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A comprehensive standard work and important resource for both students and professionals in research and industry who need detailed knowledge of the theory and applications. Many numerical examples and numerous illustrations visualize the theoretical issues, backed by many useful tables and charts, plus over 500 illustrations. The Handbook discusses the latest developments in vacuum measurement techniques and leak detection in vacuum systems, as well as the connection of vacuum systems to computerized control systems.
This book describes technical and practical aspects of pipeline damage. It summarizes the phenomena, mechanisms and management of pipeline corrosion in-service. The topics discussed include pipelines fracture mechanics, damage mechanisms and evolution, and pipeline integrity assessment. The concept of acceptable risk is also elucidated and the future application of new knowledge management tools is considered.
Based on the very successful German edition and a seminar held by the German Engineers` Association (VDI) on a regular basis for years now, this English edition has been thoroughly updated and revised to reflect the latest developments. It supplies in particular the special aspects of vacuum technology, applied vacuum pump types and vacuum engineering in the chemical, pharmaceutical and process industry application-segments. The text includes chapters dedicated to latest European regulations for operating in hazardous zones with vacuum systems, methods for process pressure control and regulation and leak detection. All of the authors work or did work at a selection of the most important German companies involved in vacuum technology, and their expertise is disseminated here for engineers working in vacuum technology, chemical process design, plant operation, and mechanical engineering.
Comprehensive guide to the basic principles and applications of non-destructive testing methods for aircraft system and components: airframe, propulsion, landing gear and more Provides detailed analysis of the advantages and disadvantages of major NDT methods Important for design, inspection, maintenance, repair, corrosion protection and safety This critical book is among the first to provide a detailed assessment of non-destructive testing methods for the many materials and thousands of parts in aircraft. It describes a wide variety of NDT techniques and explains their application in the evaluation and inspection of aerospace materials and components ranging from the entire airframe to systems and subsystems. At the same time the book offers guidance on the information derived from each NDT method and its relation to aircraft design, repair, maintenance and overall safety. The book covers basic principles, as well as practical details of instrumentation, procedures and operational results with a full discussion of each method's capabilities and limitations as these pertain to aircraft inspection and different types of materials, e.g., composites and metal alloys. Technologies covered include: optical and enhanced optical methods; liquid penetrant, replication and magnetic particle inspection; electromagnetic and eddy current approaches; acoustics and ultrasonic techniques; infrared thermal imaging; and radiographic methods. A final section is devoted to NDT reliability and ways the probability of detection can be measured to establish inspection intervals.
Combination products are therapeutic and diagnostic products that combine drugs, devices, and/or biological products. According to the US Food and Drug Administration (FDA), “a combination product is one composed of any combination of a drug and a device; a biological product and a device; a drug and a biological product; or a drug, device and a biological product.” Examples include prefilled syringes, pen injectors, autoinjectors, inhalers, transdermal delivery systems, drug-eluting stents, and kits containing drug administration devices co-packaged with drugs and/or biological products. This handbook provides the most up-to-date information on the development of combination products, from the technology involved to successful delivery to market. The authors present important and up-to-the-minute pre- and post-market reviews of international combination product regulations, guidance, considerations, and best practices. This handbook: Brings clarity of understanding for global combination products guidance and regulations Reviews the current state-of-the-art considerations and best practices spanning the combination product lifecycle, pre-market through post-market Reviews medical product classification and assignment issues faced by global regulatory authorities and industry The editor is a recognized international Combination Products and Medical Device expert with over 35 years of industry experience and has an outstanding team of contributors. Endorsed by AAMI – Association for the Advancement of Medical Instrumentation.
This updated Second Edition covers current state-of-the-art technology and instrumentation The Second Edition of this well-respected publication provides updated coverage of basic nondestructive testing (NDT) principles for currently recognized NDT methods. The book provides information to help students and NDT personnel qualify for Levels I, II, and III certification in the NDT methods of their choice. It is organized in accordance with the American Society for Nondestructive Testing (ASNT) Recommended Practice No. SNT-TC-1A (2001 Edition). Following the author's logical organization and clear presentation, readers learn both the basic principles and applications for the latest techniques as they apply to a wide range of disciplines that employ NDT, including space shuttle engineering, digital technology, and process control systems. All chapters have been updated and expanded to reflect the development of more advanced NDT instruments and systems with improved monitors, sensors, and software analysis for instant viewing and real-time imaging. Keeping pace with the latest developments and innovations in the field, five new chapters have been added: * Vibration Analysis * Laser Testing Methods * Thermal/Infrared Testing * Holography and Shearography * Overview of Recommended Practice No. SNT-TC-1A, 2001 Each chapter covers recommended practice topics such as basic principles or theory of operation, method advantages and disadvantages, instrument description and use, brief operating and calibrating procedures, and typical examples of flaw detection and interpretation, where applicable.