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Neurocysticercosis is the most common parasitic disease of the nervous system worldwide. This is a comprehensive, single-source review of the history, epidemiology, biological and parasitological features of the disease, as well as its immunological, clinical, diagnostic and therapeutic aspects.
Expanded and revised, this unique book provides concise descriptions of the many causes of epilepsy, for use in clinical practice.
Cysticercosis, an infection caused by the cystic larvae of the pork tapeworm Taenia solium, is one of the most frequent parasitic infections of the human nervous system (neurocysticercosis). It is endemic in most of Latin America, the sub-Saharan Africa, and vast parts of Asia, including the Indian subcontinent. It has also been increasingly diagnosed in developed countries because of migration of people from endemic zones and exposure in travelers. The life cycle involves the development of the adult tapeworm in the human small intestine (after ingesting infected pork with cysts) and larval infection in pig tissues (after ingesting human stools containing the eggs of the tapeworm). Humans get infected by the fecal-oral route, most often from a direct contact with an asymptomatic Taenia carrier. Most common clinical presentations are seizures (particularly late-onset seizures), chronic headaches, and intracranial hypertension. However, cysticerci can locate anywhere in the human nervous system, thus potentially causing almost any neurological syndrome and making clinical diagnosis a difficult task. Neuroimaging is the main diagnostic tool, and specific serology confirms the diagnosis and helps to define the diagnosis when images are unclear. Factors such as location (extraparenchymal versus intraparenchymal), number, size and evolutive stage of the parasites determine the clinical manifestations, therapeutic approach, and prognosis. Management includes symptomatic drugs (analgesics, antiepileptic drugs, anti-inflammatory agents) and in many cases cysticidal drugs, either albendazole or praziquantel. In recent years, efforts have focused on transmission control and potential elimination in endemic regions.
Solitary Cysticercus Granuloma Is One Of The Most Common Parasitic Diseases Of The Brain. This Monograph Is The Outcome Of Research Undertaken At Cmc, Vellore. It Also Takes Into Account Recent Work In Other Parts Of The World. The Contributors Include Neurologists, Neurosurgeons, Neurochemists And Neuropathologists.
Taenia solium cysticercosis is a parasitic disease caused by the dissemination of the larval form of the pork tapeworm and affects an estimated 50 million people worldwide. It is endemic in several developing countries, including many in Central and South America, Africa and South Asia. Through increased immigration and international travel, it is also of emerging significance in developed countries such as the USA.This book, written by international leading experts in the field, covers the basic science and clinical aspects of Taenia solium, its pathology, investigational aspects of neurocysticercosis, and therapy and prevention
​Neurocysticercosis (neural infection by larvae of Taenia solium) occurs when humans become intermediate hosts of the tapeworm Taenia solium after ingesting its eggs. The disease is now the most common helminthic infection of the nervous system in humans, and its prevalence has risen significantly even in countries where it was formerly considered exotic. The introduction of modern neuroimaging and serologic techniques has improved the diagnosis of neurocysticercosis; furthermore, the development of potent cysticidal drugs has changed the prognosis of most affected patients. Nevertheless, much remains to be learned about this parasitic disease. This book provides a comprehensive and up-to-date review of the various aspects of cysticercosis of the nervous system that will be of interest to all who are involved in the care of patients with this disease. Epidemiology, neuropathology, immunopathogenesis, clinical manifestations, diagnosis, and management are all thoroughly discussed based on current evidence and practice.
Focusing solely on uveitis care, this quick reference guide will provide a compiled and easy to navigate differential diagnosis – making an often daunting task for clinicians easier, quicker, and more accurate by using a concise outline format to list the most critical aspects of a disease entity. Uveitis: A Quick Guide to Essential Diagnosis opens with a Diagnosis Flowchart, so that the reader can select the most probable diagnoses based on patient’s history and exam. From there the reader can then quickly turn to the corresponding chapter to learn about the most critical aspects of the disease entity: epidemiology, characteristic exam and imaging findings, prognostic factors, and treatment options. This book is written for ophthalmic care providers including general ophthalmologists, subspecialists, fellows, residents and optometrists and features research and contributions from institutions that are global leaders in uveitis care.
This book provides updated information to scientists and clinicians on taeniosis/cysticercosis, a parasitic infection caused by eating undercooked beef or pork that is a serious health and veterinary problem in many developing countries. It discusses incidence, risk factors, diagnosis, immunology, symptoms, rare manifestations, and advances in treatment including vaccination and novel drug therapies.
This book includes selected peer-reviewed chapters which cover novel aspects of cysticercosis and neurocysticercosis written by well known international researchers, representing the most relevant Working Group for Cysticercosis of Mexico, Peru, Ecuador, most of the Eastern and Southern Africa countries and Europe plus other contributions from Canada and United States of America. Unfortunately, our colleagues from Asia could not participate in this project for several reasons but we hereby acknowledge their contribution to the scientific level reached by the international scientific community. Apart from the classic issue that cannot be missing in any book about cysticercosis/ neurocysticercosis, we introduced a new hypotheses and novel aspects on historical background, clinical descriptions, investigations, and treatment modalities related to this zoonotic parasitic disease as a leading cause of epilepsy in developing countries. We are looking forward with confidence and pride in the vital role that this book will play for a new vision and mission.