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Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series
Revised and Updated for the Gold Rush From one of the world’s most knowledgeable coin dealers–a former consultant to the Federal Trade Commission who is often quoted by the Wall Street Journal–comes a thorough update of the most-trusted consumer protection handbook to buying and selling rare and valuable coins. Illustrated with black-and-white photographs and a full-color insert, The Coin Collector’s Survival Manual, Seventh Edition is indispensable for seasoned collectors and novices alike. This substantially revised edition of the Coin Collector’s Survival Manual includes revised chapters that focus on legal and financial advice for buying and selling coins, and a new chapter on the most secure way to detect coins that have been "doctored." You will learn how to: • Avoid scams when buying and selling gold • Understand the new coin grading system • Detect altered, counterfeit, and doctored coins • Know how high gold and silver coins will climb in value • Buy coins through Internet auctions–and avoid the pitfalls • Safeguard and protect your coins from disaster ABOUT THE AUTHOR: Scott Travers, former vice president of the American Numismatic Association, was called the “preeminent consumer advocate in the numismatic field” by The New York Times. He is a contributor to all the leading coin publications and served as a coin valuation consultant to the Federal Trade Commission. He has been featured as a coin expert in Barron’s, Business Week, The WSJ, MSNBC and TODAY.
The award-winning title has now been revised to offer the most up-to-date information and consumer protection advice available.
PART SIX: ONCOLOGIC EMERGENCIES -- 40. Metabolic Emergencies -- 41. Structural Emergencies -- PART SEVEN: SURVIVORSHIP -- 42. Survivorship -- PART EIGHT: PALLIATIVE AND END-OF-LIFE CARE -- 43. Palliative and End-of-Life Care -- PART NINE: PROFESSIONAL PRACTICE -- 44. Evidence-Based Practice and Standards of Oncology Nursing -- 45. Education Process -- 46. Legal Issues -- 47. Ethical Issues -- 48. Professional Issues -- Answer Key
Get the most out of your OCN® Exam review with this helpful study tool! Corresponding to the chapters in The Core Curriculum for Oncology Nursing, 5th Edition, this definitive study guide endorsed by the Oncology Nursing Society covers the entire scope of practice for oncology nursing. It is based on the latest test blueprint for the OCN Exam, with more than 1,200 practice questions addressing all oncology topics, including the newest advances in cancer treatment and related nursing care. Prepare to succeed on your OCN Exam with this ONS-endorsed study resource! The definitive study guide for the OCN® Examination is developed in collaboration with, and endorsed by, the Oncology Nursing Society, the parent organization of the Oncology Nursing Certification Corporation (ONCC), which administers the OCN Examination. Coverage of the entire scope of oncology nursing care includes quality of life, protective mechanisms, gastrointestinal and urinary function, cardiopulmonary function, oncologic emergencies, the scientific basis for practice, health promotion, and professional performance. An answer key includes rationales for correct and incorrect responses. NEW! Revised and updated content reflects the latest OCN® Examination test blueprint and The Core Curriculum for Oncology Nursing, 5th Edition. NEW emphasis on application-level questions helps you apply your knowledge more effectively. NEW! Updates on cancer treatment and related nursing care include the most current and accurate information, preparing you for the OCN Exam and for expert clinical practice. NEW! Emphasis on QSEN competencies is designed to reduce errors in oncology nursing practice with a focus on safety and evidence-based practice, including a Safety Alert icon and a High-Alert Medication icon for cancer chemotherapy drugs.
The growth in chemotherapy has led to a great need for all those involved to be familiar with safe procedures based on best evidence-based practice. Practical Chemotherapy: a multidisciplinary guide is a comprehensive and straightforward guide describing over 70 widely used chemotherapy regimens, helping to make their prescription and administration safer and less problematic. Checklists throughout the book are specifically tailored for the needs of each professional group involved in treatment, and are intended to help prevent potentially serious mistakes that can occur. This book is unique in its practical emphasis and will be invaluable for doctors, pharmacists and nurses working in oncology and haematology.
This comprehensive guide is the perfect book for new coin collectors and experienced numismatists alike, featuring the most up-to-date information available about this fascinating hobby. Fully indexed with actual size photos of every regularly issued U.S. coin, this book gives you the essential information on grading, production, and much more!
**Selected for Doody's Core Titles® 2024 with "Essential Purchase" designation in Oncology** Find oncology information fast with this concise, all-in-one clinical reference! Mosby's Oncology Nursing Advisor, 3rd Edition uses a streamlined format to provide quick access to the most essential information on oncology nursing care. Evidence-based guidelines include topics such as the major cancers, principles of cancer management, and principles of symptom management, as well as oncologic emergencies, palliative care, and nursing practice considerations. This edition includes new information on cancer treatments, genetic risk, chemotherapy guidelines, and more. Written by a team of oncology nursing experts led by Susan Maloney-Newton, this book is ideal for use in any oncology nursing setting. - Detailed descriptions of more than 50 major cancer types provide essential information on incidence, etiology and risk factors, signs and symptoms, diagnostic workup, histology, staging, treatment, prognosis, and prevention. - Coverage of cancer management principles outlines a wide range of treatment and pharmacologic modalities, including surgery, chemotherapy, radiation therapy, hormonal therapy, immunotherapy, and complementary and alternative therapies. - Symptom management guidelines offer in-depth coverage of pathophysiology, signs and symptoms, assessment tools, lab and diagnostic tests, differential diagnoses, interventions, patient education, follow up care, and resources for more than 30 common symptoms associated with cancer and cancer treatments. - Essential information on oncologic emergencies and emergent issues prepares readers to respond quickly to structural, urologic, metabolic, and hematologic emergencies. - Section on palliative care and end-of-life issues offers helpful guidelines for dealing with topics related to survivorship, palliative care, the final hours of the cancer patient, and loss, grief, and bereavement. - NEW! Updated content reflects the latest evidence-based information, including cancer biology, cancer treatment modalities, the latest chemotherapy guidelines, and a stronger emphasis on oral agents. - NEW! New content addresses the concept of "previvorship," the concept of coping with a documented genetically linked high cancer risk. - NEW! Enhanced content on health disparities, diversity and inclusion, and transgender considerations equips oncology nurses with essential information to promote health equity. - NEW! Key recommendations of the 2020-2030 Future of Nursing Report are integrated into the Nursing Practice Considerations section. - NEW! Content on the impact of the COVID pandemic includes delayed diagnosis and treatment and the impact of COVID sequelae on the health of patients with cancer. - NEW! Added content on palliative care is included in an expanded Pain chapter. - NEW! Full-color design and additional illustrations make it easier to use the book and to understand concepts. - NEW! Pulmonary Symptoms chapter now includes cough, dyspnea, and pleural effusion content.
This unique volume traces the critically important pathway by which a "molecule" becomes an "anticancer agent. " The recognition following World War I that the administration of toxic chemicals such as nitrogen mustards in a controlled manner could shrink malignant tumor masses for relatively substantial periods of time gave great impetus to the search for molecules that would be lethal to specific cancer cells. Weare still actively engaged in that search today. The question is how to discover these "anticancer" molecules. Anticancer Drug Development Guide: Preclinical Screening, Clinical Trials, and Approval, Second Edition describes the evolution to the present of preclinical screening methods. The National Cancer Institute's high-throughput, in vitro disease-specific screen with 60 or more human tumor cell lines is used to search for molecules with novel mechanisms of action or activity against specific phenotypes. The Human Tumor Colony-Forming Assay (HTCA) uses fresh tumor biopsies as sources of cells that more nearly resemble the human disease. There is no doubt that the greatest successes of traditional chemotherapy have been in the leukemias and lymphomas. Since the earliest widely used in vivo drug screening models were the murine L 1210 and P388 leukemias, the community came to assume that these murine tumor models were appropriate to the discovery of "antileukemia" agents, but that other tumor models would be needed to discover drugs active against solid tumors.