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Mind & Membrain is a book that not only reveals the 'missing link' between head impacts, mental health issues and early onset dementia but also offers a new approach to mental health diagnosis and treatment. It will interest patients, carers and practitioners across the whole field of mental health. The book begins with the link between head impacts and mental health issues, and early onset dementia. The statistics are well documented and the link is now headline news for sports such as rugby and football. Yet while knocks to the head of all kinds are commonplace and the consequences for mental health are now recognised, the link remains poorly understood. No one so far appears to have grasped the crucial role of the medically neglected dura membrane that lines the skull, envelops the brain and controls the vital irrigation system of the cranium. “Membrain disorder” gives a name to a common but typically undiagnosed condition where the skull is impacted, the dura responds, and – without preventive treatment – the brain and thus the patient’s mental health are impaired, both short and long term. The book, uniquely, explains how membrain disorder can be diagnosed and then successfully treated by a hands-on approach, without drugs or surgery. The book then addresses the current crisis in mental health diagnosis and treatment. Rather than lament the situation, this book offers a solution: an original model for mental health diagnosis. Drawing on complexity theory and biology, the approach generates a practical ‘road map’ guiding a practitioner to discover the dimension of origin of a mental health issue (rather than seek the closest match to the symptoms in the quasi-official doctors’ diagnostical manual, DSM-5). Similar symptoms can have completely different origins, ranging from microscopic molecular imbalances to society-level pressures. With the dimension of origin identified, an effective treatment can be implemented. The book will interest doctors, therapists, manual practitioners and others and give hope to mental health patients, their loved ones and their carers, especially those struggling to find a solution for problems that respond neither to drugs nor talking therapies. Mind & Membrain is written for the lay person and includes personal case histories that bring the topic alive.
The World Health Organization in 2004 estimated approximately 1.1 billion people did not have access to clean water and that 35% of Third World residents died from water-borne illnesses. While the situation is grim, recent advances strongly indicate that many of the current water quality problems can be addresses – and potentially resolved – using nanotechnology.Nanotechnology is already having a dramatic impact on research in water quality and Nanotechnology Applications for Clean Water highlights both the challenges and the opportunities for nanotechnology to positively influence this area of environmental protection.Here you will find detailed information on breakthroughs, cutting edge technologies, current research, and future trends that may affect acceptance of widespread applications. The first four parts of the book cover specific topics including using nanotechnology for clean drinking water in both large scale water treatment plants and in point-of-use systems. For instance, recent advances show that many of the current problems involving water quality can be addressed using nanosorbents, nanocatalysts, bioactive nanoparticles, nanostructured catalytic membranes, and nanoparticle enhanced filtration. The book also discusses existing technologies and future potential for groundwater remediation, pollution prevention, and sensors. The final part discusses the inherent societal implications that may affect acceptance of widespread applications. Over 80 leading experts from around the world share their wealth of knowledge in this truly unique reference. Institutions such as Center for the Purification of Water and Systems (Univ. of Illinois at Urbana-Champaign); UCLA Water Technology Center; Carnegie Mellon University, University of Kentucky; The University of Western Ontario; Pacific Northwest National Laboratory; National Institute for Advanced Industrial Science and Technology (Japan), Munasinghe Institute for Development (Sri Lanka) and the Woodrow Wilson Center for Scholars are just a few of the knowledge centers represented in this book. Water quality is a serious, global issue in which government bodies and scientific communities face many challenges in ensuring clean water is available to everyone. Nanotechnology is already showing dramatic results, and this book is an attempt to share current technologies and future possibilities in reaching this goal. From the Foreword:"Researchers and practitioners may find in this volume, key challenges regarding clean water resources. The presentations may crystallize new research and education programs." - Mihail Roco, U.S. National Science Foundation and U.S. Nanotechnology Initiative - Contributors from the US, India, Canada, Japan, UK, Sri Lanka, and South Africa - Provides detailed information on breakthroughs, cutting edge technologies, current research, and future trends that may affect acceptance of widespread applications - Covers specific topics including using nanotechnology for clean drinking water in both large scale water treatment plants and in point-of-use systems - Discusses existing technologies and future potential for groundwater remediation, pollution prevention, and sensors - Highlights both the challenges and the opportunities for nanotechnology to positively influence this area of environmental protection
This book mainly focuses on key aspects of biomembranes that have emerged over the past 15 years. It covers static and dynamic descriptions, as well as modeling for membrane organization and shape at the local and global (at the cell level) scale. It also discusses several new developments in non-equilibrium aspects that have not yet been covered elsewhere. Biological membranes are the seat of interactions between cells and the rest of the world, and internally, they are at the core of complex dynamic reorganizations and chemical reactions. Despite the long tradition of membrane research in biophysics, the physics of cell membranes as well as of biomimetic or synthetic membranes is a rapidly developing field. Though successful books have already been published on this topic over the past decades, none include the most recent advances. Additionally, in this domain, the traditional distinction between biological and physical approaches tends to blur. This book gathers the most recent advances in this area, and will benefit biologists and physicists alike.
quark >you mean my body has got tubes up its nose for nothingnot now ... no ... because the experiment ... e.a.r.t.h... existsat least that's some sort of relief
A compelling investigation into the relationships between our biological past and cultural progress, "Cells to Civilizations" presents a remarkable story of living change.
Biological membranes provide the fundamental structure of cells and viruses. Because much of what happens in a cell or in a virus occurs on, in, or across biological membranes, the study of membranes has rapidly permeated the fields of biology, pharmaceutical chemistry, and materials science. The Structure of Biological Membranes, Third Edition provides readers with an understanding of membrane structure and function that is rooted in the history of the field and brought to the forefront of current knowledge. The first part of the book focuses on the fundamentals of lipid bilayers and membrane proteins. Three introductory chapters supply those new to the field with the tools and conceptual framework with which to approach the state-of-the-art chapters that follow. The second part of the book presents in-depth analyses of focused subjects within the study of membranes, covering topics that include: Phase behavior of lipid bilayers Lipid bilayers as an isolated structure Cholesterol’s role in cell biology Lateral organization of membranes The role of membrane lipids in initial membrane protein folding Membrane protein synthesis and assembly of oligomeric membrane proteins Membrane protein stability with relationships to function and protein turnover Membrane protein function using a transport protein Interactions between membrane proteins and membrane lipids A final chapter pulls together many of the topics, examining in detail the complexity inherent in the synthesis and assembly of lipids and proteins in mitochondrial membranes. With contributions from leading researchers, this completely revised and updated third edition reflects recent advances in the field of biological membranes. It offers a valuable resource for students, as well as structural biologists, biophysicists, cell biologists, biochemists, and researchers in the pharmaceutical and biotechnology industries. What’s New in This Edition: Three accessible chapters introduce students to the field of biological membranes Completely revised and updated chapters present current topics in membrane research
This book describes the structures and functions of active protein filaments, found in bacteria and archaea, and now known to perform crucial roles in cell division and intra-cellular motility, as well as being essential for controlling cell shape and growth. These roles are possible because the cytoskeletal and cytomotive filaments provide long range order from small subunits. Studies of these filaments are therefore of central importance to understanding prokaryotic cell biology. The wide variation in subunit and polymer structure and its relationship with the range of functions also provide important insights into cell evolution, including the emergence of eukaryotic cells. Individual chapters, written by leading researchers, review the great advances made in the past 20-25 years, and still ongoing, to discover the architectures, dynamics and roles of filaments found in relevant model organisms. Others describe one of the families of dynamic filaments found in many species. The most common types of filament are deeply related to eukaryotic cytoskeletal proteins, notably actin and tubulin that polymerise and depolymerise under the control of nucleotide hydrolysis. Related systems are found to perform a variety of roles, depending on the organisms. Surprisingly, prokaryotes all lack the molecular motors associated with eukaryotic F-actin and microtubules. Archaea, but not bacteria, also have active filaments related to the eukaryotic ESCRT system. Non-dynamic fibres, including intermediate filament-like structures, are known to occur in some bacteria.. Details of known filament structures are discussed and related to what has been established about their molecular mechanisms, including current controversies. The final chapter covers the use of some of these dynamic filaments in Systems Biology research. The level of information in all chapters is suitable both for active researchers and for advanced students in courses involving bacterial or archaeal physiology, molecular microbiology, structural cell biology, molecular motility or evolution. Chapter 3 of this book is open access under a CC BY 4.0 license.
From molecular motors to bacteria, from crawling cells to large animals, active entities are found at all scales in the biological world. Active matter encompasses systems whose individual constituents irreversibly dissipate energy to exert self-propelling forces on their environment. Over the past twenty years, scientists have managed to engineer synthetic active particles in the lab, paving the way towards smart active materials. This book gathers a pedagogical set of lecture notes that cover topics in nonequilibrium statistical mechanics and active matter. These lecture notes stem from the first summer school on Active Matter delivered at the Les Houches school of Physics. The lectures covered four main research directions: collective behaviours in active-matter systems, passive and active colloidal systems, biophysics and active matter, and nonequilibrium statistical physics--from passive to active.
Nanotechnology is already having a dramatic impact on improving water quality and the second edition of Nanotechnology Applications for Clean Water highlights both the challenges and the opportunities for nanotechnology to positively influence this area of environmental protection. This book presents detailed information on cutting-edge technologies, current research, and trends that may impact the success and uptake of the applications. Recent advances show that many of the current problems with water quality can be addressed using nanosorbents, nanocatalysts, bioactive nanoparticles, nanostructured catalytic membranes, and nanoparticle enhanced filtration. The book describes these technologies in detail and demonstrates how they can provide clean drinking water in both large scale water treatment plants and in point-of-use systems. In addition, the book addresses the societal factors that may affect widespread acceptance of the applications. Sections are also featured on carbon nanotube arrays and graphene-based sensors for contaminant sensing, nanostructured membranes for water purification, and multifunctional materials in carbon microspheres for the remediation of chlorinated hydrocarbons. - Addresses both the technological aspects of delivering clean water supplies and the societal implications that affect take-up - Details how the technologies are applied in large-scale water treatment plants and in point-of-use systems - Highlights challenges and the opportunities for nanotechnology to positively influence this area of environmental protection
The soul-searching poems in Larry Dunn's debut collection, A Beanie and A Cup of Tea, invite readers into a deeply personal journey that explores the mystery of life and death, the beauty of words as gift, and the power of sustaining love not fully known before the loss of his son, Seth. Both introspective and transparent, Dunn writes with an unflinching style about the realities of unimaginable loss, his willingness to embrace the unknowable, and his renewed commitment to cherish life and those he loves. In an honest portrayal of what it means to sit with the pain of loss, Dunn searches for ways to stay connected to his son within the "thin spaces" of these poems, "where mystery is / cloaked in beauty / and the line between / heaven and earth / collapses into love." A Beanie and A Cup of Tea invites the reader into these spaces, extending a knowing embrace and giving voice to those whose lives are shaped by grief.