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The purpose of this book is to examine the etiology of cancer in large human populations using mathematical models developed from an inter-disciplinary perspective of the population epidemiological, biodemographic, genetic and physiological basis of the mechanisms of cancer initiation and progression. In addition an investigation of how the basic mechanism of tumor initiation relates to general processes of senescence and to other major chronic diseases (e.g., heart disease and stroke) will be conducted.
The first look at the prehistory of Texas by 16 professional archaeologist.
Debitage, the by-product flakes and chips from stone tool production, is the most abundant artifact type found on prehistoric sites. Archaeologists now recognise its potential in providing information about the kinds of tools produced, the characteristics of the technology that produced them, human mobility patterns and even site function, applying scientific analyses to its study. This volume brings together some of the most recent research on debitage analysis and intepretation, including replication experiments, and offers methodologies for interpreting variability in assemblages at the micro and macro level.
This text explores the natural history of Texas and more than 2900 springs in 183 Texas counties. It also includes an in-depth discussion of the general characteristics of springs - their physical and prehistoric settings, their historical significance, and their associated flora and fauna.
"Molecular Biology in Cellular Pathology" - Jetzt erscheint dieser erfolgreiche Klassiker in der 2. aktualisierten Auflage. Der Band beschreibt die wichtigsten Fortschritte in der Zell- und Molekularbiologie. In den letzten Jahren haben neue Erkenntnisse über den molekularen Aufbau der Zelle zur Entwicklung neuer, leistungsstarker Analysetechniken geführt, die eine größere Genauigkeit bei der Diagnose, Prognose und Behandlung von Krankheiten sowie bei der Untersuchung pathologischer Stadien ermöglichen. Insbesondere werden neue Verfahren diskutiert, die fluoreszierende Farbstoffe, DNA Microarrays, Proteinchemie und Massenspektrometrie einsetzen. Darüber hinaus enthält das Buch Informationen zum Human-Genom-Projekt und zu den neuen Disziplinen der Genomik und Proteomik, soweit diese für die Pathologie relevant sind. Neu an dieser 2. Auflage sind die Farbtafeln, die die enormen Fortschritte in der Fluoreszenz-Markierung von Zellmaterial anschaulich belegen.