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The integration of biology, genomics, and health has opened the possibility of applying genomics technology to nutrition. In 2001, scientists associated with the Human Genome Project announced the successful mapping of the reference sequence of the human genome. Since then, a body of information has emerged. Genomics and related areas of research have contributed greatly to efforts to understand the cellular and molecular mechanisms underlying diet-disease relationships. Integration and application of genetic and genomics technology into nutrition research is, therefore, needed to develop nutrition research programs that are aimed at the prevention and control of chronic disease through genomics-based nutritional interventions. Of interest is the integration of relevant computational methods into nutritional genomics research; the enhancement of tools applicable to systems biology; and the effective dissemination of genomics-derived information to scientists, policy makers, and the interested public. To address these issues, a workshop was held on June 1 and 2, 2006. The workshop included presentations that were structured around three focus sessions: human genetic variation, epigenetics, and systems biology. A fourth session presented discussions on the implications of nutrigenomics for the future of nutrition science research. Numerous themes emerged from the workshop presentations. First, nutrigenomics is a complex field because it addresses issues related to multigenetic traits that can be modified by a number of nutritional and other environmental factors. Such complexity presents a challenge to the field; and the ensuing research opportunities will require cooperative work among scientific disciplines and across government, academic, and industrial centers, as well as adequate funding, to be realized. Additionally, the ability to stretch the limits of conventional research methodologies afforded by new genetic and genomic applications at the level of the individual opens the door to a wealth of potential benefits to areas such as disease prevention and wellness, bearing in mind the necessity of ethical safeguards. This potential, however, must be wisely exploited to avoid the pitfalls of overpromising research results and prematurely setting unrealistic expectations for beneficial outcomes. Finally, careful and rigorous research must be employed to optimize outcomes and assure acceptance by the scientific community. In summary, nutrition science is uniquely poised to serve as the crossroads for many disciplines and, using genomics tools, can bring this knowledge together to better understand and address diet-related chronic diseases and molecular responses to dietary factors.
On December 5, 2017, the National Academies of Sciences, Engineering, and Medicine hosted a public workshop titled Nutrigenomics and the Future of Nutrition in Washington, DC, to review current knowledge in the field of nutrigenomics as it relates to nutrition. Workshop participants explored the influence of genetic and epigenetic expression on nutritional status and the potential impact of personalized nutrition on health maintenance and chronic disease prevention. This publication summarizes the presentations and discussions from the workshop.
Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is the most comprehensive foundational text on the complex topics of nutrigenetics and nutrigenomics. Edited by three leaders in the field with contributions from the most well-cited researchers conducting groundbreaking research in the field, the book covers how the genetic makeup influences the response to foods and nutrients and how nutrients affect gene expression. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is broken into four parts providing a valuable overview of genetics, nutrigenetics, and nutrigenomics, and a conclusion that helps to translate research into practice. With an overview of the background, evidence, challenges, and opportunities in the field, readers will come away with a strong understanding of how this new science is the frontier of medical nutrition. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is a valuable reference for students and researchers studying nutrition, genetics, medicine, and related fields. - Uniquely foundational, comprehensive, and systematic approach with full evidence-based coverage of established and emerging topics in nutrigenetics and nutrigenomics - Includes a valuable guide to ethics for genetic testing for nutritional advice - Chapters include definitions, methods, summaries, figures, and tables to help students, researchers, and faculty grasp key concepts - Companion website includes slide decks, images, questions, and other teaching and learning aids designed to facilitate communication and comprehension of the content presented in the book
We live in a society where we are stressed emotionally, financially, physically and exposed to a range of toxins in our environment. Combining underlying genetic susceptibility with these factors provides all the ingredients for a perfect health storm. By understanding where our weak points are located, or where the accidents are on our particular highway of life, it is possible to bypass those detours, accidents and breakdowns and chart a better Roadmap to Health. This book defines those steps needed to begin your own personal journey to health and wellness.
Dr. Perricone’s FOREVER YOUNG makes an extraordinary promise: by following a program designed to decrease wrinkles and dramatically improve the appearance of the skin, the reader is also guaranteed more energy, less fat and an improved mood. The core of Dr. Perricone’s appeal is his scientific grounding and authority. In a field notorious for the triumph of style over substance, Dr. Perricone is at the cutting edge of new science which is scientifically proven to work. At the core of the new book is an exciting new science on skin: Nutrigenomics and gene expression. With his innovative vision, Dr. Perricone has applied the new science to ease wrinkles, make the skin supple, smooth and glowing. His prescriptive program will shave years off the reader's appearance and will give the reader more energy.
Nutrigenomics seeks to understand the variability of the individual's response to food and the underlying mechanisms whereby foods exert their health-promoting activities. With a deeper molecular understanding of nutrition, we may some day be able to design diets that truly maximize an individual's potential for health and wellness. Many Asian societies are currently experiencing a transition in diet-related morbidity and mortality. The identification and provision of an optimal diet relevant to all the people living in Asia is an extraordinary challenge as there exists a tremendous diversity in diet, dietary intake patterns, local culture, and nutritional needs. This volume explores the role of ethnic diversity, dietary patterns and genetic adaptation in determining individual nutrient requirements throughout the life-cycle. Conceptualized as an introductory publication providing a general overview as well as specific examples of the applications of concepts and methods, this publication will help scientists, medical, nutrition and other health professionals to learn more about the field of nutrigenomics.
While functional foods have become a reasonably well-established concept, personalized nutrition is still treated with skepticism by many. The recognition that people would have different nutrient requirements, or perceive foods in different ways, raises several concerns-some real, some not so real. Nutrigenomics and Nutrigenetics in Functional Foo
This volume of Progress in Molecular Biology and Translational Science covers the recent advances in the expanding fields of nutrigenetics and nutrigenomics. Forty authors from eight countries have contributed to the publication, representing the most cutting-edge research available. - Contributions from leading authorities - Informs and updates on all the latest developments in the field
For the first time, international scientists describe the advances in genetics and nutrition by combining methods of molecular biology with those of functional genetics, also known as systems biology. This book provides the latest data on genetic variation and dietary response, nutrients and gene expression, and the contribution molecular biology has given to systems biology. It also includes a comprehensive critique of genetic association studies in defining the risk of chronic diseases and concludes that molecular diagnostic tests will eventually affect every area of health care from individual risk prediction, early diagnosis of disease, and determination of optimal treatment regimens, to monitoring treatment effectiveness. The appendix contains an extensive glossary of the newly emerging terminology, as well as recommendations for genetic screening. This publication is an essential tool for the future work of all physicians, nutritionists, dietitians, geneticists, physiologists, molecular biologists, anthropologists, food technologists, policy makers, ethicists and educators.
**Selected for Doody's Core Titles® 2024 in Dental Hygiene & Auxiliaries** Learn how to apply nutritional principles to promote optimal patient care! The Dental Hygienist's Guide to Nutritional Care, 5th Edition explains how teaching proper nutrition can improve your clients' oral and systemic health. Case studies and clear, full-color photos and illustrations provide a basis for assessing, diagnosing, planning, implementing, and evaluating the care of patients. In addition, a solid foundation in nutrition prepares you for the subject's increased emphasis on the NBDHE examination. Written by an interdisciplinary author team with expertise in nutrition and dental hygiene, this book was the first nutritional guide designed specifically for dental hygienists! - UNIQUE! Biochemistry chapter covers the essential concepts tested on the National Board Dental Hygiene Examination (NBDHE). - UNIQUE! Coverage of vitamins and minerals is based on the oral effects of micronutrients. - Clinically relevant applications to dental hygiene include a focus on patient education and dental hygiene considerations in each chapter. - Case studies and Health Applications demonstrate how nutrition concepts can be applied to specific patient situations. - Learning features include pretests and key terms highlighted in each chapter, with definitions in the glossary. - Practice quizzes online allow you to test your comprehension, and include feedback and remediation for incorrect answers. - NEW! Updated content addresses interdisciplinary practice and the FDA's Food Safety Modernization Act, with expanded coverage of older adults, vitamin D, and nutrigenomics. - NEW! Coverage of the latest federal nutrition standards includes the Dietary Guidelines for Americans, the Nutrition Facts label, and more. - NEW! UPDATED full-color illustrations include additional clinical photos as well as food-source photos in the micronutrient chapters.