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In the last decade, bioimaging and therapy based on near-infrared (NIR) nanomaterials have played an important role in biotechnology due to their intrinsic advantages when compared with the traditional imaging probe and medicine. NIR nanomaterials allow deeper penetration depth, low detection threshold concentration and better targeted performance. This book systematically summarises the recent progress in the fabrication and application of NIR nanomaterials for biomedical imaging and therapy, and discusses the advantages, challenges and opportunities available. Near-infrared Nanomaterials contains achapter highlighting the outlook of these materials, detailing novel ideas for the further application of NIR nanomaterials in bioimaging and medicine. Written by leading experts working in the field, this title will have broad appeal to those working in chemistry, materials science, nanotechnology, biology, bioengineering, biomedical science and biophysics.
The exploration of photothermal nanomaterials with high light-to-heat conversion efficiency has paved the way for practical applications, including in cancer therapy, environmental remediation, catalysis, imaging and biomedicine. Covering the photothermal effect of different categories of light-absorbing nanomaterials, and focusing on metallic nanomaterials, 2D materials, semiconductors, carbon-based nanomaterials, polymeric nanomaterials and their composites, chapters in this book provide a systematic summary of recent advances in the fabrication and application of photothermal nanomaterials, discussing advantages, challenges and potential opportunities. This text will be a valuable resource for scientists working on photothermal nanomaterials, as well as those interested in the applications across chemistry, biomedicine, nanotechnology and materials science.
In the last decade, bioimaging and therapy based on near-infrared (NIR) nanomaterials have played an important role in biotechnology due to their intrinsic advantages when compared with the traditional imaging probe and medicine. NIR nanomaterials allow deeper penetration depth, low detection threshold concentration and better targeted performance. This book systematically summarises the recent progress in the fabrication and application of NIR nanomaterials for biomedical imaging and therapy, and discusses the advantages, challenges and opportunities available. Near-infrared Nanomaterials contains a chapter highlighting the outlook of these materials, detailing novel ideas for the further application of NIR nanomaterials in bioimaging and medicine. Written by leading experts working in the field, this title will have broad appeal to those working in chemistry, materials science, nanotechnology, biology and bioengineering, biomedical science and biophysics.
​This book analyzes and evaluates the growing field of light-emitting nanoprobes as contrast agents for in vivo imaging and sensing. It is a comprehensive resource that critically analyzes the state of the art in an interdisciplinary manner, with a special focus on the shift of emission wavelengths into the near-infrared (NIR) spectral region (ranging from 0.7 to 2 microns), which has greatly contributed to the latest advances in biomedical imaging and sensing. This book discusses merits of different contrast agents at nanoscale, and how their unique chemical and structural properties lead to the emission and interaction of light within the NIR window. Both the NIR-emitting materials and various surface modification strategies governing their interactions with the biological system at the “nano” level are discussed. Furthermore, different experimental techniques and protocols for NIR-light-based in vivo imaging and sensing are addressed to shed light on further understanding of the advantages and limitations of each category of these nanoprobes. Assembles the state of the art heretofore appearing in scientific literature into a comprehensive, multi-perspective guidebook on near infrared-emitting nanomaterials in an assortment of biomedical applications; Explains the physical, chemical, and biological phenomena underlying near infrared-emitting nanomaterials for biomedical applications; Presents conceptual and experimental approaches surrounding a unique spectral range of light emission from nanosized contrast agents, while offering a clear explanation of basic and general phenomena regarding the interaction between light and biological tissues, such as absorption, scattering and autofluorescence.
Biomedical Applications of Graphene and 2D Nanomaterials provides a much-needed reference on the biomedical applications of 2D nanomaterials, as well as theoretical knowledge on their structure, physicochemical properties and biomedical applications. Chapters are dedicated to growth areas, such as size and shape-dependent chemical and physical properties and applications, such as in diagnostic and therapeutic products. The book also discusses the concept, development and preclinical studies of 2D nanomaterials-based biomedical tools, such as biosensors, artificial organs and photomedicine. Case studies and reports form the core of the book, making it an ideal resource on potential applications in biomedical science and engineering. This timely resource for scientists and engineers in this rapidly advancing field features contributions from over 30 leaders who address advanced methods and strategies for controlling the physical-chemical properties of 2D nanomaterials, along with expert opinions on a range of 2D nanomaterials that have therapeutic and diagnostic applications. - Presents advanced methods and strategies for controlling the physical-chemical properties of 2D nanomaterials - Provides state-of-the-art biomedical applications for 2D nanomaterials, including graphene and boron nitride - Includes key information from a broad selection of subject areas for researchers in both materials, engineering and medicine
Provides timely, comprehensive coverage of in vivo chemical reactions within live animals This handbook summarizes the interdisciplinary expertise of both chemists and biologists performing in vivo chemical reactions within live animals. By comparing and contrasting currently available chemical and biological techniques, it serves not just as a collection of the pioneering work done in animal-based studies, but also as a technical guide to help readers decide which tools are suitable and best for their experimental needs. The Handbook of In Vivo Chemistry in Mice: From Lab to Living System introduces readers to general information about live animal experiments and detection methods commonly used for these animal models. It focuses on chemistry-based techniques to develop selective in vivo targeting methodologies, as well as strategies for in vivo chemistry and drug release. Topics include: currently available mouse models; biocompatible fluorophores; radionuclides for radiodiagnosis/radiotherapy; live animal imaging techniques such as positron emission tomography (PET) imaging; magnetic resonance imaging (MRI); ultrasound imaging; hybrid imaging; biocompatible chemical reactions; ligand-directed nucleophilic substitution chemistry; biorthogonal prodrug release strategies; and various selective targeting strategies for live animals. -Completely covers current techniques of in vivo chemistry performed in live animals -Describes general information about commonly used live animal experiments and detection methods -Focuses on chemistry-based techniques to develop selective in vivo targeting methodologies, as well as strategies for in vivo chemistry and drug release -Places emphasis on material properties required for the development of appropriate compounds to be used for imaging and therapeutic purposes in preclinical applications Handbook of In Vivo Chemistry in Mice: From Lab to Living System will be of great interest to pharmaceutical chemists, life scientists, and organic chemists. It will also appeal to those working in the pharmaceutical and biotechnology industries.
Functional Nanomaterials Presents the most recent advances in the production and applications of various functional nanomaterials As new synthetic methods, characterization technologies, and nanomaterials (NMs) with novel physical and chemical properties are developed, researchers and scientists across disciplines need to keep pace with advancements in the dynamic field. Functional Nanomaterials: Synthesis, Properties, and Applications provides comprehensive coverage of fundamental concepts, synthetic methods, characterization technologies, device fabrication, performance evaluation, and both current and emerging applications. Contributions from leading scientists in academia and industry present research developments of novel functional nanomaterials including metal nanoparticles, two-dimensional nanomaterials, perovskite-based nanomaterials, and polymer-based nanomaterials and nanocomposites. Topics include metal-based nanomaterials for electrochemical water splitting, cerium-based nanostructure materials for electrocatalysis, applications of rare earth luminescent nanomaterials, metal complex nanosheets, and methods for synthesizing polymer nanocomposites. Provides readers with timely and accurate information on the development of functional nanomaterials in nanoscience and nanotechnology Presents a critical perspective of the design strategy, synthesis, and characterization of advanced functional nanomaterials Focuses on recent research developments in emerging areas with emphasis on fundamental concepts and applications Explores functional nanomaterials for applications in areas such as electrocatalysis, bioengineering, optoelectronics, and electrochemistry Covers a diverse range of nanomaterials, including carbonaceous nanomaterials, metal-based nanomaterials, transition metal dichalcogenides-based nanomaterials, semiconducting molecules, and magnetic nanoparticles Functional Nanomaterials is an invaluable resource for chemists, materials scientists, electronics engineers, bioengineers, and others in the scientific community working with nanomaterials in the fields of energy, electronics, and biomedicine.
This book introduces the latest advances made in both fundamental studies and potential applications of upconversion nanomaterials, particularly in the field of high-resolution in vitro bioanalysis and in vivo imaging. This book starts with the synthesis and characterization, and focuses on applications ranging from materials science to biology. Above all, it describes cutting-edge advances in upconversion nanophosphor (UCNP)-based applications in multiplexed encoding, guest delivery and release systems, photodynamic therapy (PDT), solar cells, photocatalysis and so on. The major barriers that currently prevent UCNPs from being used in mainstream applications are also presented in detail.
In the last two decades, several promising engineered nanomaterials that combine therapeutic features and imaging functionalities have been presented, but very few have arrived on the market. The purpose of this book is to collect and comprehensively discuss the advances in this current and exciting topic in order to promote and enhance its growth. In the first part, a general introduction about the main features of both organic and inorganic nanomaterials is provided. Then, the most promising and innovative applications for cancer treatment and diagnostic are introduced. In the second part, an analysis of the nanomaterials in the market for healthcare applications is presented. The issue of unwanted accumulation of metals in organisms after the designed action is then discussed. Finally, the most recent progresses in the design of nanomaterials that are able to escape from organisms after the selected action are comprehensively described, and the perspectives of this exciting field provided.
Nanomaterials offer great potential for effective tumor diagnosis and therapy combing diagnostic agents and therapeutic drugs into one platform. In this book, the most recent progress of main nanomaterials and their applications in tumor targeting theranostics is presented. It summarizes the recent advances of current principal nanomaterials in tumor theranostics, including magnetic nanomaterials, quantum dots, mesoporous silica nanoparticles, gold nanomaterials, polymeric nanosystem, carbon nanomaterials, lipopolyplex nanoparticles, microbubbles, upconversion nanomaterials and dendrimers. It will enable readers to get a more realistic understanding of both the advantages and limitations of nanomaterials for potential tumor targeting theranosis. The publication of this book will accelerate the spread of ideas that are currently trickling through the scientific literature. Also a greater understanding of the potential and challenge of nanomaterials for tumor targeting theranostics is highly anticipated for practical clinical use.