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The Pocket Book is for use by doctors nurses and other health workers who are responsible for the care of young children at the first level referral hospitals. This second edition is based on evidence from several WHO updated and published clinical guidelines. It is for use in both inpatient and outpatient care in small hospitals with basic laboratory facilities and essential medicines. In some settings these guidelines can be used in any facilities where sick children are admitted for inpatient care. The Pocket Book is one of a series of documents and tools that support the Integrated Managem.
Infectious diseases are an important cause of malnutrition. Recurrent infections increase the risk of malnutrition while poor nutritional status results in lowered immune status and predisposes to infectious disease thus propagating the vicious cycle of infection and malnutrition. The nutrition-infection-immunity axis is crucial for both developed and developing countries and is now a central feature of many nutrition and infectious disease courses. Bringing together nutrition and immunology, "Nutrition, Immunity and Infections" covers the topic in an accessible format for all studen.
Both nutrition deficiency and overnutrition can have a significant effect on the risk of infection. Nutrition, Immunity, and Infection focuses on the influence of diet on the immune system and how altering one’s diet helps prevent and treat infections and chronic diseases. This book reviews basic immunology and discusses changes in immune function throughout the life course. It features comprehensive chapters on obesity and the role of immune cells in adipose tissue; undernutrition and malnutrition; infant immune maturation; pre- and probiotics; mechanisms of immune regulation by various vitamins and minerals; nutrition and the aging immune system; nutrition interactions with environmental stress; and immunity in the global health arena. Nutrition, Immunity, and Infection describes the various roles of nutrients and other food constituents on immune function, host defense, and resistance to infection. It describes the impact of infection on nutritional status through a translational approach. Chapters bring together molecular, cellular, and experimental studies alongside human trials so that readers can assess both the evidence for the effects of the food component being discussed and the mechanisms underlying those effects. The impact of specific conditions including obesity, anorexia nervosa, and HIV infection is also considered. Chapter authors are experts in nutrition, immunity, and infection from all around the globe, including Europe, Australia, Brazil, India, and the United States. This book is a valuable resource for nutrition scientists, food scientists, dietitians, health practitioners, and students interested in nutrition and immunity.
This manual provides expert practical guidelines for the management of severely malnourished children. Addressed to doctors and other senior health workers, the manual explains exactly what must be done to save lives, achieve successful management and rehabilitation, prevent relapse, and thus give these children the greatest chance of full recovery. Throughout, the importance of treating severe malnutrition as both a medical and a social disorder is repeatedly emphasized. As successful management does not require sophisticated facilities and equipment or highly qualified personnel, the manual also performs a persuasive function, encouraging health professionals to do all they can to save these children and meet their great need for care and affection. Recommended procedures draw on extensive practical experience as well as several recent therapeutic advances. These include improved solutions of oral rehydration salts for the treatment of dehydration, better understanding of the role of micronutrients in dietary management, and growing evidence that physical and psychological stimulation can help prevent long-term consequences of impaired growth and psychological development. Noting that the physiology of malnourished children is seriously abnormal, the manual gives particular attention to aspects of management - whether involving the interpretation of symptoms or the use of specific interventions - that differ considerably from standard procedures for well-nourished children. Details range from the reasons why IV infusion easily causes overhydration and heart failure, through a list of treatments that have no value and should never be used, to the simple reminder that underarm temperature is not a reliable guide to body temperature in a malnourished child during rewarming. Further practical guidance is provided in eight appendices, which use numerous tables, charts, sample recording forms, instructions for preparing feeds, and examples of easily constructed toys to help ensure that management is thorough, safe, and in line with the latest knowledge.
This text provides a review of the roles of specific nutrients in maintaining the immune response and host protection against infection. It also considers the influence of various factors, such as exercise and ageing, on the interaction between nutrition and immune function.
It is a pleasure to write the foreword to Nutrition and Table 1 Nutritional Status and Outcome of Infection Immunology: Principles and Practice. In fact, this book comes at a timely moment, when the impact of nutrition and Definite adverse outcome immunology is being widely felt because of the AIDS epi Measles, diarrhea, tuberculosis demic. This is particularly of note in Africa, where large Probable adverse outcome HIV, malaria, pneumonia sums of money are being spent on nutritional intervention Little or no effect programs in the hopes of improving immune responsive Poliomyelitis, tetanus, viral encephalitis ness. We should not forget, however, early advances in our Note: HIV= human immunodeficiency virus understanding of protein energy malnutrition (PEM). PEM can be used as a model to understand the nutritional basis of immunity, as well as the immunological influences on nutri tional status. Despite advances in agricultural production, tance. However, both in vitro studies and tests in laboratory PEM continues to affect hundreds of millions ofthe world's animals may have little resemblance to what is experienced population. The functional impact of undernutrition varies in humans under field conditions. from mild morbidity to life-threatening infection.
This book provides clear, concise and practical guidelines for treating severely malnourished children successfully, taking into account the limited resources of many hospitals and health units in developing countries, and consistent with other WHO publications. It aims to help improve the quality of inpatient care and so prevent unnecessary deaths, and hospitals which have used these guidelines have reported substantial reductions in mortality rates.
Every aspect of immune function and host defense is dependent upon a proper supply and balance of nutrients. Severe malnutrition can cause significant alteration in immune response, but even subclinical deficits may be associated with an impaired immune response, and an increased risk of infection. Infectious diseases have accounted for more off-duty days during major wars than combat wounds or nonbattle injuries. Combined stressors may reduce the normal ability of soldiers to resist pathogens, increase their susceptibility to biological warfare agents, and reduce the effectiveness of vaccines intended to protect them. There is also a concern with the inappropriate use of dietary supplements. This book, one of a series, examines the impact of various types of stressors and the role of specific dietary nutrients in maintaining immune function of military personnel in the field. It reviews the impact of compromised nutrition status on immune function; the interaction of health, exercise, and stress (both physical and psychological) in immune function; and the role of nutritional supplements and newer biotechnology methods reported to enhance immune function. The first part of the book contains the committee's workshop summary and evaluation of ongoing research by Army scientists on immune status in special forces troops, responses to the Army's questions, conclusions, and recommendations. The rest of the book contains papers contributed by workshop speakers, grouped under such broad topics as an introduction to what is known about immune function, the assessment of immune function, the effect of nutrition, and the relation between the many and varied stresses encountered by military personnel and their effect on health.
Diarrhoea and Malnutrition in Childhood is derived from a conference of pediatric gastroenterologists from around the world, held in London at the Royal Commonwealth Society and St. Bartholomew's Hospital on November 5-7, 1984. They collaborate to create a source that would educate people from developed and developing communities regarding the topic. The book first tackles the connections between diarrhea and malnutrition, and then provides a model that further explains the relationship. The authors suggest that poverty is the main cause of the two abnormal conditions, and they refer to books and studies of the topic by respected figures in the industry. Bacteria that cause the two diseases and the diseases' variations are also covered. Other topics discussed in the book are parasites in the intestine; schemes on how to improve nutrition; importance of breast-feeding; and role that the parts of the human body play during illness. This book will serve as a valuable reference for doctors, researchers, and even casual readers.