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A searing account of how vaccine opponents have used the media to spread their message of panic, despite no scientific evidence to support them.
An instant #1 New York Times bestseller! This “timely and compelling” (Kirkus Reviews) middle grade novel about courage, hope, and resilience follows an Asian American boy fighting to keep his family together and stand up to racism during the initial outbreak of the coronavirus. When the coronavirus hits Hong Kong, ten-year-old Knox Wei-Evans’s mom makes the last-minute decision to move him and his siblings back to California, where they think they will be safe. Suddenly, Knox has two days to prepare for an international move—and for leaving his dad, who has to stay for work. At his new school in California, Knox struggles with being the new kid. His classmates think that because he’s from Asia, he must have brought over the virus. At home, Mom just got fired and is panicking over the loss of health insurance, and Dad doesn’t even know when he’ll see them again, since the flights have been cancelled. And everyone struggles with Knox’s blurting-things-out problem. As racism skyrockets during COVID-19, Knox tries to stand up to hate, while finding his place in his new country. Can you belong if you’re feared; can you protect if you’re new? And how do you keep a family together when you’re oceans apart? Sometimes when the world is spinning out of control, the best way to get through it is to embrace our own lovable uniqueness.
In The Case for Vaccine Mandates, Alan Dershowitz—New York Times bestselling author and one of America’s most respected legal scholars—makes an argument, against the backdrop of ideologically driven and politicized objections, for mandating (with medical exceptions) vaccinations as a last resort, if proved necessary to prevent the spread of COVID. Alan Dershowitz has been called “one of the most prominent and consistent defenders of civil liberties in America” by Politico and “the nation’s most peripatetic civil liberties lawyer and one of its most distinguished defenders of individual rights” by Newsweek. He is also a fair-minded and even-handed expert on civil liberties and constitutional rights, and in this book offers his knowledge and insight to help readers understand how mandated vaccination and compulsion to wearing masks should and would be upheld in the courts. The Case for Vaccine Mandates offers a straightforward analytical perspective: If a vaccine significantly reduces the threat of spreading a serious and potentially deadly disease without significant risks to those taking the vaccine, the case for governmental compulsion grows stronger. If a vaccine only reduces the risk and seriousness of COVID to the vaccinated person but does little to prevent the spread or seriousness to others, the case is weaker. Dershowitz addresses these and the issue of masking through a libertarian approach derived from John Stuart Mill, the English philosopher and political economist whose doctrine he summarizes as, “your right to swing your fist ends at the tip of my nose.” Dershowitz further explores the subject of mandates by looking to what he describes as the only Supreme Court decision that is directly on point to this issue; decided in 1905, Jacobson v. Massachusetts involved a Cambridge ordinance mandating vaccination against smallpox and a fine for anyone who refused. In the end, The Case for Vaccine Mandates represents an icon in American law and due process reckoning with what unfortunately has become a reflection of our dangerously divisive age, where even a pandemic and the responses to it, divide us along partisan and ideological lines. It is essential reading for anyone interested in a non-partisan, civil liberties, and constitutional analysis.
Three months have passed since Shea Kelly and the rest of Boss's crew eliminated Danny Rose from the Non-Compliance Sector, but their troubles are far from over. A new, more dangerous opponent has emerged, causing those once considered enemies to strike a tenuous truce. Secrets about the vaccine, the chip, and the past threaten Shea's budding romance, not to mention the very existence of the crew.
In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.
No doubt 2020 was a challenging year for some, and tough for others due to COVID-19 pandemic. The early announcement of the vaccine at the beginning of 2021 gave several communities the hope to terminate this pandemic and made them believe they could shortly go back to normal life. Meanwhile, others were doubtful concerning the efficacy of the vaccine itself and advocated against it. In this book, we are representing the two sides – those who are for and those who are against the idea of vaccination. We do so by uncovering the historical fights and presenting various factors (religious, political, personal and industrial) concerning the vaccines and vaccination and by showing how different the perspectives of various people can be. We believe this book will build a bridge of trust and create an open dialogue for both sides. Whether you are off medical background or not, this book will be a valuable source of information. We did our best to clarify the medical terms and conditions and to explain in simple words the mechanisms that might seem difficult at first. Hopefully, this will make the time spent reading this book both informative and useful.
This collection seeks to elucidate the practical methods necessary for successful adjuvant development, with a particular focus on the synthesis, formulation, manufacturing, and characterization aspects involved. Beginning with an overview and a case study, the book then delves into in silico design, chemical synthesis, biosynthesis, and/or purification from natural raw materials of specific adjuvant molecules, adjuvant formulation approaches, the analytical characterization of adjuvant formulations and adjuvant-containing vaccines, as well as the biological characterization of vaccine adjuvant activity, including in vitro and in vivo approaches, to measure innate and adaptive immune responses. Written in the highly successful Methods in Molecular Biology format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and authoritative, Vaccine Adjuvants: Methods and Protocols aims to facilitate vaccine adjuvant product development efforts, making them more accessible, manufacturable, and better characterized.
The inside story of an unprecedented feat of science and business. At the start of 2020, Moderna was a biotech unicorn with dim prospects. Yes, there was the promise of its disruptive innovation that could transform medicine by using something called messenger RNA, one of the body's building blocks of life, to combat disease. But its stock was under water. There were reports of a toxic work culture. And despite ten years of work, the company was still years away from delivering its first product. Investors were getting antsy, or worse, skeptical. Then the pandemic hit, and Moderna, at first reluctantly, became a central player in a global drama—a David to Big Pharma's Goliaths—turning its technology toward breaking the global grip of the terrible disease. By year's end, with the virus raging, Moderna delivered one of the world's first Covid-19 vaccines, with a stunningly high rate of protection. The achievement gave the world a way out of a crippling pandemic while validating Moderna's technology, transforming the company into a global industry power. Biotech, and the venture capital community that fuels it, will never be the same. Wall Street Journal reporter Peter Loftus, veteran reporter covering the pharmaceutical and biotech industries and part of a Pulitzer Prize–finalist team, brings the inside story of Moderna, from its humble start at a casual lunch through its heady startup days, into the heart of the pandemic and beyond. With deep access to all of the major players, Loftus weaves a tale of science and business that brings to life Moderna's monumental feat of creating a vaccine that beat back a deadly virus and changed the business of medicine forever. The Messenger spans a decade and is full of heroic efforts by ordinary people, lucky breaks, and life-and-death decisions. It's the story of a revolutionary idea, the evolution of a cutting-edge American industry, and one of the great achievements of this century.