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First multi-year cumulation covers six years: 1965-70.
Includes entries for maps and atlases.
Frank Schmitt has for two thirds of a century been searching for -- and in many cases finding -- explanations of major biomedical importance. His is a very human story -- of a youth in high school doing experiments in a make-shift chemical laboratory in the attic of the family home; of a young university student who organized a students' science society and whose undergraduate research on cell structure was published in major professional journals; of a medical school student who wrote a thesis that attracted the attention of cardiologists for many years; of a devoted husband who, with his young wife, spent two postdoctoral years in Berkeley, London and Berlin and later made two trips around the world with her as he set up a worldwide network of neuroscientists. As a young scientist at Washington University, Schmitt investigated polarization optical and x-ray diffraction methods to discover the molecular structure of living tissues -- this, long before molecular biology was established as a scientific discipline. Schmitt was called to head biology at MIT in 1941. There he added electron microscopy to his ultrastructural repertoire and used much of it in wartime research. As an Institute Professor (MIT's highest rank), he became a leader in the founding and characterization of the fields of biophysic and neuroscience. Schmitt was also deeply committed to music, along with his wife, and had an interest in theology. Photos.
It has been recognized for more than a thousand years that the function of the brain, like the function of the other organs of the body, is determined by its physical, chemical, and biological properties. Evidence that even its highest functions could be explained by these properties was gathered only in recent years, however; these findings, which clearly have to be confirmed by a great deal of further experimental evidence, indicate that most, if not all, of the functions of the brain are based on its bio chemical and biophysical mechanisms. This at first hearing may sound rather simple, but the ability to understand learning, emotion, perhaps even creativity, on biological terms may well be the most important scientific discovery of all time. Few pieces of knowledge can influence our future health and well-being to the degree that understanding of mental mechanisms will. It has been clearly shown in many ways in the previous volumes of this Handbook that from the biochemical or neurochemical point of view the brain is one of the most active organs. The brain seems stable and in some respects permanent; this is evidence not of inactivity but of carefully controlled homeostasis, of dynamic rather than static equilibrium, with most components undergoing metabolic alterations.