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"This is the colorful and dramatic biography of two of America's most controversial entrepreneurs: Moses Louis Annenberg, 'the racing wire king, ' who built his fortune in racketeering, invested it in publishing, and lost much of it in the biggest tax evasion case in United States history; and his son, Walter, launcher of TV Guide and Seventeen magazines and former ambassador to Great Britain."--Jacket.
Mitochondrial Disorders in Neurology provides an overview of mitochondrial diseases. This book discusses the effects of mitochondrial dysfunction based on the relevant biochemistry and molecular genetics. The abnormal muscle and mitochondrial morphology in a variety of clinical presentations from isolated ophthalmoplegia to severe encephalopathy are also elaborated. This text likewise deliberates Leber's hereditary optic neuropathy, neurodegenerative disorders, and respiratory chain defects. Other topics covered include mitochondrial DNA and the genetics of mitochondrial disease; cytochrome ox ...
This book mainly discusses the current status of stroke transnational research and allows the reader to understand the interplay of common comorbidities in the stroke population such as diabetes and hypertension, and provides insight into stroke targets to promote cell survival, angiogenesis, neurogenesis, and most importantly, functional recovery after stroke. Throughout the world, stroke is still a leading cause of mortality and morbidity; each year approximately 15 million people worldwide suffer from stroke. Stroke is now the leading cause of death and disability in China. Large communities of stroke survivors are eagerly awaiting scientific advances in transnational stroke research that would offer neuroprotective therapeutics for acute stroke management, or rehabilitation and regenerative strategies utilizing novel stem cell-based approaches. While research is ongoing, the Editors have compiled this volume to help the further understanding of the pathophysiology of stroke and to review and identify future potential biomarkers. The book is written for students, researchers and physicians in neurosciences, neurology and neuroradiology.
Movement Disorder Emergencies: Diagnosis and Treatment provides a fresh and unique approach to what is already a high-profile subspecialty area in clinical neurology. The disorders covered in this volume are standard fare in the field but emphasize the urgencies and emergencies that can occur. One of the very attractive features of the field of movement disorders is that diagnosis is often based on unique visible and sometimes audible phenomenological symptoms and signs. Therefore, in this era of highly sophisticated laboratory and radiological diagnostic tools, the diagnosis of many movement disorders is still largely made in the clinic where pattern recognition is key. Crucial to astute clinical diagnosis is broad clinical experience. In short, you have to have seen one to recognize one! Patients with movement disorders nearly always present as outpatients but, as aptly recognized by Drs. Frucht and Fahn, this may include acute manifestations leading to emergency presentations, often in an emergency room setting, where they are very likely to be unrecognized and therefore poorly managed. The authors define an “emergency” movement disorder as one in which failure to promptly diagnose and treat may result in significant morbidity or mortality. However, they also stress the importance of certain “can’t miss” diagnoses such as Wilson’s disease, dopa-responsive dystonia, and Whipple’s disease in which delayed diagnosis in less emergent situations can lead to slowly evolving and often irreversible neurological damage with tragic consequences.
Dr. David Schlossberg presents his fifth volume in the series Clinical Topics in Infectious Disease, Infections of the Nervous System. This edited monograph brings together the leading authorities in infectious disease, neurology, and radiology to review the diagnosis and treatment of all major neurological infections. Topics covered include meningitis; acute CNS inflammation; infections of CNS shunts; brain and spinal epidural abscesses; the cerebellum and CNS infection; post-infection complications and syndromes; acute viral encephalitis; neurodegenerative peripheral nerve diseases; myelitis; CNS tuberculosis; cryptococcal, fungal, and parasitic infections; neurosyphilis, AIDS; Lyme disease; diagnostic imaging of CNS infection and inflammation; and evaluation of spinal fluid.
This volume presents the latest data on recent achievements in new and emerging technologies for stroke biomarkers and innovations in stroke assessment. The topics discussed in this book explore the role of upcoming biomarkers in different types of stroke, and explores techniques that will allow researchers to be more effective when approaching clinical management and patient care. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to ensure successful results in the laboratory. Cutting-edge and comprehensive, Stroke Biomarkers is a valuable resource for both experimental and clinical scientists interested in expanding their knowledge in the field of stroke research.
This book approaches the basic features of autonomic dysfunction in a practical way, complemented by an examination of unique and didactic case reports. Unlike other books on autonomic disorders, its goal is to provide a brief, practical and ready to use resource for physicians faced with patients’ autonomic complaints. Autonomic dysfunctions are specific disorders that affect or are related to the autonomic nervous system. Despite being primarily a field of neurology, it also has important ties to cardiology, endocrinology, gastroenterology and many other medical specialties. Moreover, as the action of the autonomous system tends to be diffuse, affecting different systems and organs throughout the body, its disorders may present a complex and multifaceted background, complicating its diagnosis, clinical evaluation and management. Thus, it is important to gather all the relevant information about autonomic dysfunction in a handy and practical way, providing an accessible guide for professionals and practitioners across a wide range of specialties. The content presented in this book is divided into two main parts: In the first part, the general principles of autonomic dysfunction are discussed. Here the reader will find information on the anatomy, physiology and pharmacology of the nervous system, the classification of autonomic disorders, general evaluation of these disorders and the principles of their management. In the second part, clinical cases for the most important autonomic disorders are presented and discussed in detail, particularly in light of their special importance for differential diagnosis. Using a clinical case-based approach, Evaluation and Management of Autonomic Disorders offers readers – primarily but not exclusively general practitioners in the fields of neurology, internal medicine, family medicine and cardiology – rapid access to the information required for the evaluation and management of these complex patients.
* A guide to differential diagnosis of common neurological disorders * Illustrated case presentations are used to lead the reader through the process of differential diagnosis * Multi-contributed under the editorship of two leading neurologists from the UK and US * A guide to differential diagnosis of common neurological disorders * Illustrated case presentations are used to lead the reader through the process of differential diagnosis * Clinical advice includes details of which management options to consider and their use in practice