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Proton Therapy Physics goes beyond current books on proton therapy to provide an in-depth overview of the physics aspects of this radiation therapy modality, eliminating the need to dig through information scattered in the medical physics literature. After tracing the history of proton therapy, the book summarizes the atomic and nuclear physics background necessary for understanding proton interactions with tissue. It describes the physics of proton accelerators, the parameters of clinical proton beams, and the mechanisms to generate a conformal dose distribution in a patient. The text then covers detector systems and measuring techniques for reference dosimetry, outlines basic quality assurance and commissioning guidelines, and gives examples of Monte Carlo simulations in proton therapy. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. It also examines computerized treatment plan optimization, methods for in vivo dose or beam range verification, the safety of patients and operating personnel, and the biological implications of using protons from a physics perspective. The final chapter illustrates the use of risk models for common tissue complications in treatment optimization. Along with exploring quality assurance issues and biological considerations, this practical guide collects the latest clinical studies on the use of protons in treatment planning and radiation monitoring. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, the book helps readers understand the uncertainties and limitations of precisely shaped dose distribution.
Intermediate-Energy Nuclear Physics is devoted to discussing the interaction between hadrons with nuclei, which leads to the emission of particles during an intranuclear cascade and subsequent decay of a highly excited residual nucleus. Experimental data and the methods and results of the calculation of probabilities of various processes initiated by intermediate-energy hadrons in nuclei are set forth and discussed. The potential for obtaining information on the structure and properties of nuclei by comparing experimental data with theoretical results is analyzed. New issues, such as analytic methods for the solution of kinetic equations describing the cascade, nuclear absorption of hadrons from bound states of hadronic atoms, interaction of antinucleons with nuclei, multifragmentation of highly excited residual nuclei, and polarization phenomena, are discussed in detail. The book also demonstrates hadron-nucleus interactions that bridge the gap between low-energy and heavy ions physics. It is an interesting reference for nuclear physicists and other researchers interested in the analysis of problems associated with the evolution of the early (hot) universe, neutron stars and supernovas, after-burning of radioactive waste in nuclear energy installations, and electronuclear energy breeding.
Dramatic progress has been made in all branches of physics since the National Research Council's 1986 decadal survey of the field. The Physics in a New Era series explores these advances and looks ahead to future goals. The series includes assessments of the major subfields and reports on several smaller subfields, and preparation has begun on an overview volume on the unity of physics, its relationships to other fields, and its contributions to national needs. Nuclear Physics is the latest volume of the series. The book describes current activity in understanding nuclear structure and symmetries, the behavior of matter at extreme densities, the role of nuclear physics in astrophysics and cosmology, and the instrumentation and facilities used by the field. It makes recommendations on the resources needed for experimental and theoretical advances in the coming decade.