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This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.
The book provides chapters on sex hormones and their modulation in neurodegenerative processes and pathologies, from basic molecular mechanisms, physiology, gender differences, to neuroprotection and clinical aspects for potential novel pharmacotherapy approaches. The book contains 14 chapters written by authors from various biomedical professions, from basic researchers in biology and physiology to medicine and veterinary medicine, pharmacologists, psychiatrist, etc. Chapters sum up the past and current knowledge on sex hormones, representing original new insights into their role in brain functioning, mental disorders and neurodegenerative diseases. The book is written for a broad range of audience, from biomedical students to highly profiled medical specialists and biomedical researchers, helping them to expand their knowledge on sex hormones in neurodegenerative processes and opening new questions for further investigation.
A concise and innovative account of clinical neuroendocrine disorders and the key principles underlying their diagnosis and management.
'Equine Exercise Physiology' provides up-to-date coverage of the basic sciences required for an understanding of the physiology of the equine athlete.
This volume represents an up-to-date overview on pre-Menopause and Menopause, with their respective clinical implications and therapies. The aim is to clarify possible doubts and clinical approaches to this particular period in a woman’s life and how to face it, both offering solutions to actual problems and focusing on the potential impact of preventive medicine in improving women’s health and quality of life. The volume is published within the International Society of Gynecological Endocrinology (ISGE) Series, and is based on the 2017 International School of Gynecological and Reproductive Endocrinology Winter Course. This book, covering a very wide range of topics with particular focus on fertility in pre- and peri-menopausal women, climacteric and menopausal symptoms, impact of PCOS on post-menopausal health, breast disease, surgical treatments and therapies, will be an invaluable tool for gynecologists, endocrinologists, and experts in women’s health.
The subject of this book is neuroendocrinology, that branch of biological science devoted to the interactions between the two major integrative organ systems of animals-the endocrine and nervous systems. Although this science today reflects a fusion of endocrinology and neurobiology, this synthetic ap proach is relatively recent. At the beginning of the 20th century, when the British physiologists, Bayliss and Starling, first proposed endocrinology to be an independent field of inquiry, they went to great lengths to establish the autonomy of chemical secretions in general and their independence from nervous control in particular (Bayliss, W. M. , and Starling, E. H. , 1902, The mechanism of pancreatic secretion,]. Physiol. 28:325). They argued with Pav lov, who said that there was a strong influence of the nervous system on the gastrointestinal phenomena the endocrinologists were studying. For several decades, the English physiologists prevailed, at least in the West; and Pavlov's critique was not taken to heart by the practitioners of the newly emerging discipline of endocrinology. Through the work of Harris, the Scharrers, Sawyer, Everett, and others, there has been something of a scientific detente in the latter half of this century; the hybrid field of neuroendocrinology is now regarded as one of the corner stones of modern neural science and is of fundamental importance in basic and clinical endocrinology.
With contributions by numerous experts
An Independent Publisher Book Awards Gold Medal Winner A Progressive Book of the Year A TechCrunch Favorite Read of the Year “Deeply researched and thoughtful.” —Nature “An extended exercise in myth busting.” —Outside “A critique of both popular and scientific understandings of the hormone, and how they have been used to explain, or even defend, inequalities of power.” —The Observer Testosterone is a familiar villain, a ready culprit for everything from stock market crashes to the overrepresentation of men in prisons. But your testosterone level doesn’t actually predict your appetite for risk, sex drive, or athletic prowess. It isn’t the biological essence of manliness—in fact, it isn’t even a male sex hormone. So what is it, and how did we come to endow it with such superhuman powers? T’s story begins when scientists first went looking for the chemical essence of masculinity. Over time, it provided a handy rationale for countless behaviors—from the boorish to the enviable. Testosterone focuses on what T does in six domains: reproduction, aggression, risk-taking, power, sports, and parenting, addressing heated debates like whether high-testosterone athletes have a natural advantage as well as disagreements over what it means to be a man or woman. “This subtle, important book forces rethinking not just about one particular hormone but about the way the scientific process is embedded in social context.” —Robert M. Sapolsky, author of Behave “A beautifully written and important book. The authors present strong and persuasive arguments that demythologize and defetishize T as a molecule containing quasi-magical properties, or as exclusively related to masculinity and males.” —Los Angeles Review of Books “Provides fruitful ground for understanding what it means to be human, not as isolated physical bodies but as dynamic social beings.” —Science
Sexual compatibility between male and female partners is in dispensable to normal and successful fertilization in mammals. Thus, the genes from males and females whose sexual behavior is characterized by awkwardness, ineptness, and miscues are elimi nated from the gene pool of the species. In human societies, this compatibility is not always evident; and the behavior that precedes and accompanies copulation and fertilization is exceed ingly complex and affected by many variables. As in most other species of animals, the entire repertoire of reproductive behavior of man is not well understood by man. When viewed, discussed, or reported, the topic is too often and most unfortunately regarded as an amalgam of emotion, mysticism, and biology. In the past, such emotion-charged approaches to the biologi cal fact of reproduction did much to obfuscate the subject; and as a result, much of the array of hormonal, neural, psychological, and social variables that control and insure the successful repro duction of the human species remains even now in Victorian ignor ance. But with the recent rash of books and scientific treatises on the subject, some progress has been made in elucidating human reproduction and associated sexual behavior. However, so entrench ed are some of our social taboos that the danger still lurks of equating social acceptance of the words with an understandin- all too lacking--of the process to which they refer.