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This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.
This book is an up-to-date, comprehensive review of the neuropsychiatry of multiple sclerosis and related diseases, by active authorities in the field, with an emphasis on diagnosis and management. Critical appraisal of the methodological aspects and limitations of the current research on the neuropsychiatry of demyelinating diseases is included, and unanswered questions are highlighted. Pharmacological aspects of management are discussed. Neuropsychiatric Symptoms of Inflammatory Demyelinating Diseases is aimed at neurologists, multiple sclerosis specialists and psychiatrists, and will also be of interest to intensive care doctors, psychologists ad neuropsychologists, research and specialist nurses, clinical researchers and methodologists.
This collection of pediatric clinical cases focus on multiple sclerosis, neuromyelitis optica, acute disseminated encephalomyelitis and mimics. Dedicated sections on diseases affecting the brain, brainstem, spinal cord and the optic nerve feature chapters that include the diagnostic work up, therapeutic management and case outcome. Typical and atypical presentations of various pediatric demyelinating diseases also emphasize therapy response and those that breakthrough on treatment. Filling a critical gap in the literature on inflammatory disorders of the central nervous system, all those that treat patients with these rare and challenging disorders will find this book extremely helpful for their daily clinical practice.
This thoroughly updated edition covers all clinical aspects of neuroinflammation. The latest developments in pathogenesis and advances in treatment are provided, along with an understanding of the immune system's role and interactions between the activated immune cells, cerebral endothelial cells, and other main components of the immune cascade. Cutting-edge and authoritative, this volume offers practitioners a valuable resource for research and clinical practice.
This book provides cutting-edge information on the epidemiology, etiopathogenesis, clinical manifestations, diagnostic procedures and treatment approaches for the main white matter (WM) disorders of the central nervous system (CNS). WM lesions are associated with many neurological conditions, and with aging. The diagnostic work-up of neurological diseases characterized by the presence of these lesions has changed dramatically over the past few years. This is mainly due on the one hand to the discovery of specific pathogenetic factors in some of these conditions, and on the order to the optimized use of diagnostic tools. All of this has resulted in new diagnostic algorithms, and in the identification of new neurological conditions. The book offers neurologists essential guidance in the diagnosis and treatment of the most frequent WM conditions, promoting their correct and cost-saving diagnosis and management. By integrating neurological, laboratory and imaging concepts with the demands of accurate diagnosis, this reference guide provides a state-of-the-art overview of the current state of knowledge on these conditions, as well as practical guidelines for their diagnosis and treatment.
This book is an up-to-date, comprehensive review of the neuropsychiatry of different types of cognitive impairment by active authorities in the field. There is an emphasis on diagnostic and management issues. Cognitive impairment both with and without criteria for dementia is covered. A critical appraisal of the methodological aspects and limitations of the current research on the neuropsychiatry of cognitive impairment and dementia is included. Unanswered questions and controversies are addressed. Non-pharmacological and pharmacological aspects of management are discussed, to provide robust information on drug dosages, side effects and interaction, in order to enable the reader to manage these patients more safely. Illustrative cases provide real life scenarios that are clinically relevant and engaging to read. Neuropsychiatric Symptoms of Cognitive Impairment and Dementia is aimed at neurologists, psychiatrists, gerontologists, and general physicians. It will also be of interest to intensive care doctors, psychologists and neuropsychologists, research and specialist nurses, clinical researchers and methodologists.
Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.
This is an up-to-date, comprehensive review of the neuropsychiatry of patients with movement disorders, i.e. Parkinson’s disease, Huntington’s disease, dystonia and others, by active authorities in the field, with an emphasis on diagnostic and management issues. This book includes critical appraisal of the methodological aspects and limitations of the current research on the neuropsychiatry of movement disorders and on unanswered questions/controversies. Symptomatology and pharmacological aspects of management are discussed, to provide robust information on drug dosages, side effects and interaction, in order to enable the reader to manage these patients more safely. Illustrative cases provide real life scenarios that are clinically relevant and engaging to read. Neuropsychiatric Symptoms of Movement Disorders is aimed at neurologists, movement disorder specialists and psychiatrists and will also be of interest to intensive care doctors, psychologists and neuropsychologists, research and specialist nurses, clinical researchers and methodologists.
Presenting the novel concept of white matter dementia, this unique book offers hope for a better understanding and treatment of dementia.