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From the award-winning author of Finding Mighty, a moving middle-grade novel about finding your place by following your heart Karthik Raghavan is good at remembering things. Like his bike routes. Or all the reasons he likes Juhi Shah—even if she doesn’t even know he exists. It doesn't help that she seems to have a crush on his arch nemesis, Jacob Donnell, whose only job is to humiliate Karthik (and get his name wrong). Then Karthik's luck changes when he secretly agrees to be in a play about the famous musician, Leonard Bernstein. But he can't tell his parents. The family store is in jeopardy, and they need him delivering groceries on his bike to help save it. His mom is also worried about the Financial Crisis, and she's convinced that studying hard and staying focused is the only way to succeed. But Karthik is having fun being Lenny. Besides, what if acting is Karthik’s special talent? And what if acting is the one way to catch Juhi Shah’s attention? With all the pressure from his family to succeed, will Karthik be able to really imagine and hope when he’s not sure what will happen next?
Along the train lines north of New York City, twelve-year-old neighbors Myla and Peter search for the link between Myla’s necklace and the disappearance of Peter’s brother, Randall. Thrown into a world of parkour, graffiti, and diamond-smuggling, Myla and Peter encounter a band of thugs who are after the same thing as Randall. Can Myla and Peter find Randall before it’s too late, and their shared family secrets threaten to destroy them all? Drawing on urban art forms and local history, Finding Mighty is a mystery that explores the nature of art and the unbreakable bonds of family.
Are you under pressure to deliver? Is your life made tough by shortened schedules, tight budgets, skills gap, incomplete scope, and demanding stakeholders? Do you need help in the form of proven practical tips and techniques to help you confidently deliver project success? This book will certainly help you. What’s inside? • Superb set of 52 proven project success keys • Unbeatable breadth of insights: 108 experts, 2000+ projects, 119 countries • Comprehensive solutions to the top 20 global project failure factors • Coverage of waterfall, hybrid and agile methodologies in 54 industries • Extensive discussions on soft skills, leadership and communication • Situation, impact, and resolution presentation technique • Storytelling approach for easy understanding Read on to get your project off to a flying start and deliver in style!
The SourceForge open source lightweight Wicket project is a Java web application framework that takes simplicity, separation of concerns and ease of development to a new level. This book takes a no-nonsense approach, jumping directly to the practical aspects of Wicket. Chapters include Developing Wicket Forms; Validation with Wicket; Developing a Simple Application; Providing a Common Layout; Spring Integration; Wicket Localization; Wicket and Ajax; Custom Components and Wicket Extensions, and Unit Testing. Pro Wicket gets you quickly up and running with the framework and the attractively simple ‘wicket-way’ of addressing web development requirements.
Find sustainable inner peace and happiness with The Happiness Model.
An enormously satisfying, exciting and enriching book, Vikram Chandra's novel draws the reader deep into the lives of detective Sartaj Singh and Ganesh Gaitonde, the most wanted gangster in India. Sartaj, the only Sikh inspector in the whole of Mumbai, is used to being identified by his turban, beard and the sharp cut of his trousers. But 'the silky Sikh' is now past forty, his marriage is over and his career prospects are on the slide. When Sartaj gets an anonymous tip off as to the secret hideout of the legendary boss of the G-company, he's determined that he'll be the one to collect the prize. This is a sprawling, epic novel of friendships and betrayals, of terrible violence, of an astonishing modern city and its underworld. Drawing on the best of Victorian fiction, mystery novels, Bollywood movies and Vikram Chandra's years of first hand research on the streets of Mumbai, this novel reads like a potboiling page-turner but resonates with the intelligence and emotional depth of the best of literature.
A Wharton professor and tech entrepreneur examines how algorithms and artificial intelligence are starting to run every aspect of our lives, and how we can shape the way they impact us Through the technology embedded in almost every major tech platform and every web-enabled device, algorithms and the artificial intelligence that underlies them make a staggering number of everyday decisions for us, from what products we buy, to where we decide to eat, to how we consume our news, to whom we date, and how we find a job. We've even delegated life-and-death decisions to algorithms--decisions once made by doctors, pilots, and judges. In his new book, Kartik Hosanagar surveys the brave new world of algorithmic decision-making and reveals the potentially dangerous biases they can give rise to as they increasingly run our lives. He makes the compelling case that we need to arm ourselves with a better, deeper, more nuanced understanding of the phenomenon of algorithmic thinking. And he gives us a route in, pointing out that algorithms often think a lot like their creators--that is, like you and me. Hosanagar draws on his experiences designing algorithms professionally--as well as on history, computer science, and psychology--to explore how algorithms work and why they occasionally go rogue, what drives our trust in them, and the many ramifications of algorithmic decision-making. He examines episodes like Microsoft's chatbot Tay, which was designed to converse on social media like a teenage girl, but instead turned sexist and racist; the fatal accidents of self-driving cars; and even our own common, and often frustrating, experiences on services like Netflix and Amazon. A Human's Guide to Machine Intelligence is an entertaining and provocative look at one of the most important developments of our time and a practical user's guide to this first wave of practical artificial intelligence.
This book delivers a comprehensive and insightful account of applying mathematical modelling approaches to very large biological systems and networks—a fundamental aspect of computational systems biology. The book covers key modelling paradigms in detail, while at the same time retaining a simplicity that will appeal to those from less quantitative fields. Key Features: A hands-on approach to modelling Covers a broad spectrum of modelling, from static networks to dynamic models and constraint-based models Thoughtful exercises to test and enable understanding of concepts State-of-the-art chapters on exciting new developments, like community modelling and biological circuit design Emphasis on coding and software tools for systems biology Companion website featuring lecture videos, figure slides, codes, supplementary exercises, further reading, and appendices: https://ramanlab.github.io/SysBioBook/ An Introduction to Computational Systems Biology: Systems-Level Modelling of Cellular Networks is highly multi-disciplinary and will appeal to biologists, engineers, computer scientists, mathematicians and others.
Animals make for terrible technology. The technological use of animals--making food, drugs, clothing, and cosmetics out of animal material--will cease. A cow takes over one year to grow, "wastes" over ninety percent of what it's fed, and cannot be innovated much further. After Meat explains the fundamental limits of animal technology in terms of physics and biology. Replacement technology such as microbial fermentation will surpass those limits. Eventually, we'll have food that is better in every way--in terms of taste, cost, nutrition, resource consumption, and ethics--because we won't use animals to produce it. Along the way, After Meat leads us through a veritable forest of adjacent topics. We wade into evolution and reductivism, broach consciousness and the Multiverse, dive into economics and policy, bounce from weather prediction to the problem of hunger to the morality of eating plants. In sum, we ineluctably conclude that our future has little room for animal technology, and that future will be better for it.
Development of strategies to assist the movement of poorly permeable molecules across biological barriers has long been the goal of drug delivery science. In the last three decades, there has been an exponential increase in advanced drug delivery systems that aim to address this issue. However, most proprietary delivery technologies that have progressed to clinical development are based on permeation enhancers (PEs) that have a history of safe use in man. This Special Issue entitled “Transmucosal Absorption Enhancers in the Drug Delivery Field” aims to present the current state-of-the-art in the application of PEs to improve drug absorption. Emphasis is placed on identification of novel permeation enhancers, mechanisms of barrier alteration, physicochemical properties of PEs that contribute to optimal enhancement action, new delivery models to assess PEs, studies assessing safety of PEs, approaches to assist translation of PEs into effective oral, nasal, ocular and vaginal dosage forms and combining PEs with other delivery strategies.