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This book collects several contributions, written both by statisticians and medical doctors, which focus on the identification of new diagnostic, therapeutic and organizational strategies in order to improve the occurrence of clinical outcomes for Acute Coronary Syndromes (ACS) patients. The work is structured in two different parts: the first one is focused on cooperative project mainly on statistical analysis of large clinical and administrative databases; the second one faces the development of innovative diagnostic techniques, with specific reference to genetic and proteomic, and the evolution of new imaging techniques for the early identification of patients at major risk of thrombotic, arrhythmic complications and at risk of poor revascularization.
The first Bayesian Young Statisticians Meeting, BAYSM 2013, has provided a unique opportunity for young researchers, M.S. students, Ph.D. students, and post-docs dealing with Bayesian statistics to connect with the Bayesian community at large, exchange ideas, and network with scholars working in their field. The Workshop, which took place June 5th and 6th 2013 at CNR-IMATI, Milan, has promoted further research in all the fields where Bayesian statistics may be employed under the guidance of renowned plenary lecturers and senior discussants. A selection of the contributions to the meeting and the summary of one of the plenary lectures compose this volume.
This volume includes contributions selected after a double blind review process and presented as a preliminary version at the 45th Meeting of the Italian Statistical Society. The papers provide significant and innovative original contributions and cover a broad range of topics including: statistical theory; methods for time series and spatial data; statistical modeling and data analysis; survey methodology and official statistics; analysis of social, demographic and health data; and economic statistics and econometrics.
Getting the right diagnosis is a key aspect of health care - it provides an explanation of a patient's health problem and informs subsequent health care decisions. The diagnostic process is a complex, collaborative activity that involves clinical reasoning and information gathering to determine a patient's health problem. According to Improving Diagnosis in Health Care, diagnostic errors-inaccurate or delayed diagnoses-persist throughout all settings of care and continue to harm an unacceptable number of patients. It is likely that most people will experience at least one diagnostic error in their lifetime, sometimes with devastating consequences. Diagnostic errors may cause harm to patients by preventing or delaying appropriate treatment, providing unnecessary or harmful treatment, or resulting in psychological or financial repercussions. The committee concluded that improving the diagnostic process is not only possible, but also represents a moral, professional, and public health imperative. Improving Diagnosis in Health Care, a continuation of the landmark Institute of Medicine reports To Err Is Human (2000) and Crossing the Quality Chasm (2001), finds that diagnosis-and, in particular, the occurrence of diagnostic errorsâ€"has been largely unappreciated in efforts to improve the quality and safety of health care. Without a dedicated focus on improving diagnosis, diagnostic errors will likely worsen as the delivery of health care and the diagnostic process continue to increase in complexity. Just as the diagnostic process is a collaborative activity, improving diagnosis will require collaboration and a widespread commitment to change among health care professionals, health care organizations, patients and their families, researchers, and policy makers. The recommendations of Improving Diagnosis in Health Care contribute to the growing momentum for change in this crucial area of health care quality and safety.
Acute Coronary Syndromes—a Companion to Braunwald’s Heart Disease—covers the state-of-the-art scientific and clinical information you need to rapidly evaluate and manage acute coronary syndromes. Dr. Pierre Theroux and his team of expert contributors present advances in diagnostic and imaging techniques such as biomarkers, nuclear cardiology, echocardiography, and multislice CT; secondary prevention; and new antiplatelet, anti-ischemic, and gene therapies. Tap into the most definitive knowledge available from one of the leading experts in the field and a stellar cast of contributors. Understand the special considerations for the care of acute coronary syndromes in the emergency department and the coronary care unit. Effectively handle the treatment of special populations and chronic patients thanks to coverage of these challenges See techniques and procedures in greater detail and clarity through the all-new full-color design. Approach treatment with a global perspective from the new section on Population-Based Perspective that discusses the INTERHEART study, insights from the REACH registry, lessons learned from European registries, and ACS in North America. Gain a comprehensive understanding of ACS through coverage of pathophysiology, molecular mechanisms, the role of the immune system, and brand-new chapters on cell necrosis and cell regeneration and pharmacogenetics in the section on Disease-Based Perspectives. Integrate the latest testing and treatment techniques into your practice thanks to new chapters on biomarkers in acute ischemic heart disease; the role of noninvasive testing in prognostic risk stratification; the culprit lesions and patient at risk; non-responsiveness to antiplatelet therapy; bleeding in the acute coronary syndromes; and the refractory patient.
Manage cardiovascular problems more effectively with the most comprehensive resource available! A trusted companion to Braunwald's Heart Disease, Cardiovascular Therapeutics, 4th Edition addresses pharmacological, interventional, and surgical management approaches for each type of cardiovascular disease. This practical and clinically focused cardiology reference offers a balanced, complete approach to all of the usual and unusual areas of cardiovascular disease and specific therapies in one concise volume, equipping you to make the best choices for every patient. Understand current approaches to treating and managing cardiovascular patients for long-term health, for complex problems, and for unusual cardiac events. Benefit from the substantial experience of Elliott M. Antman, MD, Marc S. Sabatine, MD, and a host of other respected authorities, who provide practical, evidence-based rationales for all of today's clinical therapies. Expand your knowledge beyond pharmacologic interventions with complete coverage of the most effective interventional and device therapies being used today. Easily reference Braunwald's Heart Disease, 9th Edition for further information on topics of interest. Make the best use of the latest genetic and molecular therapies as well as advanced therapies for heart failure. Cut right to the answers you need with an enhanced focus on clinically relevant information and a decreased emphasis on pathophysiology. Stay current with ACC/AHA/ESC guidelines and the best ways to implement them in clinical practice. Get an enhanced visual perspective with an all-new, full-color design throughout. Access the complete contents online and download images at www.expertconsult.com.
Are you a member of ACCA? Go to the ACCA website to find out about special offers on The ESC Textbook of Intensive and Acute Cardiovascular Care and to buy your copy today. The ESC Textbook of Intensive and Acute Cardiovascular Care is the official textbook of the Acute Cardiovascular Care Association (ACCA) of the ESC. This new updated edition continues to comprehensively approach all the different issues relating to intensive and acute cardiovascular care. The textbook is addressed to all those involved in intensive and acute cardiac care, from cardiologists to emergency physicians and healthcare professionals. The chapters cover the various acute cardiovascular diseases that need high quality intensive treatment, but also organisational issues, cooperation among professionals, and interaction with other specialities in medicine. The largest section of the textbook is devoted to non-cardiac disease which could acutely involve the cardiovascular system. Other noteworthy chapters are on ethical issues - which are so important in acute cardiac care, such as patient safety, donor organ management and palliative care. A unique characteristic of the textbook is the presence of a whole section devoted to biomarkers, which underline the growing importance of laboratory medicine in the field of intensive and acute cardiac care. A particular asset of the textbook is the digital version available on Oxford Medicine Online, which has additional online features including an extra chapter on lung ultrasound and many more images and videos, as well as a full list of references from all chapters. The online version is updated by the same authors on a yearly basis and is available with the print version and separately on a subscription basis, allowing easy access to content in digital and mobile optimised format. The textbook aligns directly with the core training curriculum for ACCA. This print edition of The ESC Textbook of Intensive and Acute Cardiovascular Care comes with access to the online version on Oxford Medicine Online, for as long as the edition is published by Oxford University Press. By activating your unique access code, you can read and annotate the full text online, follow links from the references to primary research materials, and view, enlarge and download all the figures and tables.
The management of non-ST segment elevation acute coronary syndromes(NSTE-ACS) has rapidly evolved over the last few years and manyguidelines have been provided and already updated. This book isbased on the latest ESC Guidelines and reports the currentknowledge in NSTE-ACS, together with the most recent therapeuticoptions and the different strategies that can be applied accordingto the clinical status of patients. International experts address the different aspects of NSTE-ACSand bring useful information to clinicians, interventionalists andsurgeons involved in the difficult management of thesepatients. The ESC Education Series This book is part of the ESC Education Series. The series isdesigned to provide medical professionals with the latestinformation about the understanding, diagnosis and management ofcardiovascular diseases. Where available, managementrecommendations are based on the established European Guidelines,which encompass the best techniques to use with each cardiacdisease. Throughout the series, the leading international opinionleaders have been chosen to edit and contribute to the books. Theinformation is presented in a succinct and accessible format with aclinical focus.
The pace of therapeutic advances in the treatment of cardiovascular diseases is rapid, and new clinically-relevant information appears with such frequency that it can be extremely challenging for clinicians to keep up. Still, knowledge and interpretation of major clinical trials is crucial for the range of clinicians who manage cardiovascular patients, especially since important trial evidence often needs to be implemented soon after it is published. Confidently apply gold standard treatment for 10 of the most critical areas of cardiology Written by an international team of experts, Cardiovascular Clinical Trials: Putting the Evidence into Practice: Provides a succinct overview of recent major clinical trials - the gold standard for all medical treatment - across all the major cardiovascular subspecialties, to ensure you’re up-to-date on the most critical findings Guides cardiology trainees and clinicians on how cardiovascular clinical trials are designed and conducted, including statistical methodology, so you can conduct and/or appraise future trials yourself Addresses methodology as well as clinical effectiveness Offers evidence-based assessments on the most effective treatments and authoritative clinical information on management of the conditions so you can confidently apply what you learn Physicians, surgeons, specialist nurses – any clinician seeking an accessible resource for designing and conducting cardiovascular trials and then translating their results into practice will appreciate this book’s clear guidance and succinct and practical approach.