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A complete reference to the cutting edge procedures used to test today's materials and details measuring techniques for the long term durability of new types of concrete and concrete technologies, with contributions by 24 leading scientists and chapters that cover chemical and thermal analysis.
Handbook of Analytical Quality by Design addresses the steps involved in analytical method development and validation in an effort to avoid quality crises in later stages. The AQbD approach significantly enhances method performance and robustness which are crucial during inter-laboratory studies and also affect the analytical lifecycle of the developed method. Sections cover sample preparation problems and the usefulness of the QbD concept involving Quality Risk Management (QRM), Design of Experiments (DoE) and Multivariate (MVT) Statistical Approaches to solve by optimizing the developed method, along with validation for different techniques like HPLC, UPLC, UFLC, LC-MS and electrophoresis. This will be an ideal resource for graduate students and professionals working in the pharmaceutical industry, analytical chemistry, regulatory agencies, and those in related academic fields. - Concise language for easy understanding of the novel and holistic concept - Covers key aspects of analytical development and validation - Provides a robust, flexible, operable range for an analytical method with greater excellence and regulatory compliance
Written for practitioners in both the drug and biotechnology industries, this handbook carefully compiles the current regulatory requirements to correctly and properly validate a new or modified analytical method. The Handbook of Analytical Validation is designed to teach readers how to fully and correctly adapt new or modified analytical methods to meet regulatory requirements. The contents offer the latest regulatory requirements for submitting applications for new drugs or other applications, as regards analytical method validation. The chapters apply to both small molecules in the conventional pharmaceutical industry, as well the biotech industry.
"Highlights include: an in-depth review of how analytical methods for dietary supplements are validated, including information on what buyers of analytical services should look for and how they should assess the quality of results. This review is useful to those validating their own in-house methods, as well; 38 monographs on dietary ingredients most commonly used to produce dietary supplements. Each monograph follows a standard format for quick reference; chemical names, formulas, and structures, along with information on solubility and other physical and chemical data; a description of common uses for each dietary supplement and its mode of action; discussion of reference standards and/or marker compounds used; information and directions for using various component-specific methods; and chromatography specifications and representative chromatograms, when available."--BOOK JACKET.
Bioanalytical Separations is volume 4 of the multi-volume series, Handbook of Analytical Separations, providing reviews of analytical separation methods and techniques used for the determination of analytes across a whole range of applications. The theme for this volume is bioanalysis, in this case specifically meaning the analysis of drugs and their metabolites in biological fluids.- Discusses new developments in instrumentation and methods of analyzing drugs and their metabolites in biological fluids - Provides guidance to the different methods, their relative value to the user, and the advantages and pitfalls of their use - Future trends are identified, in terms of the potential impact of new technologies
(Parent with price) Volume I contains subjective reviews, specialized and novel technique descriptions by guest authors. Part 1 includes contributions on purely analytical techniques and Part 2 includes matters such as development of mass spectrometers, stability of ion sources, standards and calibration, correction procedures and experimental methods to obtain isotopic fractionation factors.Volume II will be available in 2005.
With this handbook, these users can find information about the most common analytical chemical techniques in an understandable form, simplifying decisions about which analytical techniques can provide the information they are seeking on chemical composition and structure.
Handbook of Advanced Chromatography /Mass Spectrometry Techniques is a compendium of new and advanced analytical techniques that have been developed in recent years for analysis of all types of molecules in a variety of complex matrices, from foods to fuel to pharmaceuticals and more. Focusing on areas that are becoming widely used or growing rapidly, this is a comprehensive volume that describes both theoretical and practical aspects of advanced methods for analysis. Written by authors who have published the foundational works in the field, the chapters have an emphasis on lipids, but reach a broader audience by including advanced analytical techniques applied to a variety of fields. Handbook of Advanced Chromatography / Mass Spectrometry Techniques is the ideal reference for those just entering the analytical fields covered, but also for those experienced analysts who want a combination of an overview of the techniques plus specific and pragmatic details not often covered in journal reports. The authors provide, in one source, a synthesis of knowledge that is scattered across a multitude of literature articles. The combination of pragmatic hints and tips with theoretical concepts and demonstrated applications provides both breadth and depth to produce a valuable and enduring reference manual. It is well suited for advanced analytical instrumentation students as well as for analysts seeking additional knowledge or a deeper understanding of familiar techniques. - Includes UHPLC, HILIC, nano-liquid chromatographic separations, two-dimensional LC-MS (LCxLC), multiple parallel MS, 2D-GC (GCxGC) methodologies for lipids analysis, and more - Contains both practical and theoretical knowledge, providing core understanding for implementing modern chromatographic and mass spectrometric techniques - Presents chapters on the most popular and fastest-growing new techniques being implemented in diverse areas of research
Learn how to use 24 structured analytic techniques to overcome mindsets, structure uncertainties, leverage your imagination, reduce the chance of surprise, and instill more rigor in your analysis. Use of the techniques in growing steadily in the intelligence, homeland security, and law enforcement communities as well as in the private sector and across the globe! The Handbook of Analytic Tools and Techniques provides a definition of each technique, advice on when to use it, a description of how each adds value to the analysis, and a step-by-step description of the specific method involved. The Handbook is organized into five parts: * Innovative Techniques - Break the Mold!* Diagnostic Techniques - Crack the Code!* Reframing Techniques - Challenge Your Mindset!* Foresight Techniques - Anticipate the Future!* Decision Support Tools - Make a Plan!
Handbook of Analytical Techniques for Forensic Samples: Current and Emerging Developments discusses in detail the current trends and latest analytical techniques and methods commonly employed in forensic analysis in order to ensure the proper facilitation of justice. This book is useful for readers who wish to stay updated on the latest trends in the forensic analysis of samples encountered at crime scenes. Technological advancements, such as biosensors, nanotechnology, and taggant technology have upped the level of analysis in forensic science. These emergent technologies, incorporated with existing analytical techniques, are leading to more precise, accurate, and specific examination of forensic samples. Lab-on-a-chip technology has also eased several kinds of on-site analyses done by investigating teams at different types of crime scenes. This book covers the evolution of forensic sample analysis as well as these emerging trends and new technologies. Includes an entire section of experimental exercises for self-teaching and key concept review Covers laboratory protocols used in forensic science laboratories for the analysis of various samples through different analytical techniques Condenses the many aspects of forensic analytical chemistry into a single resource with easy-to-understand language for everyone from students to practitioners