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Infectious diseases account for a third of all deaths in the developing world, yet the pathogens which affect specifically these predominantly poor people attract little attention. Melioidosis is a case in point. This book describes the epidemiology, pathology, pathophysiology, clinical features, diagnosis, management and prevention of an important infection that is little known outside Southeast Asia and Australia.
This book is the definitive reference regarding the global status of melioidosis in 2018. Melioidosis is one of the most neglected tropical diseases (NTDs), so much so that it is not even included in the WHO list of NTDs. Yet modeling suggests that it kills more people worldwide every year than diseases that are much better known, such as leptospirosis and dengue. The reasons for this under-recognition are numerous, including the fact that it mainly affects the disadvantaged rural poor in areas that are poorly supplied with the diagnostic capability to make the diagnosis. In 22 separate articles, expert authors from around the world have summarized what is known about the burden of the disease in humans and animals and the presence of the causative bacterium in the environment in their countries or regions. They have also identified the main obstacles and challenges to establishing the true burden, and to ensure that patients receive accurate diagnosis and optimal care for this all too frequently fatal disease. Rather than focusing on the theoretical risk of the use of Burkholderia pseudomallei as a biological weapon, this book highlights its importance as a clear and present danger to global public health.
Stiehm's Immune Deficiencies: Inborn Errors in Immunity, Second Edition, is ideal for physicians and other caregivers who specialize in immunology, allergies, infectious diseases and pulmonary medicine. It provides a validated source of information for care delivery to patients, covering approaches to diagnosis that use both new genetic information and emphasize screening strategies. Management has changed dramatically over the past five years, so approaches to infection and autoimmunity are emphasized in an effort to improve outcomes and disseminate new information on the uses of targeted therapy. - Covers immune deficiencies that are presented in a practical way, providing helpful information for active clinicians - Fills an increasingly deep gap in the information available to clinicians - Presents both clinical management and scientific advances for immune deficiencies - Provides a primary resource for physicians in the field of immunodeficiencies - Includes website access to a range of videos relevant to the topics discussed
Zoonoses are a persistent threat to the global human health Today, more than 200 diseases occurring in humans and animals are known to be mutually transmitted. Classical infectious diseases, such as rabies, plague, and yellow fever, have not been eradicated despite major efforts. New zoonotic diseases are on the increase due global conditions such as overpopulation, wars, and food scarcity, which facilitate human contact with rodents, stray animals, and their parasites. In addition, humans are unwittingly becoming accidental hosts and new links in an infectious chain by engaging in activities such as survival training, which involves camping in open areas and consumption of raw or insufficiently cooked food. Zoonotic infections cause a variety of symptoms that often do not provide clear evidence of a known disease. Zoonoses, Fourth Edition, describes most occurring worldwide zoonosis and facilitates the identification, diagnosis and treatment of zoonotic infections. Written by a team of doctors, medical microbiologists and veterinarians, this completely, revised edition covers all aspects of the epidemiology and prevention of zoonotic diseases through clear descriptions of various illnesses. Specifically, this fourth edition covers zoonosis caused by viruses, bacteria, fungi and parasites infections caused by animal bites infections and intoxications by animal foods Iatrogenic transmission of zoonotic pathogens Zoonoses is an indispensable reference for clinicians and laboratorians.
In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.
The field of occupational health and safety constantly changes, especially as it pertains to biomedical research. New infectious hazards are of particular importance at nonhuman-primate facilities. For example, the discovery that B virus can be transmitted via a splash on a mucous membrane raises new concerns that must be addressed, as does the discovery of the Reston strain of Ebola virus in import quarantine facilities in the U.S. The risk of such infectious hazards is best managed through a flexible and comprehensive Occupational Health and Safety Program (OHSP) that can identify and mitigate potential hazards. Occupational Health and Safety in the Care and Use of Nonhuman Primates is intended as a reference for vivarium managers, veterinarians, researchers, safety professionals, and others who are involved in developing or implementing an OHSP that deals with nonhuman primates. The book lists the important features of an OHSP and provides the tools necessary for informed decision-making in developing an optimal program that meets all particular institutional needs.
In response to the ever-changing needs and responsibilities of the clinical microbiology field, Clinical Microbiology Procedures Handbook, Fourth Edition has been extensively reviewed and updated to present the most prominent procedures in use today. The Clinical Microbiology Procedures Handbook provides step-by-step protocols and descriptions that allow clinical microbiologists and laboratory staff personnel to confidently and accurately perform all analyses, including appropriate quality control recommendations, from the receipt of the specimen through processing, testing, interpretation, presentation of the final report, and subsequent consultation.
This volume of the Neglected Tropical Diseases (NTD) series covers the most prevalent NTDs in Oceania. This book will discuss in detail pathology, diagnostics and control approaches of selected NTDs in the geographic region. A large part of Oceania’s population lives in poverty and therefore is at high risk for certain parasitic diseases, such as hookworm infection, lymphatic filariasis, strongyloidiasis or scabies. In addition viral infections such as dengue and new emerging viruses are of importance as major health risks for people living and traveling in this area. Each chapter focuses on one specific disease or series of related diseases, and provides in-depth insights into the topic.
The Atlas of Human Infectious Diseases provides a much needed practical and visual overview of the current distribution and determinants of major infectious diseases of humans. The comprehensive full-color maps show at a glance the areas with reported infections and outbreaks, and are accompanied by a concise summary of key information on the infectious agent and its clinical and epidemiological characteristics. Since infectious diseases are dynamic, the maps are presented in the context of a changing world, and how these changes are influencing the geographical distribution on human infections. This unique atlas: Contains more than 145 high quality full-color maps covering all major human infectious diseases Provides key information on the illustrated infectious diseases Has been compiled and reviewed by an editorial board of infectious disease experts from around the world The result is a concise atlas with a consistent format throughout, where material essential for understanding the global spatial distribution of infectious diseases has been thoughtfully assembled by international experts. Atlas of Human Infectious Diseases is an essential tool for infectious disease specialists, medical microbiologists, virologists, travel medicine specialists, and public health professionals. The Atlas of Human Infectious Diseases is accompanied by a FREE enhanced Wiley Desktop Edition - an interactive digital version of the book with downloadable images and text, highlighting and note-taking facilities, book-marking, cross-referencing, in-text searching, and linking to references and glossary terms.