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In the last decade, NMR has set the basis for the understanding of the function and disfunction of the human brain. Particularly, Magnetic Resonance Imaging (MRI) has a leading position among the methodologies used for investigation and diagnostic of the Central Nervous System. In the 1990's the objective of finding new investigating means drove scientists towards different approaches, including: 1) Blood Oxygen Level Dependent (BOLD) MRI; 2) Double Magnetic Resonance (DMR); 3) Hyperpolarized Gases. These 3 methods are aimed at detecting brain metabolites with increasing sensitivity and resolution. This Enrico Fermi Course is of interest to researchers who work at the development of these interdisciplinary areas, i.e. physicists, chemists, engineers, but also the biomedical aspects of brain function in connection to the NMR potentialities.
For those wanting to become rapidly acquainted with specific areas of NMR, this title provides unrivalled scope of coverage.
In the last decade, NMR has set the basis for the understanding of the function and disfunction of the human brain. Particularly, Magnetic Resonance Imaging (MRI) has a leading position among the methodologies used for investigation and diagnostic of the Central Nervous System.In the 1990's the objective of finding new investigating means drove scientists towards different approaches, including: 1) Blood Oxygen Level Dependent (BOLD) MRI; 2) Double Magnetic Resonance (DMR); 3) Hyperpolarized Gases. These 3 methods are aimed at detecting brain metabolites with increasing sensitivity and resolution. This Enrico Fermi Course is of interest to researchers who work at the development of these interdisciplinary areas, i.e. physicists, chemists, engineers, but also the biomedical aspects of brain function in connection to the NMR potentialities.
A review of the methods used for analyzing fMRI data, with mathematical outlines of how each method works, and the software available for developing the data. Aimed at graduate students and research investigators.
In the last thirty years, Magnetic Resonance has generated a wide revolution in biomedical research and in medical imaging in general. More recently, the "in vivo" studies of the human brain were extended by new original ways to the dynamic study of function and metabolism of the human brain. The enormous interest in expanding the investigation of the brain is emphasizing the search for new NMR methods capable of extracting information of so-far obscure aspects of the brain function. In fact, many quantitative approaches have been proposed in order to complement the information obtained by functional MRI, and several multimodal and multiparametric approaches have been developed to exploit the information, either functional or structural, made available by the flexible contrast generation typical of MRI, and to combine it with complementary information. The XII workshop of the International School on Magnetic Resonanceand Brain Function, held in Erice between 17 April and 6 May, 2016, was specially devoted to novel approaches aimed at better structural characterization of brain diseases, and at investigating frontiers MRI approaches to better understand the brain function. The papers included in this eBook offer a broad overview of the subjects covered during the Workshop, including applications of multiparametric MRI to neurological diseases, multimodal combination of MRI with electrophysiology, advanced methods for the investigation of brain networks and of brain physiology, and perspectives towards brain state reading.
Functional Magnetic Resonance Imaging (fMRI) has become a standard tool for mapping the working brain's activation patterns, both in health and in disease. It is an interdisciplinary field and crosses the borders of neuroscience, psychology, psychiatry, radiology, mathematics, physics and engineering. Developments in techniques, procedures and our understanding of this field are expanding rapidly. In this second edition of Introduction to Functional Magnetic Resonance Imaging, Richard Buxton – a leading authority on fMRI – provides an invaluable guide to how fMRI works, from introducing the basic ideas and principles to the underlying physics and physiology. He covers the relationship between fMRI and other imaging techniques and includes a guide to the statistical analysis of fMRI data. This book will be useful both to the experienced radiographer, and the clinician or researcher with no previous knowledge of the technology.
In 1971 Dr. Paul C. Lauterbur pioneered spatial information encoding principles that made image formation possible by using magnetic resonance signals. Now Lauterbur, "father of the MRI", and Dr. Zhi-Pei Liang have co-authored the first engineering textbook on magnetic resonance imaging. This long-awaited, definitive text will help undergraduate and graduate students of biomedical engineering, biomedical imaging scientists, radiologists, and electrical engineers gain an in-depth understanding of MRI principles. The authors use a signal processing approach to describe the fundamentals of magnetic resonance imaging. You will find a clear and rigorous discussion of these carefully selected essential topics: Mathematical fundamentals Signal generation and detection principles Signal characteristics Signal localization principles Image reconstruction techniques Image contrast mechanisms Image resolution, noise, and artifacts Fast-scan imaging Constrained reconstruction Complete with a comprehensive set of examples and homework problems, Principles of Magnetic Resonance Imaging is the must-read book to improve your knowledge of this revolutionary technique.
This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completelyimpossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It also focuses on innovative, creative, advanced research that gives full play to imaging technology inthe broad sense, while exploring cross-disciplinary areas in which individual research fields interact and pursuing the development of new techniques where they fuse together. The book is separated into three parts, the first of which addresses the topic of visualizing and controlling molecules for life. Th e second part is devoted to imaging of disease mechanisms, while the final part comprises studies on the application of imaging technologies to diagnosis and therapy. Th e book contains the proceedings of the 12th Uehara International Symposium 2017, “Make Life Visible” sponsored by the Uehara Memorial Foundation and held from June 12 to 14, 2017. It is written by leading scientists in the field and is an open access publication under a CC BY 4.0 license.