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A fascinating cornucopia of new ideas, based on fundamentals of neurobiology, psychology, psychiatry and therapy, this book extends boundaries of current concepts of consciousness. Its eclectic mix will simulate and challenge not only neuroscientists and psychologists but entice others interested in exploring consciousness. Contributions from top researchers in consciousness and related fields project diverse ideas, focused mainly on conscious nonconscious interactions: 1. Paving the way for new research on basic scientific - physiological, pharmacological or neurochemical - mechanisms underpinning conscious experience (‘bottom up’ approach); 2. Providing directions on how psychological processes are involved in consciousness (‘top down’ approach); 3. Indicating how including consciousness could lead to new understanding of mental disorders such as schizophrenia, depression, dementia, and addiction; 4. More provocatively, but still based on scientific evidence, exploring consciousness beyond conventional boundaries, indicating the potential for radical new thinking or ‘quantum leaps’ in neuroscientific theories of consciousness. (Series B)
This edited volume includes five chapters detailing recent advancements in neuroscience research. Chapter One provides a comprehensive overview of the role of caspase in neurological diseases. Chapter Two discusses both the beneficial and neurotoxic effects of β-Sitosterol β-D-Glucoside. Chapter Three describes technological innovations in therapy for childhood apraxia of speech, including the verbal motor learning method. Chapter Four details the neuroprotective properties of glycosaminoglycans. Lastly, Chapter Five elucidates the role of the hippocampal network in the brain.
Physiotherapy and rehabilitation applications in neurological diseases are important for the treatment of the disease. The basic principle of physiotherapy and rehabilitation is to determine the needs of the patient. As such, the authors discuss the evaluation of the motor functions of neurological diseases for upper and lower extremities separately, as well as sensorial functions and cognitive functions. Next, a literature review draws attention to studies in which sex was a controlled variable, and presents data regarding sexual dimorphism in a range of aspects developed after brain injury. It is possible to document the accomplishments of different cell death mechanisms and varying degrees of inflammatory response depending on the sex, as well as the distinct susceptibilities of the sexes in terms of mechanisms of cell damage. Additionally, summary of techniques and indications related to cerebrovascular bypass surgery for aneurysmal subarachnoid hemorrhage cases is provided, maintaining that cerebral revascularization procedures should be further developed by neurosurgeons as they remain the only option of treatment for a significant number of patients. The authors review their extensive experience with indocyanine green video-angiography and FLOW 800 analysis software during the surgical removal of central nervous system tumors; in particular, they identified 5 possible applications of indocyanine green video-angiography and FLOW 800 in this field. Data is presented showing the reciprocity between the brain angiotensin II system and amphetamine exposure in the development and expression of behavioral, neurochemical and glial alterations. Particularly, this collection explores how the neuroadaptative responses and neuroinflammation evoked by the psychostimulant and depending on AT1 receptors that might resemble some features linked to different brain disorders. Lastly, a brief overview of the investigational history in research work on receptor/G-protein coupling is presented. Subsequently, the most recent experimental results in the re-establishment of [35S]GTPyS binding/immunoprecipitation assay are described.
This book contains twelve chapters describing recent advancements in neuroscience research. Chapter One summarizes the role of cerebrospinal fluid biomarkers in the health and disease of dogs. Chapter Two discusses the neuroprotective effects of erythropoietin. Chapter Three focuses on the development of several mesencephalic areas using tyrosine hydroxylase immunocytochemistry and tritiated thymidine autoradiography. Chapter Four presents a study of the cerebellum of different age members of the same family using gravitational mass spectroscopy. Chapter Five explores how the conformations of nucleosomes and their states in the spirals of solenoids are responsible for the processes of short-term and long-term memory as well as other brain functions. Chapter Six deals with cognitive decline and depression associated with severe asymptomatic carotid stenosis. Chapter Seven describes the surgical technique of extensive craniofacial reconstruction for unilateral anterior plagiocephaly treatment. Chapter Eight gives a model of the molecular cause of pain based on a study of human fingers conducted via gravitational mass spectroscopy. Chapter Nine deals with the role of globules in the work of the brain and the dynamics of their conformations. Chapter Ten explains how chromosome topology is formed in vivo. Chapter Eleven explores the relationship between mild traumatic brain injury and residual cognitive impairment. Finally, Chapter Twelve examines stochastic resonance in the context of human sensory systems.
The authors' of this book discuss the most recent advances in neuroscience research. The chapters include updated information on clinical and technical implementation of digital subtraction angiography (DSA) in stroke imaging; association between word display and executive functioning; the connectivity between the cerebellum and inferior frontal gyrus (IFG); the identification and validation of EEG, MRI and SPECT biomarkers for diagnosing, monitoring progression and predicting the onset of Alzheimer's disease (AD); an examination of the leptin receptor, a drive of adult neurogenesis that may treat Alzheimer's disease; the language of neurons and their clinical applications such as in deep brain stimulation; the use of folic acid and its intake by pregnant women to support both physiological changes in the mother and the optimal growth and development of the fetus and offspring; examples of the continuum of shapes and sizes of different dendritic spines, from simple to complex, observed in the human brain; an examination of spastic diplegia, the most common form of cerebral palsy; and the identification of new mechanisms of pharmacological effects of certain neurotropic peptides.
This compilation provides some updates in the field of neuroscience research. Chapter One collects up-to-date research on post-traumatic stress disorder (PTSD) and elucidates the temporal development of this disorder. Chapter Two explains the role of lipid peroxidation in the development of hydrocephalic astrogliosis. Chapter Three is devoted to the effect of pyrimidine derivatives on changes in mitochondrial function in rats under conditions of permanent cerebral ischemia. Chapter Four investigates the relationship between PTSD and the brain's spatio-temporal dynamics through an experimental study on mice. Chapter Five provides an overview on studies to treat social cognition disturbances in mental disorders such as schizophrenia with transcranial direct current stimulation and discusses its neurobiological mechanisms. Finally, Chapter Six deals with the role of nucleosome ensembles in the control of the visual apparatus as a neuro controller in the operative work of the brain as a whole.
Human greatness has many connotations. Since the requirements for membership in this category are vague and poorly defined, admittance to the Mount Olympus is frequently erratic and subjective, especially in view of a wide "penumbra zone"* of border cases. Nevertheless, rising above a twilight zone of debatable cases, there are individuals whose right for mem bership is unquestionable. In science, one of the unequivocal criteria for "greatness" relates to how far one's scientific achievement affects the opening of new horizons, and points to directions for future development and progress. Unveiling new visions can derive only from creative people who conceive original ideas and con cepts, and who are daring enough to promote them against the indifference or opposition of the establishment. Maintaining the integrity and the faith to one's own ideals may require extraordinary strength of character, - up to courting persecution or even death, - as happened in the middle ages, and more recently, in the first half of this century with regard to Cecile and Os kar Vogt, whose lives and accomplishments are described in this book. Thus the greatness of the Vogts is based both on their penetrating vision of the future for brain research and on the sterling quality of their character, which sustained a "test of fire" during the Nazi years in Germany.
The journey of Mind Sciences in India has been through the peaks and troughs. It is generally accepted that no other cultural tradition except Indian has given so much attention to the matters of mind and consciousness. Yet, recognition to the sciences studying mind like psychology as a scientific discipline came in very late. There were only a handful of universities in India which had independent departments of psychology or neuroscience at the time of Indias independence. In the last few decades, mind sciences in the country have picked up steam resulting in major discussions and interactions across disciplines like psychology, neuroscience and computer science. This book examines the expanding horizons of the mind sciences.