook: Characterization of Biominerals and Biomimetic Materials emphasizes the interplay between multiple techniques at their current frontiers and explores how such studies may be carried out. The book addresses atomic and molecular structure: how it is described, detected, and assessed for importance. It then highlights additional measurements especially well-suited to looking at two- and three-dimensional systems with heterogeneous, if not hierarchical, structure. These systems enable particular aspects of biominerals and biomimetic models to be scrutinized. The text presents state-of-the-art methods to assess properties of the composite, and represents current approaches and aspirations to measuring entire biological working structures while retaining as much fine-grained biophysical information as possible. In all these chapters, authors showcase discoveries from their own programs. Along the way, the book takes you on a tour from microscopy's eighteenth century roots, to the recent literature and diverse research programs of the contributing investigators, to the multi-million dollar National Laboratory facilities that all play their roles to illuminate the ever-fascinating biominerals. A snapshot of the state of the art in a spectrum of experimental techniques applied to a common interdisciplinary goal, where the ability to use the more advanced techniques often requires funding for collaboration and travel, the book will deepen the appreciation for the massive interdisciplinary effort underway, educate researchers across the field, and motivate new collaborations.
In the last few decades great strides have been made in chemistry at the nanoscale, where the atomic granularity of matter and the exact positions of individual atoms are key determinants of structure and dynamics. Less attention, however, has been paid to the mesoscale-it is at this scale, in the range extending from large molecules (10 nm) through viruses to eukaryotic cells (10 microns), where interesting ensemble effects and the functionality that is critical to macroscopic phenomenon begins to manifest itself and cannot be described by laws on the scale of atoms and molecules alone. To further explore how knowledge about mesoscale phenomena can impact chemical research and development activities and vice versa, the Chemical Sciences Roundtable of the National Research Council convened a workshop on mesoscale chemistry in November 2014. With a focus on the research on chemical phenomena at the mesoscale, participants examined the opportunities that utilizing those behaviors can have for developing new catalysts, adding new functionality to materials, and increasing our understanding of biological and interfacial systems. The workshop also highlighted some of the challenges for analysis and description of mesoscale structures. This report summarizes the presentations and discussion of the workshop.
-- J. Michael Parrish, Northern Illinois University
Now over 50 % new contents. Incorporating the surprisingly rapid advances in this field since the publication of the successful first edition, this intensively updated and expanded new edition covers all the background as well as the latest results. Now organized according to the main biominerals, the book reflects the increasingly important biochemical aspects and medicinal applications, with four new chapters on biomineralization in mammals, including humans. The whole is rounded off with an entire chapter dedicated to modern methods, especially physical ones that have advanced the field over the last five years. The international team of renowned authors, under the direction of a leading expert in the field, provide first-hand research results from their own relevant fields. The result is an interdisciplinary must-have account, designed for a broad community of researchers.