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The renowned physicist Emilio Segr� (1905-1989) left his memoirs to be published posthumously because, he said, "I tell the truth the way it was and not the way many of my colleagues wish it had been." This compelling autobiography offers a personal account of his fascinating life as well as candid portraits of some of this century's most important scientists, such as Enrico Fermi, E. O. Lawrence, and Robert Oppenheimer. Born in Italy to a well-to-do Jewish family, Segr� showed early signs of scientific genius--at age seven he began a notebook of physics experiments. He became Fermi's first graduate student in 1928 and contributed to the discovery of slow neutrons, and later was appointed director of the physics laboratory at the University of Palermo. While visiting the Radiation Laboratory at Berkeley in 1938, he learned that he had been dismissed from his Palermo post by Mussolini's Fascist regime. Lawrence then hired him to work on the cyclotron at Berkeley with Luis Alvarez, Edwin McMillan, and Glenn Seaborg. Segr� was one of the first to join Oppenheimer at Los Alamos, where he became a group leader on the Manhattan Project. His account of that mysterious enclave of scientists, all working feverishly to develop the atomic bomb before the Nazis did, includes his description of the first explosion at Alamogordo. Segr� writes movingly of the personal devastation wrought by the Nazis, his struggles with fellow scientists, and his love of nature. His book offers an intimate glimpse into a bygone era as well as a unique perspective on some of the most important scientific developments of this century.
Offering both in-depth analyses of specific films and overviews of the industry's output, Hollywood's Indian provides insightful characterizations of the depiction of the Native Americans in film. This updated edition includes a new chapter on Smoke Signals , the groundbreaking independent film written by Sherman Alexie and directed by Chris Eyre. Taken as a whole the essays explore the many ways in which these portrayals have made an impact on our collective cultural life.
In the late 1980s, it became painfully evident to the pharmaceutical industry that the old paradigm of drug discovery, which involved highly segmented drug - sign and development activities, would not produce an acceptable success rate in the future. Therefore, in the early 1990s a paradigm shift occurred in which drug design and development activities became more highly integrated. This new str- egy required medicinal chemists to design drug candidates with structural f- tures that optimized pharmacological (e. g. , high affinity and specificity for the target receptor), pharmaceutical (e. g. , solubility and chemical stability), bioph- maceutical (e. g. , cell membrane permeability), and metabolic/pharmacokinetic (e. g. , metabolic stability, clearance, and protein binding) properties. Successful implementation of this strategy requires a multidisciplinary team effort, incl- ing scientists from drug design (e. g. , medicinal chemists, cell biologists, en- mologists, pharmacologists) and drug development (e. g. , analytical chemists, pharmaceutical scientists, physiologists, and molecular biologists representing the disciplines of pharmaceutics, biopharmaceutics, and pharmacokinetics/drug metabolism). With this new, highly integrated approach to drug design now widely utilized by the pharmaceutical industry, the editors of this book have provided the sci- tific community with case histories to illustrate the nature of the interdisciplinary interactions necessary to successfully implement this new approach to drug d- covery. In the first chapter, Ralph Hirschmann provides a historical perspective of why this paradigm shift in drug discovery has occurred.
This book focuses on the implementation of Artificial Intelligence in Business, Education and Healthcare, It includes research articles and expository papers on the applications of Artificial Intelligence on Decision Making, Entrepreneurship, Social Media, Healthcare, Education, Public Sector, FinTech, and RegTech. It also discusses the role of Artificial Intelligence in the current COVID-19 pandemic, in the health sector, education, and others. It also discusses the impact of Artificial Intelligence on decision-making in vital sectors of the economy.
"Themed spaces have, at their foundation, an overarching narrative, symbolic complex, or story that drives the overall context of their spaces. Theming, in some very unique ways, has expanded beyond previous stereotypes and oversimplifications of culture and place to now consider new and often controversial topics, themes, and storylines."--Publisher's website.
Light Alloys Directory and Databook is a world-wide directory of the properties and suppliers of light alloys used in, or proposed for, numerous engineering applications. Alloys covered will include aluminium alloys, magnesium alloys, titanium alloys, beryllium. For the metals considered each section will consist of: a short introduction; a table comparing basic data and a series of comparison sheets. The book will adopt standardised data in order to help the reader in finding and comparing different materials and identifying the required information. All comparison sheets are cross-referenced, so that the user will be able to locate data on a specific product or compare properties easily. The book is designed to complement the existing publications on high performance materials.