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This book applies methods from nonlinear dynamics to problems in neuroscience. It uses modern mathematical approaches to understand patterns of neuronal activity seen in experiments and models of neuronal behavior. The intended audience is researchers interested in applying mathematics to important problems in neuroscience, and neuroscientists who would like to understand how to create models, as well as the mathematical and computational methods for analyzing them. The authors take a very broad approach and use many different methods to solve and understand complex models of neurons and circuits. They explain and combine numerical, analytical, dynamical systems and perturbation methods to produce a modern approach to the types of model equations that arise in neuroscience. There are extensive chapters on the role of noise, multiple time scales and spatial interactions in generating complex activity patterns found in experiments. The early chapters require little more than basic calculus and some elementary differential equations and can form the core of a computational neuroscience course. Later chapters can be used as a basis for a graduate class and as a source for current research in mathematical neuroscience. The book contains a large number of illustrations, chapter summaries and hundreds of exercises which are motivated by issues that arise in biology, and involve both computation and analysis. Bard Ermentrout is Professor of Computational Biology and Professor of Mathematics at the University of Pittsburgh. David Terman is Professor of Mathematics at the Ohio State University.
The new edition of Fundamentals of Computational Neuroscience build on the success and strengths of the first edition. Completely redesigned and revised, it introduces the theoretical foundations of neuroscience with a focus on the nature of information processing in the brain.
During his long and continuing scholarly career, Patrick Suppes contributed significantly both to the sciences and to their philosophies. The volume consists of papers by an international group of Suppes colleagues, collaborators, and students in many of the areas of his expertise, building on or adding to his insights. Michael Friedman offers an overview of Suppes accomplishments and of his unique perspective on the relation between science and philosophy. Paul Humphreys, Stephen Hartmann, and Tom Ryckman present essays in the philosophy of physics. Jens-Erik Fenstad, Harvey Friedman, and Jaako Hintikka consider problems in the foundations of mathematics, while the late Duncan Luce, Jean-Claude Falmagne, Brian Skyrms, and Hannes Leitgeb have contributed essays in theory of measurement, decision theory and probability. Foundations of economics and political theory are addressed by Adolfo Garcia de la Sienra, Russell Hardin, and Kenneth Arrow. Psychology, language, and philosophy of language are addressed by Elizabeth Loftus, Anne Fagot-Largeault, Willem Levelt, Dagfinn Follesdal, and Marcos Perreau-Guimares and some of Suppes most recent research in neurobiology is addressed in essays by Colleen Crangle, Acadio de Barros and Claudio Carvalhes. Finally Nancy Cartwright and Alexandre Marcelles consider the alignment (or misalignment) of method and policy. Each of the essays is accompanied by a response from Suppes."
The study of mathematical cognition and the ways in which the ideas of space, time and number are encoded in brain circuitry has become a fundamental issue for neuroscience. How such encoding differs across cultures and educational level is of further interest in education and neuropsychology. This rapidly expanding field of research is overdue for an interdisciplinary volume such as this, which deals with the neurological and psychological foundations of human numeric capacity. A uniquely integrative work, this volume provides a much needed compilation of primary source material to researchers from basic neuroscience, psychology, developmental science, neuroimaging, neuropsychology and theoretical biology. The first comprehensive and authoritative volume dealing with neurological and psychological foundations of mathematical cognition Uniquely integrative volume at the frontier of a rapidly expanding interdisciplinary field Features outstanding and truly international scholarship, with chapters written by leading experts in a variety of fields
Mathematics for Neuroscientists, Second Edition, presents a comprehensive introduction to mathematical and computational methods used in neuroscience to describe and model neural components of the brain from ion channels to single neurons, neural networks and their relation to behavior. The book contains more than 200 figures generated using Matlab code available to the student and scholar. Mathematical concepts are introduced hand in hand with neuroscience, emphasizing the connection between experimental results and theory. - Fully revised material and corrected text - Additional chapters on extracellular potentials, motion detection and neurovascular coupling - Revised selection of exercises with solutions - More than 200 Matlab scripts reproducing the figures as well as a selection of equivalent Python scripts
with simulations and illustrations by Richard Gray Problem solving is an indispensable part of learning a quantitative science such as neurophysiology. This text for graduate and advanced undergraduate students in neuroscience, physiology, biophysics, and computational neuroscience provides comprehensive, mathematically sophisticated descriptions of modern principles of cellular neurophysiology. It is the only neurophysiology text that gives detailed derivations of equations, worked examples, and homework problem sets (with complete answers). Developed from notes for the course that the authors have taught since 1983, Foundations of Cellular Neurophysiology covers cellular neurophysiology (also some material at the molecular and systems levels) from its physical and mathematical foundations in a way that is far more rigorous than other commonly used texts in this area.
Learn to use computational modelling techniques to understand the nervous system at all levels, from ion channels to networks.
This book is intended as a text for a one-semester course on Mathematical and Computational Neuroscience for upper-level undergraduate and beginning graduate students of mathematics, the natural sciences, engineering, or computer science. An undergraduate introduction to differential equations is more than enough mathematical background. Only a slim, high school-level background in physics is assumed, and none in biology. Topics include models of individual nerve cells and their dynamics, models of networks of neurons coupled by synapses and gap junctions, origins and functions of population rhythms in neuronal networks, and models of synaptic plasticity. An extensive online collection of Matlab programs generating the figures accompanies the book.
The nervous system of higher animals is very complex and highly nonlinear. among its many capabilities are making decisions and carrying out complex motor actions such as swimming. Nonlinear dynamical modelling can be used to understand and explain neural phenomena at many different levels, including - ion-currents and action potentials; short - and long - term memory; visual hallucinations; neural synchronization; motor control This book explores the mathematical principles by which brains generate spikes, make decisions, store memories, and control actions. It assumes a basic knowledge of calculus and develops the dynamical foundations of neuroscience using problem sets and computer simulations on the accompanying PC and Mac compatible MatLab disk.
MAGNETIC RESONANCE IMAGING Mathematical Foundations and Applications By Walter J. Schempp As magnetic resonance imaging (MRI) continues to transform medical diagnostics and the study of the brain, the necessity for a more precise description of this important clinical tool is increasingly evident. A mathematical understanding of MRI and the related imaging modalities of functional MRI and NMR spectroscopy can greatly improve many scientific and medical endeavors, from the quality of scans in the tomographic slices and their semantic interpretations to minimally invasive neurosurgery and research in cognitive neuroscience. Magnetic Resonance Imaging advances a coherent mathematical theory of MRI and presents for the first time a real-world application of non-commutative Fourier analysis. Emphasizing the interdisciplinary nature of clinical MRI, this book offers an intriguing look at the geometric principles underlying the quantum phenomena of biomedical research. Author Walter J. Schempp, widely respected among mathematicians and neuro-network scientists alike, includes in this lucid, readable text: * The historical and phenomenological aspects of NMR spectroscopy and clinical MRI * A mathematical approach to the structure-function problem in clinical MRI * Detailed descriptions of applications to medical diagnostics * Photographs illustrating the superior contrast and spatial resolution achieved by MRI * An extensive list of references. Magnetic Resonance Imaging introduces clinical and mathematical concepts gradually and deliberately, making the complex procedure of MRI accessible to professionals in all areas of neuroscience and neurology, as well as those in mathematics, engineering, radiology, and physics.