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The book includes articles from eminent international scientists discussing a wide spectrum of topics of current importance in mathematics and statistics and their applications. It presents state-of-the-art material along with a clear and detailed review of the relevant topics and issues concerned. The topics discussed include message transmission, colouring problem, control of stochastic structures and information dynamics, image denoising, life testing and reliability, survival and frailty models, analysis of drought periods, prediction of genomic profiles, competing risks, environmental applications and chronic disease control. It is a valuable resource for researchers and practitioners in the relevant areas of mathematics and statistics.
An accessible undergraduate textbook on the essential math concepts used in the life sciences The life sciences deal with a vast array of problems at different spatial, temporal, and organizational scales. The mathematics necessary to describe, model, and analyze these problems is similarly diverse, incorporating quantitative techniques that are rarely taught in standard undergraduate courses. This textbook provides an accessible introduction to these critical mathematical concepts, linking them to biological observation and theory while also presenting the computational tools needed to address problems not readily investigated using mathematics alone. Proven in the classroom and requiring only a background in high school math, Mathematics for the Life Sciences doesn't just focus on calculus as do most other textbooks on the subject. It covers deterministic methods and those that incorporate uncertainty, problems in discrete and continuous time, probability, graphing and data analysis, matrix modeling, difference equations, differential equations, and much more. The book uses MATLAB throughout, explaining how to use it, write code, and connect models to data in examples chosen from across the life sciences. Provides undergraduate life science students with a succinct overview of major mathematical concepts that are essential for modern biology Covers all the major quantitative concepts that national reports have identified as the ideal components of an entry-level course for life science students Provides good background for the MCAT, which now includes data-based and statistical reasoning Explicitly links data and math modeling Includes end-of-chapter homework problems, end-of-unit student projects, and select answers to homework problems Uses MATLAB throughout, and MATLAB m-files with an R supplement are available online Prepares students to read with comprehension the growing quantitative literature across the life sciences A solutions manual for professors and an illustration package is available
This monograph will provide an in-depth mathematical treatment of modern multiple test procedures controlling the false discovery rate (FDR) and related error measures, particularly addressing applications to fields such as genetics, proteomics, neuroscience and general biology. The book will also include a detailed description how to implement these methods in practice. Moreover new developments focusing on non-standard assumptions are also included, especially multiple tests for discrete data. The book primarily addresses researchers and practitioners but will also be beneficial for graduate students.
Mathematical Statistics with Applications in R, Second Edition, offers a modern calculus-based theoretical introduction to mathematical statistics and applications. The book covers many modern statistical computational and simulation concepts that are not covered in other texts, such as the Jackknife, bootstrap methods, the EM algorithms, and Markov chain Monte Carlo (MCMC) methods such as the Metropolis algorithm, Metropolis-Hastings algorithm and the Gibbs sampler. By combining the discussion on the theory of statistics with a wealth of real-world applications, the book helps students to approach statistical problem solving in a logical manner.This book provides a step-by-step procedure to solve real problems, making the topic more accessible. It includes goodness of fit methods to identify the probability distribution that characterizes the probabilistic behavior or a given set of data. Exercises as well as practical, real-world chapter projects are included, and each chapter has an optional section on using Minitab, SPSS and SAS commands. The text also boasts a wide array of coverage of ANOVA, nonparametric, MCMC, Bayesian and empirical methods; solutions to selected problems; data sets; and an image bank for students.Advanced undergraduate and graduate students taking a one or two semester mathematical statistics course will find this book extremely useful in their studies. - Step-by-step procedure to solve real problems, making the topic more accessible - Exercises blend theory and modern applications - Practical, real-world chapter projects - Provides an optional section in each chapter on using Minitab, SPSS and SAS commands - Wide array of coverage of ANOVA, Nonparametric, MCMC, Bayesian and empirical methods
This book constitutes an up-to-date account of principles, methods, and tools for mathematical and statistical modelling in a wide range of research fields, including medicine, health sciences, biology, environmental science, engineering, physics, chemistry, computation, finance, economics, and social sciences. It presents original solutions to real-world problems, emphasizes the coordinated development of theories and applications, and promotes interdisciplinary collaboration among mathematicians, statisticians, and researchers in other disciplines. Based on a highly successful meeting, the International Conference on Applied Mathematics, Modeling and Computational Science, AMMCS 2019, held from August 18 to 23, 2019, on the main campus of Wilfrid Laurier University, Waterloo, Canada, the contributions are the results of submissions from the conference participants. They provide readers with a broader view of the methods, ideas and tools used in mathematical, statistical and computational sciences.
The book provides a unique collection of in-depth mathematical, statistical, and modeling methods and techniques for life sciences, as well as their applications in a number of areas within life sciences. The book provides also with a range of new ideas that represent emerging frontiers in life sciences where the application of such quantitative methods and techniques is becoming increasingly important. Many areas within life sciences are becoming increasingly quantitative and the progress in those areas will be more and more dependent on the successful development of advanced mathematical, statistical and modelling methodologies and techniques. The state-of-the-art developments in such methodologies and techniques are scattered throughout research journals and hardly accessible to the practitioners in those areas. This book identifies a number of frontier areas where such methodologies and techniques have recently been developed and are to be published here for the first time, bringing substantial potential benefit to a range of applications in life sciences. In addition, the book contains several state-of-the-art surveys at the interface of mathematics and life sciences that would benefit a larger interdisciplinary community. It is aimed at researchers in academia, practitioners and graduate students who want to foster interdisciplinary collaborations required to meet the challenges at the interface of modern life sciences and mathematics.
Statistic: A Concise Mathematical Introduction for Students and Scientists offers a one academic term text that prepares the student to broaden their skills in statistics, probability and inference, prior to selecting their follow-on courses in their chosen fields, whether it be engineering, computer science, programming, data sciences, business or economics. The book places focus early on continuous measurements, as well as discrete random variables. By invoking simple and intuitive models and geometric probability, discrete and continuous experiments and probabilities are discussed throughout the book in a natural way. Classical probability, random variables, and inference are discussed, as well as material on understanding data and topics of special interest. Topics discussed include: • Classical equally likely outcomes • Variety of models of discrete and continuous probability laws • Likelihood function and ratio • Inference • Bayesian statistics With the growth in the volume of data generated in many disciplines that is enabling the growth in data science, companies now demand statistically literate scientists and this textbook is the answer, suited for undergraduates studying science or engineering, be it computer science, economics, life sciences, environmental, business, amongst many others. Basic knowledge of bivariate calculus, R language, Matematica and JMP is useful, however there is an accompanying website including sample R and Mathematica code to help instructors and students.
This book constitutes an up-to-date account of principles, methods, and tools for mathematical and statistical modelling in a wide range of research fields, including medicine, health sciences, biology, environmental science, engineering, physics, chemistry, computation, finance, economics, and social sciences. It presents original solutions to real-world problems, emphasizes the coordinated development of theories and applications, and promotes interdisciplinary collaboration among mathematicians, statisticians, and researchers in other disciplines. Based on a highly successful meeting, the International Conference on Applied Mathematics, Modeling and Computational Science, AMMCS 2019, held from August 18 to 23, 2019, on the main campus of Wilfrid Laurier University, Waterloo, Canada, the contributions are the results of submissions from the conference participants. They provide readers with a broader view of the methods, ideas and tools used in mathematical, statistical and computational sciences.
This is the only book that teaches all aspects of modern mathematical modeling and that is specifically designed to introduce undergraduate students to problem solving in the context of biology. Included is an integrated package of theoretical modeling and analysis tools, computational modeling techniques, and parameter estimation and model validation methods, with a focus on integrating analytical and computational tools in the modeling of biological processes. Divided into three parts, it covers basic analytical modeling techniques; introduces computational tools used in the modeling of biological problems; and includes various problems from epidemiology, ecology, and physiology. All chapters include realistic biological examples, including many exercises related to biological questions. In addition, 25 open-ended research projects are provided, suitable for students. An accompanying Web site contains solutions and a tutorial for the implementation of the computational modeling techniques. Calculations can be done in modern computing languages such as Maple, Mathematica, and MATLAB?.
The purpose of this volume is to present and discuss the many rich properties of the dynamical systems that appear in life science and medicine. It provides a fascinating survey of the theory of dynamical systems in biology and medicine. Each chapter will serve to introduce students and scholars to the state-of-the-art in an exciting area, to present new results, and to inspire future contributions to mathematical modeling in life science and medicine.