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Original publication and copyright date: 2009.
Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.
Updated edition of the beloved classic by the Queen of Regency romance herself, Georgette Heyer, featuring a new Foreword by New York Times bestselling author Eloisa James. Arabella's one little while lie has spread through the ton like wildfire... Arabella Tallant, modest daughter of a country clergyman, is on her way to her first London Season when her carriage breaks down outside the estate of the wealthy and bored Mr. Robert Beaumaris. Beau assumes she's simply another young lady throwing herself in his path, which goads the impetuous Arabella into pretending she's an heiress. Much to Arabella's dismay, rather than being brutally set-down, as she intended, Beaumaris is deeply amused. He counters by launching her into high society, which Arabella would enjoy very much if it wasn't for the fortune hunters. Arabella's unpredictable and innocent ways force Beaumaris to start helping others, including a stray dog, an unfortunate urchin, and eventually Arabella's reckless young brother. Along the way, Arabella and Beaumaris become more and more intrigued with each other—which neither will admit, of course, until under extreme duress. "Absolutely delicious tales of Regency heroes... Utter, immersive escapism."—SOPHIE KINSELLA "No one has ever matched Georgette Heyer for charm and wit." —LISA KLEYPAS "Utterly timeless charm... The dialogue sparkles with wit." —NORA ROBERTS, #1 New York Times bestselling author "Romance, adventure, side-splitting humor—no one writes like Georgette Heyer!" —LAUREN WILLIG, New York Times bestselling author
James L. Machor offers a sweeping exploration of how American fiction was received in both public and private spheres in the United States before the Civil War. Machor takes four antebellum authors—Edgar Allan Poe, Herman Melville, Catharine Sedgwick, and Caroline Chesebro'—and analyzes how their works were published, received, and interpreted. Drawing on discussions found in book reviews and in private letters and diaries, Machor examines how middle-class readers of the time engaged with contemporary fiction and how fiction reading evolved as an interpretative practice in nineteenth-century America. Through careful analysis, Machor illuminates how the reading practices of nineteenth-century Americans shaped not only the experiences of these writers at the time but also the way the writers were received in the twentieth century. What Machor reveals is that these authors were received in ways strikingly different from how they are currently read, thereby shedding significant light on their present status in the literary canon in comparison to their critical and popular positions in their own time. Machor deftly combines response and reception criticism and theory with work in the history of reading to engage with groundbreaking scholarship in historical hermeneutics. In so doing, Machor takes us ever closer to understanding the particular and varying reading strategies of historical audiences and how they impacted authors’ conceptions of their own readership.
One of the most beloved novels of all time, Colleen McCullough's magnificent saga of dreams, struggles, dark passions, and forbidden love in the Australian outback has enthralled readers the world over. The Thorn Birds is a chronicle of three generations of Clearys—an indomitable clan of ranchers carving lives from a beautiful, hard land while contending with the bitterness, frailty, and secrets that penetrate their family. It is a poignant love story, a powerful epic of struggle and sacrifice, a celebration of individuality and spirit. Most of all, it is the story of the Clearys' only daughter, Meggie, and the haunted priest, Father Ralph de Bricassart—and the intense joining of two hearts and souls over a lifetime, a relationship that dangerously oversteps sacred boundaries of ethics and dogma.
The invention of mass marketing led to cigarettes being emblazoned in advertising and film, deeply tied to modern notions of glamour and sex appeal. It is hard to find a photo of Humphrey Bogart or Lauren Bacall without a cigarette. No product has been so heavily promoted or has become so deeply entrenched in American consciousness. And no product has received such sustained scientific scrutiny. The development of new medical knowledge demonstrating the dire harms of smoking ultimately shaped the evolution of evidence-based medicine. In response, the tobacco industry engineered a campaign of scientific disinformation seeking to delay, disrupt, and suppress these studies. Using a massive archive of previously secret documents, historian Allan Brandt shows how the industry pioneered these campaigns, particularly using special interest lobbying and largesse to elude regulation. But even as the cultural dominance of the cigarette has waned and consumption has fallen dramatically in the U.S., Big Tobacco remains securely positioned to expand into new global markets. The implications for the future are vast: 100 million people died of smoking-related diseases in the 20th century; in the next 100 years, we expect 1 billion deaths worldwide.
Incompetent! She couldn’t cook, clean or operate the dishwasher. But Steven Koleski had to admit the mysterious woman did have a way with his newfound family...and his lonely heart. It was the opportunity of a lifetime for Princess Sophie of Carpathia: two weeks of living like a regular person. On top of that, caring for children was her passion. But with five of them tugging on her heartstrings and their sexy guardian bestowing fiery kisses on her, how could she ever return to life as a princess when her fairy-tale ending was right here...right now?