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This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
In the corridors of the Vatican on the eve of World War II, American Catholic priest Joseph Patrick Hurley found himself in the midst of secret diplomatic dealings and intense debate. Hurley’s deeply felt American patriotism and fixed ideas about confronting Nazism directly led to a mighty clash with Pope Pius XII. It was 1939, the earliest days of Pius’s papacy, and controversy within the Vatican over policy toward Nazi Germany was already heated. This groundbreaking book is both a biography of Joseph Hurley, the first American to achieve the rank of nuncio, or Vatican ambassador, and an insider’s view of the alleged silence of the pope on the Holocaust and Nazism. Drawing on Hurley’s unpublished archives, the book documents critical debates in Pope Pius’s Vatican, secret U.S.-Vatican dealings, the influence of Detroit’s flamboyant anti-Semitic priest Charles E. Coughlin, and the controversial case of Croatia’s Cardinal Stepinac. The book also sheds light on the powerful connections between religion and politics in the twentieth century.
From the preface: "The 1966 'Human Factors' edition focused on the contemporary threat of Maoist insurgencies, particularly in Southeast Asia, and also drew extensively on World War II resistance movements in Europe. Much of this information is still relevant and has been retained and integrated. In the post-Cold War world, the most important insurgencies tend to be ethnic and religious. Long-simmering conflicts, sometimes with roots in colonial policies, have become prominent; examples include the Liberation Tigers of Tamil Eelam (LTTE) in Sri Lanka, Euskadi Ta Askatasuna (Basque Homeland and Freedom or ETA) in Spain, the Hutu-Tutsi genocides, the Ushtia �lirimtare e Kosov�s (Kosovo Liberation Army, or KLA), and the Provisional Irish Republican Army (PIRA). Battle lines in these conflicts are often drawn along ethnic lines, even when land or politics are the immediate issues in contention. The other important new category is extremist religious movements, most prominently Islamic groups, including regional insurgent movements like Hizbollah and Harakat al-Muqawamah al'Isla�miyyah (Islamic Resistance Movement, or HAMAS) and global movements like Al Qaeda. These present a different profile of ideology, organizational forms, and psychology than either Cold War Maoists or post-colonial ethnic insurgencies (although the Palestinian cause could be considered a post-colonial issue). Globalization has also changed underground operations in numerous ways. Insurgencies, enabled by low-cost transportation, Internet based communications, and other information technologies, can more easily recruit, communicate, and operate across borders. It is correspondingly much more difficult to contain an insurgency in a region. Global media has led to development of new tactics, in particular new types of terrorism, designed to capture worldwide attention. Compared with what was available in the 1960s, there are orders of magnitude more academic research available relevant to this study's topics. We were able to draw on more recent work in psychology, political science, economics, sociology, organizational studies, and communications studies. Readers of this edition will, over the course of eleven chapters, get a wide exposure to basic concepts from a number of disciplines".
In his eagerly-awaited second edition of American Foreign Policy and Political Ambition, James Ray revisits his deceptively simple premise that the highest priority of leaders is to stay in power. Looking at how political ambition and domestic pressures impact foreign policymaking is the key to understanding how and why foreign policy decisions are made. The text begins by using this analytic approach to look at the history of foreign policymaking and then examines how various parties inside and outside government influence decision making. In a unique third section, the book takes a regional approach, not only covering trends other books tend to miss, but giving students the opportunity to think comprehensively about how issues intersect around the globe—from human security and democratization, to globalization and pollution. Guided by input from adopters and reviewers, Ray has thoroughly re-organized the book and streamlined some coverage to better consolidate the historical, institutional, regional, and topical chapters and focus the thematic lens of the book. Ray has also brought the book fully up-to-date, addressing the latest events in American foreign policy, including the wars in Afghanistan and Iraq, the killing of Bin Laden, the WikiLeaks scandal and its aftermath, the impact of social media on foreign policy and world affairs, nuclear proliferation, developments in U.S.-Russian relations, climate change, and more.