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This issue of Endocrinology Clinics brings the reader up to date on the latest information about hormones and cancer of the breast and prostate. The first section focuses on the breast, and topics covered include the following. The role of sex steroids and their receptors in normal breast development; estrogen carcinogenesis in breast cancer; hormonal mechanisms underlying the relationship between obesity and breast cancer; postmenopausal hormone replacement therapy and the risk of breast cancer; aromatase inhibitors, anti-estrogen and SERMS in the treatment of breast cancer; and androgens in breast cancer in men and women. The second section is devoted to the prostate, and topics covered include the following. Overview of prostate anatomy, histology, and pathology; the critical role of sex steroids in normal prostate development; estrogens and androgens in prostate cancer development and the rationale for hormonal chemopreventive therapies; weighing the clinical evidence regarding the timing and extent of androgen ablative therapy for prostate cancer treatment; new hormonal therapies for castration-resistant prostate cancer; and the management of the side effects of castration therapy.
This issue of Endocrinology and Metabolism Clinics, Guest Edited by Dr. Vin Tangpricha, will focus on Transgender Medicine. This issue is one of four issues selected per year by the series Consulting Editor, Adriana Ioachimescu. Topics include, but are not limited to, Epidemiology of Transgender, Etiology of Gender Expression and Identity, Hormone therapy in children and adolescents, Transfeminine Hormone Therapy, Transmasculine Hormone Therapy, Dermatologic Conditions in Transgender persons, Gender Affirming Surgery, Fertility Considerations in Transgender persons, Transgender Medicine in the Military, Transgender Medicine in the Elderly, Mental Health in Transgender Persons, Primary Care in Transgender Persons, Cancer Risk in Transgender Persons, Osteoporosis, HIV in Transgender Persons, and Education Needs of Providers of Transgender Populations.
This issue of Endocrinology Clinics covers essential updates in a range of common endocrine disorders that are of special concern during pregnancy, as well as endocrine problems that can arise due to pregnancy. A variety of thyroid, pituitary, adrenal, and hypertensive disorders are covered, as well as calcium and bone metabolism disorders during pregnancy and lactation. Diagnosis and treatment of gestational diabetes, and pregestational diabetes are addressed. Iodine disorders in pregnancy and lactation are covered. Hyperprolactinemia and infertility are also addressed. Special concerns of obesity in women with reproductive dysfunction are considered. An in-depth guide to achieving a successful pregnancy with PCOS is provided
This issue of Endocrinology Clinics brings the reader up do date on the current standards and important advances in insulin therapy. The following clinical topics are discussed: types of insulins, including new insulins; goals of therapy; pathophysiology of, and insulin treatment in type1 and type 2 diabetes mellitus; pumps and glucose sensors; alternative insulin delivery; patient and provider insulin resistance; inpatient insulin therapy; insulin therapy in pregnancy; and pediatric insulin therapy.
This issue of Endocrinology Clinics, authored by experts worldwide, provides essential updates about insulin-like growth factors (IGFs). The physiology is examined, including the latest in what we have learned from animal models as well as humans. The issue also covers IGFs and IGF system in the following: growth disorders; adipogenesis and obesity; muscle function and disease; bone; cancer; cardiac function and disease; normal and diseased kidney; peripheral nervous systems; gastrointestinal diseases; diabetes and metabolism; and IGF-1 central/degenerative diseases.
This issue of Endocrinology and Metabolism Clinics will cover Pituitary Disorders. Curated by Dr. Niki Karavitaki, this issue will explore topics in the field that are relevant for practicing clinicians. This issue is one of four selected each year by the series Consulting Editor, Adriana G. Ioachimescu. The volume will include articles on: Epidemiology of pituitary disease, Advances in the imaging of pituitary tumours, WHO 2017 classification of pituitary tumours, Cancer immunotherapy and pituitary function, Advances in the medical treatment of Cushing's disease, Nelson's syndrome, Update on genetics of pituitary tumours, Dopamine agonists for pituitary tumours: benefits and risks, Acromegaly: Update on management and long-term morbidities, Endoscopic surgery for pituitary tumours, Aggressive pituitary adenomas and carcinomas, Diabetes insipidus: an update, Management of hypothalamic obesity, and Pituitary Centers of Excellence.
Although transgender persons have been present in various societies throughout human history, it is only during the last several years that they have become widely acknowledged in our society and their right to quality medical care has been established. In the United States, endocrinologists have been providing hormonal therapy for transgender individuals for decades; however, until recently, there has been only limited literature on this subject, and non-endocrine aspects of medical care for transgender individual have not been well addressed in the endocrine literature. The goal of this volume is not only to address the latest in hormonal therapy for transgender individuals (including pediatric and geriatric age groups), but also to familiarize the reader with other aspects of transgender care, including primary and surgical care, fertility preservation, and the management of HIV infection. In addition to medical issues, psychological, social, ethical and legal issues pertinent to transgender individuals add to the complexities of successful treatment of these patients. A final chapter includes extensive additional resources for both transgender patients and providers. Thus, an endocrinologist providing care to a transgender person will be able to use this single resource to address most of the patient’s needs. While Transgender Medicine is intended primarily for endocrinologists, this book will be also useful to primary care physicians, surgeons providing gender-confirming procedures, mental health professionals participating in the care of transgender persons, and medical residents and students.
This issue of Endocrinology and Metabolism Clinics of North America is devoted to Reproductive Endocrinology. Guest Editors Peter Lee, MD and Christopher P. Houk, MD have assembled a group of expert authors to review the following topics: Fertility Among Females and Males with Congenital Adrenal Hyperplasia (21-Hydroxylase Deficiency); Reproductive Issues for Turner Syndrome; Fertility and Reproduction Among Childhood Cancer Survivors; Fertility After Crypotochidism; Male Obesity and Fertility; Fertility Issues among Transgender Individuals; Fertility Preservation in Pediatrics; Polycystic Ovary Syndrome (PCOS); Fertility Issues for Patients With Delayed Puberty (Constitutional Delay, Functional Delay, and Hypogonadotropism); Varicocele; Testis Development and Reproduction in Klinefelters Syndrome; and Fertility Issues Among Those With Disorders of Sex Development.
This issue of Endocrinology and Metabolism Clinics, edited by Drs. Nanette Santoro and Lubna Pal, is devoted to Postmenopausal Endocrinology. Articles in this issue include: Endocrinology of Menopause; Menopausal Symptoms; Bone Health and Osteoporosis; Surgical Menopause; Premature Menopause; Cardiovascular Changes; MHT: Current Considerations; Breast Cancer and Hormones; Other Cancers and Menopause; CAM for Menopausal Symptoms; Menopause and Sexuality; and Menopause and Metabolism.
In this issue of Endocrinology and Metabolism Clinics of North America, guest editor Dr. Pauline Camacho brings her considerable expertise to the topic of Updates on Osteoporosis. Top experts in the field cover the latest updates in therapies, management, and guidelines for osteoporosis, in addition to updates on FRAX tools, promising agents, and anabolic agents. - Contains 11 relevant, practice-oriented topics including treatment of osteoporosis in chronic kidney disease population; prevention and management of post-denosumab rebound; optimal management of osteoporosis in the spinal cord population; workup and management of premenopausal osteoporosis; and more. - Provides in-depth clinical reviews on osteoporosis, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.