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This updated edition of an Artech House classic introduces readers to the importance of engineering in medicine. Bioelectrical phenomena, principles of mass and momentum transport to the analysis of physiological systems, the importance of mechanical analysis in biological tissues/ organs and biomaterial selection are discussed in detail. Readers learn about the concepts of using living cells in various therapeutics and diagnostics, compartmental modeling, and biomedical instrumentation. The book explores fluid mechanics, strength of materials, statics and dynamics, basic thermodynamics, electrical circuits, and material science. A significant number of numerical problems have been generated using data from recent literature and are given as examples as well as exercise problems. These problems provide an opportunity for comprehensive understanding of the basic concepts, cutting edge technologies and emerging challenges. Describing the role of engineering in medicine today, this comprehensive volume covers a wide range of the most important topics in this burgeoning field. Moreover, you find a thorough treatment of the concept of using living cells in various therapeutics and diagnostics. Structured as a complete text for students with some engineering background, the book also makes a valuable reference for professionals new to the bioengineering field. This authoritative textbook features numerous exercises and problems in each chapter to help ensure a solid understanding of the material.
A two-in-one text providing teaching lab students with an overview of immunology as well as a lab manual complete with current standard exercises. Section I of this book provides an overview of the immune system and immunity, and includes review questions, problem sets, case studies, inquiry-based questions, and more to provide students with a strong foundation in the field. Section II consists of twenty-two lab exercises focused on key concepts in immunology, such as antibody production, cell separation, cell function, immunoassays, Th1/Th2 cytokine detection, cell and tissue culture methods, and cell and molecular biology techniques. Appendices include safety information, suggested links and readings, and standard discipline processes, protocols, and instructions.
Knowledge gained within the individual areas of law and ethics, pharmaceutics, pharmacology and pathology are tested by each example, bringing together all areas taught on the degree course. Each chapter contains five case studies, starting with uncomplicated cases and increasing in complexity as they expand.
This volume presents methods used for the analysis of glycoproteins at different levels—intact, subunit, glycopeptide, and monosaccharide--, and discusses and solves most analytical challenges that a scientist working on glycoproteins may come across. The chapters in this book cover topics such as the role of glycosylation on the properties of therapeutic glycoproteins; different analytical methods to characterize glycosylation, from the intact proteins to the glycan level, for both N-linked and O-linked glycoproteins; mass spectrometry imaging methodology for glycosylation analysis in tissues; approaches to characterizing glycosylation on cultured cells; and the use of cloud computing to deploy mass spectrometry data analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Mass Spectrometry of Glycoproteins: Methods and Protocols is a valuable resource for scientists interested in learning more about this developing field.
Synthesis of Organotransition Metals.- Metallocarboranes: Past, Present, and Future.- Novel Rhodium and Palladium Complexes with Benzoyl and Thiobenzoyl Isocyanates as Ligands.- Polycyanovinyl Transition Metal Derivatives.- A New Preparation of Organocopper(I)-Isonitrile Complexes and Their Reactions.- An Unusual Behavior of?-Vinyl Alcohol Complexes of Transition Metals.- The Mode of Formation of Transition Metal to Carbon Bonds by Oxidative Addition.- Organoactinides: Coordination Patterns and Chemical Reactivity.- Recent Developments in Chemistry of Organolanthanides and Organoactinides.- C.
also occurs. New outbreaks of yellow fever have occurred in Colombia and Trinidad and new outbreaks of rift valley fever have occurred in Egypt. Chapter 6, Arenaviruses: The biochemical and physical properties have now been clar ified, and they show a remarkable uniformity in the various viruses constituting the group. The possibility that prenatal infection with LCM may result in hydrocephalus and chorioretinitis has been raised. Serologic surveys have suggested the existence of Lassa virus infection in Guinea, Central African Empire, Mali, Senegal, Cameroon, and Benin, in addition to earlier identification in Nigeria, Liberia, and Sierra Leone. Chapter 7, Coronaviruses: New studies have confirmed the important role of these viruses in common respiratory illnesses of children and adults. The viruses are now known to contain a single positive strand of RNA. About 50% of corona virus infections result in clinical illness. About 5% of common colds are caused by strain DC 43 in winter. Chapter 8, Cytomegalovirus: Sections on pathogenesis of CMV in relation to organ transplantation and mononucleosis, as well as sections on the risk and features of con genital infection and disease, have been expanded. There are encouraging preliminary results with a live CMV vaccine, but the questions of viral persistence and oncogenicity require further evaluation.
A volume in the Contemporary Perspectives In Rehabilitation Series, edited by Steven L. Wolf, PhD, PT, FAPTA. Rely on the completely revised and thoroughly updated 4th Edition of this innovative textbook to insure that your students will be able to master this complex content with ease. Organized by body system, each chapter begins with a description of the drug...followed by an explanation of the conditions it treats...and ends with a discussion of how the drug affects physical therapy and how physical therapy may impact drug effectiveness. Dr. Ciccone's easy-to-understand writing style demystifies the science and practice of pharmacology.