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As seen in the new movie The Post, directed by Steven Spielberg and starring Meryl Streep, here is the captivating, inside story of the woman who piloted the Washington Post during one of the most turbulent periods in the history of American media. In this bestselling and widely acclaimed memoir, Katharine Graham, the woman who piloted the Washington Post through the scandals of the Pentagon Papers and Watergate, tells her story - one that is extraordinary both for the events it encompasses and for the courage, candour and dignity of its telling. Here is the awkward child who grew up amid material wealth and emotional isolation; the young bride who watched her brilliant, charismatic husband - a confidant to John F. Kennedy and Lyndon Johnson - plunge into the mental illness that would culminate in his suicide. And here is the widow who shook off her grief and insecurity to take on a president and a pressman's union as she entered the profane boys' club of the newspaper business. As timely now as ever, Personal History is an exemplary record of our history and of the woman who played such a shaping role within them, discovering her own strength and sense of self as she confronted - and mastered - the personal and professional crises of her fascinating life.
Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.