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One of the great medical controversies of the Enlightenment was the European debate on motion, sensation, and animal experimentation provoked by Albrecht von Haller’s treatise on irritability and sensibility (1752). Irritating Experiments is the first full-length study to explore the theoretical background and the experimental process that led to Haller's description and separation of two fundamental bodily qualities: irritability, or the capacity of muscles to contract upon stimulation, and sensibility, or the capacity of the nervous system to transmit impressions that are felt as touch or pain in humans, or produce signs of pain in animals. This new concept presented a serious challenge to the reigning medical systems. Haller’s animal experiments were repeated all over Europe, on a scale never seen before. The results, however, were contradictory. Haller's concept was largely rejected, and animal experimentation could not be established as a major research method in physiology. Focussing on procedural aspects of experimentation, the interaction between experiment and theory, the status of surgery, the use of medical and pathological models, and the culture of criticism, Irritating Experiments tries to explain why.
Includes the transactions of the American Surgical Association, New York Surgical Society, Philadelphia Academy of Surgery, Southern Surgical Association, Central Surgical Association, and at various times, of other similar organizations.
In Scholars in Action, an international group of 40 authors open up new perspectives on the eighteenth-century culture of knowledge, with a particular focus on scholars and their various practices.
Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.