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Mathew Woodruff immigrated to Hartford, Connecticut, probably in the 1640's, and settled in Farmington in 1653. He died in 1682.
This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.
James Hosmer, son of Stephen Hosmer, was baptized in 1605 in Hawkhurst, county of Kent, England and later settled in Massachusetts. Descendants lived in Massachusetts, New Hampshire, Connecticut, Vermont, Maine, New York, Michigan, Illinois, and elsewhere.