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New insights into one of the world's most common infectious diseases Chlamydiae are obligate intracellular bacteria that cause one of the most common sexually transmitted infectious diseases in the world. The infection disproportionately impacts women and the highest prevalence of infection is found in adolescents. Most chlamydial infections are asymptomatic. Untreated infections are sources of further spread of infection and can lead to serious consequences including pelvic inflammatory disease, infertility and chronic pelvic pain. Chlamydial infections also increase a person's susceptibility to HIV and other STDs. Featuring contributions by internationally recognized experts in epidemiology, infectious disease research and chlamydial biology, this book provides up-to-date reviews from a clinical and public health perspective on chlamydia epidemiology and control programs, genomics and pathogenicity, diagnosis, treatment, host immune responses, and the latest on the search for an effective vaccine. Also included are chapters on the impact of chlamydial infection on specific populations such as the lesbian, gay, bisexual and transgender community, and an update on the outbreak in Europe of the invasive chlamydial infection, lymphogranuloma venereum or LGV. This comprehensive publication is intended for clinicians, public health workers and scientists with interest in sexually transmitted diseases, medical microbiology, infectious diseases and clinical research.
Containing nineteen chapters this comprehensive book is essential reading for every Chlamydia researcher.
First Published in 1988, this book offers a full, comprehensive guide into microbiology of Chlamydia and its relationship with our bodies. Carefully compiled and filled with a vast repertoire of notes, pictures, and references this book serves as a useful reference for Students of Medicine, and other practitioners in their respective fields.
The Atlas of Sexually Transmitted Diseases and AIDS, 4th Edition, by Drs. Stephen A. Morse, King K. Holmes, Adele A. Moreland, MD, and Ronald C. Ballard, provides you with an exclusive gallery of STD and AIDS images so you can better diagnose and treat these diseases. Approximately 1,100 unique images – most in full color and 30% new to this edition – depict the clinical signs associated with each type of infection. You’ll also find expert guidance on new vaccines, screening techniques, treatment guidelines, and best practices in the field. Get expert advice on the tests available to reach a definitive diagnosis and review therapeutic options, treatment guidelines, prevention strategies, and management of complications. Access appendices on the selection and evaluation of diagnostic tests, quality control, and test technologies. Effectively diagnose all types of STDs and HIV/AIDS with approximately 1,100 images—most in full color and more than 30% new to this edition―that depict the epidemiology as well as the clinical manifestations of these diseases. Effectively utilize new vaccines for HPV and Hepatitis B, new screening tests for Chlamydia, new drugs under development, new treatment guidelines and best practices in HIV screening, and much more.
Chlamydiae are a group of obligate intracellular microorganisms with a homogeneous group-specific antigenic structure, and a unique mode of development. The infections caused by them are unprecedented and wide-spread throughout the world, including a broad range of hosts among domestic and animal species and humans, and a variety of clinical manifestations. The uniqueness of chlamydia pathology consists mainly in the fact that the agents of the individual diseases are so close in their biological properties that they are represented only by the single genus Chlamydia, which includes all currently recognized species.Although chlamydiae and chlamydial infections were discovered a long time ago, they are still under-researched and relatively unknown to broad circles of microbiologists, virologists, epidemiologists and clinicians. A number of issues relating to molecular biology, pathogenesis, mechanisms of Chlamydia development and their interactions with cells, as well as their genetic conditioning and regulation, remain unclear. The same is true for ambiguities, problems and contradictions related to epidemiology, diagnostic approaches, immunity and vaccines. Based on scientific facts and the analysis of literature, and the experience of the author, Chlamydiae and Chlamydial Infections attempts to shed light on the cited problems, in terms of modern microbiology, cell biology and molecular biology. The scientific topics discussed include:• Biological, morphological and antigenic properties of Chlamydia spp• Genes, genomic structure and genetic regulations• Conventional diagnostic methods and examinations• Detection and differentiation of Chlamydia organisms by DNA detection systems• Clinical forms and manifestations and drug therapy• Pathology• Epidemiological peculiarities of Chlamydia ─ induced diseases in animals and humans• Immunity and vaccines
Medical Microbiology Illustrated presents a detailed description of epidemiology, and the biology of micro-organisms. It discusses the pathogenicity and virulence of microbial agents. It addresses the intrinsic susceptibility or immunity to antimicrobial agents. Some of the topics covered in the book are the types of gram-positive cocci; diverse group of aerobic gram-positive bacilli; classification and clinical importance of erysipelothrix rhusiopathiae; pathogenesis of mycobacterial infection; classification of parasitic infections which manifest with fever; collection of blood for culture and control of substances hazardous to health. The classification and clinical importance of neisseriaceae is fully covered. The definition and pathogenicity of haemophilus are discussed in detail. The text describes in depth the classification and clinical importance of spiral bacteria. The isolation and identification of fungi are completely presented. A chapter is devoted to the laboratory and serological diagnosis of systemic fungal infections. The book can provide useful information to microbiologists, physicians, laboratory scientists, students, and researchers.
This comprehensive, authoritative treatise covers all aspects of mucosal vaccines including their development, mechanisms of action, molecular/cellular aspects, and practical applications. The contributing authors and editors of this one-of-a-kind book are very well known in their respective fields. Mucosal Vaccines is organized in a unique format in which basic, clinical, and practical aspects of the mucosal immune system for vaccine development are described and discussed. This project is endorsed by the Society for Mucosal Immunology. - Provides the latest views on mucosal vaccines - Applies basic principles to the development of new vaccines - Links basic, clinical, and practical aspects of mucosal vaccines to different infectious diseases - Unique and user-friendly organization
Understand the clinically important aspects of microbiology with this full-color review Includes more than 20 case studies The twenty-seventh edition of Jawetz, Melnick & Adelberg’s Medical Microbiology delivers a concise, up-to-date overview of the roles microorganisms play in human health and illness. Linking fundamental principles with the diagnosis and treatment of microbial infections, this classic text has been updated throughout to reflect the tremendous expansion of medical knowledge afforded by molecular mechanisms, advances in our understanding of microbial pathogenesis, and the discovery of novel pathogens. Along with brief descriptions of each organism, you will find vital perspectives on pathogenesis, diagnostic laboratory tests, clinical findings, treatment, and epidemiology. The book also includes an entire chapter of case studies that focuses on differential diagnosis and management of microbial infections. Here’s why Jawetz, Melnick & Adelberg’s Medical Microbiology is essential for USMLE review: 650+ USMLE-style review questions 300+ informative tables and illustrations 23 case studies to sharpen you differential diagnosis and management skills An easy-to-access list of medically important microorganisms Coverage that reflects the latest techniques in laboratory and diagnostic technologies Full-color images and micrographs Chapter-ending summaries Chapter concept checks Jawetz, Melnick & Adelberg’s Medical Microbiology introduces you to basic clinical microbiology through the fields of bacteriology, virology, mycology, and parasitology, giving you a thorough yet understandable review of the discipline.
Multidisciplinary collection of essays on the relationship of infertility and the "historic" STIs--gonorrhea, chlamydia, and syphilis--producing surprising new insights in studies from across the globe and spanning millennia.