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Calibration Handbook of Measuring Instruments is mainly written for operators involved in verifying and calibrating measuring instruments used in Quality Management Systems ISO 9001, Environment Applications ISO 14001, Automotive Industry ISO 16949, and Aviation Industry EN 9100. It is a handy reference and consultation handbook that covers useful topics on assuring and managing industrial process measurement, such as: -The general concepts for managing measurement equipment according to the ISO 10012 concerning the management system of instruments and measurements -An instrument's suitability to perform accurate measurements and control the drift to maintain the quality of the measurement process -The criteria and procedures for accepting, managing, and verifying the calibration of the main industrial measuring instruments -The provisions of law and regulations for production, European marking CE of metrological instruments used in commercial transaction and for their periodic verification Report templates that are useful for recording both the recorded instrument data and the experimental calibration data and evaluating the conformity of the instrument, are available on a CD for practical use. The CD also contains various spreadsheets in Excel, Reports Calibration, which automatically calculate errors and the relative measurement uncertainty for determining a calibrated instrument's compliance.
This book is written for scientists involved in the calibration of viscometers. A detailed description for stepping up procedures to establish the viscosity scale and obtaining sets of master viscometers is given in the book. Uncertainty considerations for standard oils of known viscosity are presented. The modern viscometers based on principles of tuning fork, ultrasonic, PZT, plate waves, Love waves, micro-cantilever and vibration of optical fiber are discussed to inspire the reader to further research and to generate improved versions. The primary standard for viscosity is pure water. Measurements of its viscosity with accuracy/uncertainty achieved are described. The principles of rotational and oscillation viscometers are explained to enhance the knowledge in calibration work. Devices used for specific materials and viscosity in non SI units are discussed with respect to the need to correlate viscosity values obtained by various devices. The description of commercial viscometers meets the needs of the user.
Practical, comprehensive advice on the design, operation, and performance of flowmeters.
Consolidates the information LC-MS bioanalytical scientists need to analyze small molecules and macromolecules The field of bioanalysis has advanced rapidly, propelled by new approaches for developing bioanalytical methods, new liquid chromatographic (LC) techniques, and new mass spectrometric (MS) instruments. Moreover, there are a host of guidelines and regulations designed to ensure the quality of bioanalytical results. Presenting the best practices, experimental protocols, and the latest understanding of regulations, this book offers a comprehensive review of LC-MS bioanalysis of small molecules and macromolecules. It not only addresses the needs of bioanalytical scientists working on routine projects, but also explores advanced and emerging technologies such as high-resolution mass spectrometry and dried blood spot microsampling. Handbook of LC-MS Bioanalysis features contributions from an international team of leading bioanalytical scientists. Their contributions reflect a review of the latest findings, practices, and regulations as well as their own firsthand analytical laboratory experience. The book thoroughly examines: Fundamentals of LC-MS bioanalysis in drug discovery, drug development, and therapeutic drug monitoring The current understanding of regulations governing LC-MS bioanalysis Best practices and detailed technical instructions for LC-MS bioanalysis method development, validation, and stability assessment of analyte(s) of interest Experimental guidelines and protocols for quantitative LC-MS bioanalysis of challenging molecules, including pro-drugs, acyl glucuronides, N-oxides, reactive compounds, and photosensitive and autooxidative compounds With its focus on current bioanalytical practice, Handbook of LC-MS Bioanalysis enables bioanalytical scientists to develop and validate robust LC-MS assay methods, all in compliance with current regulations and standards.
Set includes revised editions of some issues.