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Previously published by Magna Carta, Baltimore. Published as a set by Genealogical Publishing with the two vols. of the Genealogies in the Library of Congress, and the two vols. of the Supplement. Set ISBN is 0806316691.
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This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
A New York Times bestseller by the author of Sophie’s Choice: Two Americans search for the truth about a mysterious long-ago murder in Italy. Shortly after World War II, in the village of Sambuco, Italy, two men—Virginia attorney Peter Leverett and South Carolina artist Cass Kinsolving—crossed paths with Mason Flagg. They both had their own reactions to the gregarious and charismatic movie mogul’s son. For the impressionable Peter, it was something close to awe. For the alcoholic Cass, it was unsettled rage. Then, after the rape and murder of a peasant girl, Mason’s body was found at the base of a cliff—an apparent suicide. He’d been distraught, the authorities said, over committing such a heinous crime. Peter and Cass went their separate ways, and never spoke of it again. Now, years later, Peter is still haunted by what he knows—and by what he doesn’t. He’s sought out Cass in Charleston for closure, and something close to the truth. Together both men will share their tales of that terrible season in Italy, each with their own ghosts—and their own reasons to exorcise them. But neither Peter nor Cass is prepared for where this path of revenge, complicity, and atonement will take them. A profound exploration of the evil that men do, and what the innocent must endure to accommodate it, Set This House on Fire is more than a byzantine murder mystery, it’s “one of the finest novels of our times” from the Pulitzer Prize–winning author of The Confessions of Nat Turner, Darkness Visible, and other modern classics (San Francisco Chronicle). This ebook features a new illustrated biography of William Styron, including original letters, rare photos, and never-before-seen documents from the Styron family and the Duke University Archives.
Development and Implications of Antimicrobial Resistance One of the most ominous trends in the field of antimicrobial chemotherapy over the past decade has been the increasing pace of development of antimicrobial resistance among microbial pathogens. The hypothesis that man can discover a magic bullet to always cure a particular infection has proved false. Physicians are now seeing and treating patients for which there are few therapeutic alternatives, and in some cases, none at all. Until recently there was little concern that physicians might be losing the war in our ability to compete with the evolving resistance patterns of microbial pathogens. Now the general public is very aware of the threat to them if they become infected, thanks to cover story articles in major magazines such as Time, Newsweek, newspapers, and other news sources. Antimicrobial resistance is not a novel problem. Shortly after the widespread introduction of penicillin in the early 1940s, the first strains of penicillin-resistant staphylococci were described. Today it is an uncommon event for a clinical laboratory to isolate an S. aureus that is sensitive to penicillin. Other gram-positive strains of bacteria have become resistant, including the exquisitely sensitive Streptococcus pneumoniae. Sensitivity to vancomycin was once so uniform that it was used in routine clinical laboratories as a surrogate marker for whether an organism should be classified as a gram-positive. That criterion can no longer be relied upon because of emerging resistance among some species. Gram-negative bacteria, viruses, fungi, and parasites all have succeeded in developing resistance.