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This book presents a road map for applying the stages in conceptualization, evaluation, and testing of biomedical devices in a systematic order of approach, leading to solutions for medical problems within a well-deserved safety limit. The issues discussed will pave the way for understanding the preliminary concepts used in modern biomedical device engineering, which include medical imaging, computational fluid dynamics, finite element analysis, particle image velocimetry, and rapid prototyping. This book would undoubtedly be of use to biomedical engineers, medical doctors, radiologists, and any other professionals related to the research and development of devices for health care.
This book explores computational fluid dynamics in the context of the human nose, allowing readers to gain a better understanding of its anatomy and physiology and integrates recent advances in clinical rhinology, otolaryngology and respiratory physiology research. It focuses on advanced research topics, such as virtual surgery, AI-assisted clinical applications and therapy, as well as the latest computational modeling techniques, controversies, challenges and future directions in simulation using CFD software. Presenting perspectives and insights from computational experts and clinical specialists (ENT) combined with technical details of the computational modeling techniques from engineers, this unique reference book will give direction to and inspire future research in this emerging field.
The continuous growth of knowledege makes it very difficult for scientists to retrieve comprehensive and accurate data on viruses. The desired information is often dispersed in a variety of books, journals and online resources. This encyclopedia presents the latest facts about all known viruses in a standardized form created by hundreds of the world's leading virologists. Virus taxonomy represents the basic framework that allows an understanding of the complex evolutionary process that continuously takes place among viruses and their hosts. Each of the 300 taxonomically ordered chapters includes detailed information on individual genus members, historical events, the hosts they can affect (animal, man or plant), virion morphology, genome properties, replication strategy, properties of individual transcripts and proteins, sequence accession numbers, biological properties, diseases, recombinant vector constructs, vaccine strains, key references, as well as a high-resolution particle image and a drawing of the genome organization. Its high content of easily accessible detailed information makes this Encyclopedia an indispensable tool for both researchers and lecturers. The new edition includes the recent discoveries made in this field as well as new viruses which have been discovered.
This volume presents the proceedings of the CLAIB 2016, held in Bucaramanga, Santander, Colombia, 26, 27 & 28 October 2016. The proceedings, presented by the Regional Council of Biomedical Engineering for Latin America (CORAL), offer research findings, experiences and activities between institutions and universities to develop Bioengineering, Biomedical Engineering and related sciences. The conferences of the American Congress of Biomedical Engineering are sponsored by the International Federation for Medical and Biological Engineering (IFMBE), Society for Engineering in Biology and Medicine (EMBS) and the Pan American Health Organization (PAHO), among other organizations and international agencies to bring together scientists, academics and biomedical engineers in Latin America and other continents in an environment conducive to exchange and professional growth.
This book is designed to provide all the information required for a sound understanding of diseases of the nose and paranasal sinuses and the surgical techniques used in their management. After an opening section on basic science, clinical and radiological assessment is explained and individual chapters focus on conditions ranging from infectious diseases, allergic rhinitis, and nasal polyposis to trauma, malignancies, and skin diseases. A wide variety of surgical techniques are then described with the aid of high-quality illustrations, covering nasal airway procedures and surgical approaches to the paranasal sinuses, including diverse endoscopic and image-guided procedures, nasal reconstruction, and endonasal and external rhinoplasty. The book is a collaborative project between the new generation of Turkish specialists and well-known experts from across the world. It will be of value for ENT doctors in all countries, as well as for students and trainees and those working in ENT-related fields such as maxillo-facial surgery, pediatrics, allergology, neurology, infectious diseases, and neurosurgery.
Diseases of the Sinuses: A Comprehensive Textbook of Diagnosis and Treatment, 2nd Edition, offers the definitive source of information about the basic science of the sinuses and the clinical approach to sinusitis. Since the widely praised publication of the first edition, understanding of sinus disease has changed dramatically, mainly as a result of recent developments and new discoveries in the field of immunology. This updated and expanded edition is divided into sections addressing, separately, the pathogenesis, clinical presentation, medical and surgical management of acute and chronic rhinosinusitis. Special entities such as autoimmune-related sinusitis, allergy and sinusitis, and aspirin-exacerbated respiratory disease are discussed in separate chapters. The role of immunodeficiency is also addressed. The management section has been fully updated to incorporate new medical modalities and surgical procedures. Developed by a distinguished group of international experts who share their expertise and insights from years of collective experience in treating sinus diseases, the book will appeal to anyone who has an interest in sinus disease, including both physicians and allied health professionals. Internists, pediatricians, allergists, otolaryngologists and infectious disease specialists will find the book to be an invaluable, comprehensive reference. Physician assistants and nurse practitioners who work with specialists who treat sinus disease will also benefit from the book.
The Multiphase Flow Handbook, Second Edition is a thoroughly updated and reorganized revision of the late Clayton Crowe’s work, and provides a detailed look at the basic concepts and the wide range of applications in this important area of thermal/fluids engineering. Revised by the new editors, Efstathios E. (Stathis) Michaelides and John D. Schwarzkopf, the new Second Edition begins with two chapters covering fundamental concepts and methods that pertain to all the types and applications of multiphase flow. The remaining chapters cover the applications and engineering systems that are relevant to all the types of multiphase flow and heat transfer. The twenty-one chapters and several sections of the book include the basic science as well as the contemporary engineering and technological applications of multiphase flow in a comprehensive way that is easy to follow and be understood. The editors created a common set of nomenclature that is used throughout the book, allowing readers to easily compare fundamental theory with currently developing concepts and applications. With contributed chapters from sixty-two leading experts around the world, the Multiphase Flow Handbook, Second Edition is an essential reference for all researchers, academics and engineers working with complex thermal and fluid systems.
The Multiphase Flow Handbook, Second Edition is a thoroughly updated and reorganized revision of the late Clayton Crowe’s work, and provides a detailed look at the basic concepts and the wide range of applications in this important area of thermal/fluids engineering. Revised by the new editors, Efstathios E. (Stathis) Michaelides and John D. Schwarzkopf, the new Second Edition begins with two chapters covering fundamental concepts and methods that pertain to all the types and applications of multiphase flow. The remaining chapters cover the applications and engineering systems that are relevant to all the types of multiphase flow and heat transfer. The twenty-one chapters and several sections of the book include the basic science as well as the contemporary engineering and technological applications of multiphase flow in a comprehensive way that is easy to follow and be understood. The editors created a common set of nomenclature that is used throughout the book, allowing readers to easily compare fundamental theory with currently developing concepts and applications. With contributed chapters from sixty-two leading experts around the world, the Multiphase Flow Handbook, Second Edition is an essential reference for all researchers, academics and engineers working with complex thermal and fluid systems.
Traditional research methodologies in the human respiratory system have always been challenging due to their invasive nature. Recent advances in medical imaging and computational fluid dynamics (CFD) have accelerated this research. This book compiles and details recent advances in the modelling of the respiratory system for researchers, engineers, scientists, and health practitioners. It breaks down the complexities of this field and provides both students and scientists with an introduction and starting point to the physiology of the respiratory system, fluid dynamics and advanced CFD modeling tools. In addition to a brief introduction to the physics of the respiratory system and an overview of computational methods, the book contains best-practice guidelines for establishing high-quality computational models and simulations. Inspiration for new simulations can be gained through innovative case studies as well as hands-on practice using pre-made computational code. Last but not least, students and researchers are presented the latest biomedical research activities, and the computational visualizations will enhance their understanding of physiological functions of the respiratory system.
The focus of this book is on subjects related to drug delivery to the lung. The text spans topics from aerosol deposition through pharmaceutical chemistry and formulation to the final clinical evaluation of pharmaceutical products. Utilizing a multi-disciplinary approach, the chapters consider toxicology from the point of view of drugs and pharmaceutical excipients used in aerosols.