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ull recognition of the important role that hormones play in the growth, F differentiation, and function of insects was preceded by rather advanced information about identity and action of mammalian hormones. However, extirpation and transplantation of endocrine glands in insects and segmental ligation of larvae gradually yielded knowledge about the location of endo crine cells in insects and led to labeling their hormonal product with appropriate names. The development of relatively sensitive assays permitted the separation of active extracts of the hormones associated with meta morphosis and quickened the pace of discovery. Finally, identification of structural formulae of natural hormones now has provided the means for detailed study of biochemical events with which they are associated. In the meantime, better interpretation of the mechanism for morphologic and functional effects of hormones in vertebrates has come about through knowledge of binding of hormones in target tissues, feed-back, and other mechanisms. There has been a prodigious increase in information recently, not only about the structure of molting and juvenile hormones, but also about their molecular action, as well as recognition of problems still posed by their of origin, and relation to genic derepression. biosynthesis, interactions, sites Discovery and study of phytohormones and analogs has added interest and amplified techniques for investigation.
First published in 1986. Taken from the Tin and Cell Malignancy Symposium, this volume will help others to appreciate the interdisciplinary nature of this field.
ull recognition of the important role that hormones play in the growth, F differentiation, and function of insects was preceded by rather advanced information about identity and action of mammalian hormones. However, extirpation and transplantation of endocrine glands in insects and segmental ligation of larvae gradually yielded knowledge about the location of endo crine cells in insects and led to labeling their hormonal product with appropriate names. The development of relatively sensitive assays permitted the separation of active extracts of the hormones associated with meta morphosis and quickened the pace of discovery. Finally, identification of structural formulae of natural hormones now has provided the means for detailed study of biochemical events with which they are associated. In the meantime, better interpretation of the mechanism for morphologic and functional effects of hormones in vertebrates has come about through knowledge of binding of hormones in target tissues, feed-back, and other mechanisms. There has been a prodigious increase in information recently, not only about the structure of molting and juvenile hormones, but also about their molecular action, as well as recognition of problems still posed by their of origin, and relation to genic derepression. biosynthesis, interactions, sites Discovery and study of phytohormones and analogs has added interest and amplified techniques for investigation.
First published in 1989: This text was written to provide a relatively broad comprehensive study of the thymus in health and disease, including relationships to the endocrine system, immue system, and again.
Physiology of Ticks focuses on the unique (and probably the most vulnerable) features of tick physiology and the physiological aspects of tick interactions with their hosts. The mechanisms used by non-feeding ticks to maintain their water balance are examined, along with the salivary mechanisms used by feeding ixodid ticks for excreting the enormous excess volumes of water and salts taken in during blood sucking. This book is comprised of 13 chapters and begins with a description of the morphology, deposition, and components of the tick cuticle. The discussion then turns to humidity relationships and water balance of ticks, as well as the sensory basis of tick feeding behavior and the immunological basis of host resistance to ticks. Subsequent chapters explore blood digestion in ticks; tick reproduction, with emphasis on sperm development, cytogenetics, oogenesis, and oviposition; effects of insect hormones and their mimics on tick development and reproduction; and the mechanisms of tick pheromones. The final chapter deals with diapause and biological rhythms in ticks. This monograph will be of value to entomologists, physiologists, biologists, and practitioners of tropical science.
Endocrinology II concerns the actions of hormones in insects, complementing Volume 7 which is concerned with the production and chemistry of insect hormones. While the preceding volume is directed mainly towards the insect endocrinologist, this volume has much of intrinsic interest to the general physiologist. It deals with the regulation of metabolism, reproduction, cuticle properties, and certain aspects of behaviour from a systems point of view and amply documents how hormones have provided basic insights into the functioning of such systems. Interference in endocrine regulation could provide future systems for insect control and this volume will provide the foundation on which the future formulation of these strategies is based. More information on diverse aspects of insect hormone action is brought together here than in any previous single work and this volume will therefore be a valuable reference source for many years to come.
Ecdysone is the steroidal prohormone of the major insect moulting hormone 20-hydroxyecdysone. It groups with its homologues the steroidal molting hormones in arthropods, but they also occur in other phyla where they can play different roles. Besides ecdysteroids appear in many plants mostly as protection agents (toxins or antifeedants) against herbivorous insects. The important developments and achievements in modern ecdysone science since the first edition in 1989 by J. Koolman have led to this new revised, expanded and retitled reference work. New chapters in this edition include RNA interference, the ecdysone receptor crystal structures and structure activity relationships, etc. Each article may also be read independently, as a review of that particular subject. Complete up-to-date coverage of many important topics - the book is divisible into five conceptual areas: (1) Distribution and diversity of ecdysteroids in the two kingdoms is still basis, (2) In the post-genomic era, ecdysteroid genetic hierarchies in insect growth and reproduction, (3) Role of cross talk of genes and growth factors in ecdysteroid titers and signaling, (4) Ecdysteroids function through nuclear and membrane receptors, and (5) Ecdysteroids in modern agriculture, medicine, doping and ecotoxicology. Each of the 23 chapters is written by scientists active in the reviewed research area and a truly distinguished international team of contributors has been chosen. Ecdysone, Structures and Functions will be of immense use and contains essential information for scientists, students, and professionals alike in entomology, endocrinology, physiology, chemistry, and agricultural, plant, biomedicine and environmental sciences.
The juvenile hormones of insects are unique molecules in terms of their chemical nature (methyl esters of sesquiterpene epoxides) and action (both as modulators of morphogenesis during the larval life of insects and as a gonadotropic agent in many female adults). Although a symposium dedicated to the chemistry, metabolism and effects of juvenile hormone at a number of levels would be merited on the basis of its interest to the chemist, physiologist, endo crinologist, developmental biologist and entomologist, the juvenile hormones are special in the sense that juvenile hormone mimics (juvenoids, insect growth regulators, analogs) are currently being utilized to control various insec. t pests. Indeed, a number of commercial firms are currently developing new compounds with juven ile hormone activity that might possess a narrow spectrum of acti vity and which would be relatively biodegradable. Thus, a symposium on the juvenile hormones is also merited on a practical basis since juvenoids are already becoming constituents of our environment and it is apparent that in order to design effective mimics of the natural juvenile hormones, o~e should understand the means by which juvenile hormone elicits its effects. As will become evident to the reader, the great majority of data presented at this symposium have not been published previously and the symposium itself was organized along natural divisions dealing with the chemistry, metaoolism and multi-level modes of action of the juvenile hormones. Special lectures were presented by Professors C. M. Williams, B. W. O'Malley and W. S.
Ecdysone: From Metabolism to Regulation of Gene Expression presents papers from the Seventh Ecdysone Workshop held in Edinburgh, UK from March 31 to April 3, 1985. The book discusses the biosynthesis, distribution, and metabolism of ecdysteroids; the ecdysteroid action and hormone receptors; and the ecdysone inducible genes. The text also describes hormones and oogenesis; the interactions with other hormones, studies on other hormones, and practical applications of ecdysteroid studies.