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The bestselling resource on industrial chemical assessment just got better. A practical guide to biological monitoring for industrial chemical exposure assessment, the THIRD EDITION of INDUSTRIAL CHEMICAL EXPOSURE: GUIDELINES FOR BIOLOGICAL MONITORING has been completely revised to include the latest developments in the field. In addition to an update of each chapter, major revisions have been made to take into consideration new information available since the publication of the second edition. SEE WHAT'S NEW IN THE THIRD EDITION: Major changes to the sections on lead, benzene, trichloroethylene, and dimethylformamide Fourteen completely new topics: bromine, molybdenum, perchlorate, platinum, n-heptane, ethene, 1,3-butadiene trimethylbenzene, naphthalene, terpenes, acrylamide, pesticides, tetrahydrofuran, methyl tertiarybutyl ether, n-nitrosodiethylamine Discussion of the metabolic fate of chemicals Increased information on the threshold of adverse effects levels Development of biological monitoring methods for assessing the internal dose of additional chemicals This authoritative book summarizes what is known about biological monitoring for inorganic, organic and organometallic substances. It provides a summary table with practical recommendations, giving you quick and easy access to the data. With INDUSTRIAL CHEMICAL EXPOSURE: GUIDELINES FOR BIOLOGICAL MONITORING you will understand the objectives of biological monitoring, the types of biological monitoring methods, their advantages and limitations, as well as practical aspects that must be considered before initiating a biological monitoring program.
Providing material for practitioners and students alike, Chemical Exposure and Toxic Responses is a clear and straightforward presentation of industrial toxicology. Exposure to toxic chemicals is of major concern to health professionals. In recent years, the scope and importance of hazardous materials toxicology has expanded and now impacts financial institutions, government, private corporations, and many other organizations as well. Chemical Exposure and Toxic Responses presents the myriad health implications of hazardous chemicals in a single source. This book is organized so that readers can proceed from a general perspective on the problem of chemical exposure and toxic responses to an understanding of toxicology and a method of inquiry. Written for anyone who needs practical toxicological information, the book compactly and efficiently presents the scientific basis of toxicology as it applies to the workplace. It covers the diverse chemical hazards encountered in the work environment and provides a practical understanding of these hazards for those charged with protecting the health and well being of people at work. Chemical Exposure and Toxic Responses consists of three parts: Part I establishes the general principles of industrial toxicology; Part II addresses specific effects of toxic agents on specific physiological organs and systems; and Part III is devoted to the evaluation of hazards in the workplace.
A practical guide to biological monitoring for industrial chemical exposure assessment, this authoritative book summarizes what is known about biological monitoring for inorganic, organic, and organometallic substances. The authors explore the objectives of biological monitoring, the types of biological monitoring methods, their advantages and limitations, as well as practical aspects that must be considered before initiating a biological monitoring program. They identify the potential biological markers for assessing exposure or body burden and include summary tables with practical recommendations that give readers quick and easy access to the data.
The NIOSH Pocket Guide to Chemical Hazards presents information taken from the NIOSH/OSHA Occupational Health Guidelines for Chemical Hazards, from National Institute for Occupational Safety and Health (NIOSH) criteria documents and Current Intelligence Bulletins, and from recognized references in the fields of industrial hygiene, occupational medicine, toxicology, and analytical chemistry. The information is presented in tabular form to provide a quick, convenient source of information on general industrial hygiene practices. The information in the Pocket Guide includes chemical structures or formulas, identification codes, synonyms, exposure limits, chemical and physical properties, incompatibilities and reactivities, measurement methods, respirator selections, signs and symptoms of exposure, and procedures for emergency treatment.
Do you need guidelines for choosing a substitute organic solvent that is safer to use? Do you need an effective, cheap but perhaps temporary way to reduce exposures before you can convince your employer to spend money on a long-term or more reliable solution? Do you need information about local exhaust ventilation or personal protective equipment like respirators and gloves? Industrial Hygiene Control of Airborne Chemical Hazards provides the answers to these questions and more. Science-based and quantitative, the book introduces methods for controlling exposures in diverse settings, focusing squarely on airborne chemical hazards. It bridges the gap between existing knowledge of physical principles and their modern application with a wealth of recommendations, techniques, and tools accumulated by generations of IH practitioners to control chemical hazards. Provides a unique, comprehensive tool for facing the challenges of controlling chemical hazards in the workplace. Although William Popendorf has written the book at a fundamental level, he assumes the reader has some experience in science and math, as well as in manufacturing or other work settings with chemical hazards, but is inexperienced in the selection, design, implementation, or management of chemical exposure control systems. Where the book is quantitative, of course there are lots of formulae, but in general the author avoids vague notation and long derivations.
Traditionally, industrial hygienists have sought to prevent excessive exposure to chemicals in industry by setting standards for concentrations of chemicals in ambient air. Standards for chemicals in air applied by the American Conference of Governmental Industrial Hygienists include: the maximum allowable concentration (MAC), the threshold limit value (TLV), and the emergency exposure limit (EEL) However, the monitoring of air concentrations only considers exposure by inhalation and is not indicative of the actual uptake or total body burden of chemicals by exposed workers. During the past 20 years numerous procedures have been developed for the analysis of industrial chemicals in biological specimens collected from workers. Such biological monitoring takes into consideration absorption of chemicals by all routes of absorption and differences in individual exposures. The goal of biological monitoring is to detect excessive exposure in workers before the occurrence of detectable adverse health effects.
In keeping with a congressional mandate (Public Law 104-484) and the Chemical Weapons Convention, the United States is currently destroying its chemical weapons stockpile. The Army must ensure that the chemical demilitarization workforce is protected from the risks of exposure to hazardous chemicals during disposal operations and during and after facility closure. Good industrial practices developed in the chemical and nuclear energy industries and other operations that involve the processing of hazardous materials include workplace monitoring of hazardous species and a systematic occupational health program for monitoring workers' activities and health. In this report, the National Research Council Committee on Review and Evaluation of the Army Chemical Stockpile Disposal Program examines the methods and systems used at JACADS and TOCDF, the two operational facilities, to monitor the concentrations of airborne and condensed-phase chemical agents, agent breakdown products, and other substances of concern. The committee also reviews the occupational health programs at these sites, including their industrial hygiene and occupational medicine components. Finally, it evaluates the nature, quality, and utility of records of workplace chemical monitoring and occupational health programs.
The indispensable resource for health professionals on potentially unsafe chemicals--now fully updated Proctor and Hughes' Chemical Hazards of the Workplace, Fifth Edition provides a comprehensive reference text for health professionals who need toxicology data on chemicals that may be encountered in various work settings. Building on the success of the Fourth Edition-already a standard text-this new edition updates and revises the more than 600 entries of that text, and also adds monographs on new compounds. Introductory chapters cover toxicological concepts, clinical manifestations of exposure, the diagnosis of occupational disease, and industrial hygiene aspects of chemical exposures. The rest of the text consists of more than 625 alphabetically arranged entries on individual compounds, each of which includes: * Chemical formula * CAS number * 2003 ACGIH (American Conference of Government Industrial Hygienists) threshold limit value * Synonyms * Physical properties * Sources of exposure * Routes of exposure * Toxicological data The toxicological data includes both acute and chronic effects, especially as related to any known exposure levels. The data emphasizes human studies and cases over animal data whenever sufficient information is available, and addresses any known carcinogenic, mutagenic, fetotoxic, or other reproductive effects. Clinical information is presented in a succinct narrative form to aid in understanding. Easy to use, in-depth, and comprehensive, Proctor and Hughes' Chemical Hazards of the Workplace, Fifth Edition offers occupational health physicians, nurses, industrial hygienists, and other safety professionals an invaluable and up-to-date resource.
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