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Over the last two decades, molecular genetics and brain imaging have guided efforts to find the causes of schizophrenia. It is becoming increasingly clear that many genes are involved in schizophrenia and that they interact with other factors in very complex ways, which have not yet been elucidated. Neuroimaging techniques have allowed scientists and physicians to examine brain structure, function, and chemistry in living patients with schizophrenia but results so far have been disappointing. No two patients seem to share exactly the same combination of clinical symptoms or physical findings. Yet all have the syndrome recognized as schizophrenia. The author of this accessible, well-written book argues that it is time to set aside the search for a single cause of schizophrenia and focus on the disease's final common pathway. He highlights clues from a wide range of research, including neurotransmitter, psychophysiological, and brain imaging studies. He then describes possibilities for the final common pathway at an understandable level in the context of what is already known about schizophrenia. While there are no preferred models of schizophrenia, a pattern is emerging which implicates those structures in the brain known to be important in integrating perception, cognition, and affect. A better understanding of these processes will be critical for developing more effective treatments. This book will help advance that effort. It will be of great value to psychiatrists, psychologists, neurologists, neuroimagers, and basic scientists working in the field of schizophrenia research, and to their students and trainees. It will also be of interest to clinicians and scientists concerned with other neuropsychiatric disorders, and to the families of those diagnosed with schizophrenia.
I personally know some people in my immediate circles who have been diagnosed with schizophrenia, so I decided to analyze this disorder and really align the most important things you need to know about it. I don’t know what prompted you to pick up this book; whether you already know people with a schizophrenic mind or just got curious, just in case you do meet someone who is dealing with this disorder. Let me assure you that schizophrenia is prevalent enough that you’ll be confronted with an individual or two at some point in life, and that is does help to learn more about it. With this book, you’ll deepen your understanding, and you’ll be more inclined to comprehend the complicated processes in a person’s mind who innocently gets haunted by some of the difficult symptoms of schizophrenia. The information in this book is correct and accurate, and you will find that it will make sense, especially when you observe these symptoms in an individual you know or meet. Additionally, I will provide possible solutions for handling the disorder. As with many disorders, every person is different, and some solutions may only minimize the negative effects of the brain’s malfunctioning. Others may help you work “miracles” as you notice significant process in the individual’s happiness and fulfilment in life. I encourage you to read through the pointers and notes in this comprehensive guide to understanding schizophrenia.
“The most important book about schizophrenia in decades, and perhaps ever…a total game-changer.” —Sylvia Nasar, author of A Beautiful Mind A comprehensive, deeply researched, and highly readable portrait of schizophrenia—its history, its various manifestations, and how today’s treatments have promising and often lifesaving potential. This “incredibly captivating” (Siddhartha Mukherjee, author of The Emperor of All Maladies) portrait of schizophrenia, the most malignant and mysterious mental illness, by renowned psychiatrist Jeffrey Lieberman, interweaves cultural and scientific history with dramatic patient profiles and clinical experiences to impart a revolutionary message of hope. For the first time in history, we can effectively treat schizophrenia, limiting its disabling effects—and we’re on the verge of being able to prevent the disease’s onset entirely. Drawing on his four-decade career, Dr. Jeffrey Lieberman expertly illuminates the past, present, and future of this historically dreaded and devastating illness. Interweaving history, science, and policy with personal anecdotes and clinical cases, Malady of the Mind is a rich, illuminating experience written in accessible, fluid prose. From Dr. Lieberman’s vantage point at the pinnacle of academic psychiatry, informed by extensive research experience and clinical care of thousands of patients, he explains how the complexity of the brain, the checkered history of psychiatric medicine, and centuries of stigma combined with misguided legislation and health care policies have impeded scientific advances and clinical progress. Despite this, there is reason for optimism: by offering evidence-based treatments that combine medication with psychosocial services and principles learned from the recovery movement, doctors can now effectively treat schizophrenia by diagnosing patients at a very early stage, achieving a mutually respectful therapeutic alliance, and preventing relapse, thus limiting the progression of the illness. Even more promising, decades of work on diagnosis, detection, and early intervention have pushed scientific progress to the cusp of prevention—meaning that in the near future, doctors may be able to prevent the onset of this disorder. A must-read for those interested in medical history, psychology, and those whose lives have been affected by schizophrenia, this “penetrating, important” (Andrew Solomon, author of Noonday Demon) work offers a comprehensive scientific portrait, crucial insights, sound advice for families and friends, and most importantly, hope for those sufferers now and future generations.
This is a classic edition of Christopher Frith’s award winning book on cognitive neuropsychology and schizophrenia, which now includes a new introduction from the author. The book explores the signs and symptoms of schizophrenia using the framework of cognitive neuropsychology, looking specifically at the cognitive abnormalities that underlie these symptoms. The book won the British Psychological Society book award in 1996, and is now widely seen as a classic in the field of brain disorders. The new introduction sees the author reflect on the influence of his research and the subsequent developments in the field, more than 20 years since the book was first published.
The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."
This book covers recent advances in the understanding of brain structure, function and disorders based on the fundamental principles of physics. It covers a broad range of physical phenomena occurring in the brain circuits for perception, cognition, emotion and action, representing the building blocks of the mind. It provides novel insights into the devastating brain disorders of the mind such as schizophrenia, dementia, autism, aging or addictions, as well as into the new devices for brain repair. The book is aimed at basic researchers in the fields of neuroscience, physics, biophysics and clinicians in the fields of neurology, neurosurgery, psychology, psychiatry.
This book explores the relationship between schizophrenia and common sense. It approaches this theme from a multidisciplinary perspective. Coverage features contributions from phenomenology, cognitive neuroscience, philosophy of mind, psychology, and social cognition. The contributors address the following questions: How relevant is the loss of common sense in schizophrenia? How can the study of schizophrenia contribute to the study of common sense? How to understand and explain this loss of common sense? They also consider: What is the relationship of practical reasoning and logical formal reasoning with schizophrenia? What is the relationship between the person with a diagnosis of schizophrenia and social values? Chapters examine such issues as rationality, emotions, self, and delusion. In addition, one looks at brain structure and neurotransmission. Others explore phenomenological and Wittgensteinian theories. The book features papers from the Schizophrenia and Common Sense International Workshop, held at New University of Lisbon, November 2015. It offers new insights into this topic and will appeal to researchers, students, as well as interested general readers.
What is schizophrenia? This is one of the most controversial questions in psychiatry and mental health research; however, in the last twenty years, there have been significant advances in our understanding of the topic. This book provides a balanced, comprehensive and up-to-date overview of the neuropathology of schizophrenia and its interpretation, covering the latest evidence derived from all fields of research, from brain scans to microscopy. The authors include many of the foremost international authorities in this rapidly developing field.