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THE STORY: As the play begins Al (in reality the author himself) has had another opening--and another crushing set of bad notices. Discouraged and wishing he were elsewhere, Al tinkers with a bizarre time machine concocted by his roommate, Kafka (a
Gus. Losing himself. Finding himself. But he doesn't even know how to function anymore. Bright Side wasn't only his best friend; she was like his other half ... How do you go back to doing what you did before, when half of you is gone forever?
Methods of strawberry cultivation have undergone extensive modification and this book provides an up-to-date, broad and balanced scientific review of current research and emerging challenges. Subjects covered range from plant propagation, architecture, genetic resources, breeding, abiotic stresses and climate change, to evolving diseases and their control. These topics are examined in three sections: 1. Genetics, Breeding and Omics - covering genetic resources, breeding, metabolomics, transcriptomics, and genetic transformation of strawberry. 2. Cultivation Systems and Propagation - discusses plant architecture, replanting problems and plant propagation techniques. 3. Disease and Stress Management - deals with traditional and emerging fungal diseases, their diagnosis and modern biocontrol strategies, and biotechnological interventions for dealing with the challenges of climate change. Strawberry: Growth, Development and Diseases is written by an international team of specialists, using figures and tables to make the subject comprehensible and informative. It is an essential resource for academics and industry workers involved in strawberry research and development, and all those interested in the commercial cultivation of strawberries.
Biologically active small molecules have increasingly been applied in plant biology to dissect and understand biological systems. This is evident from the frequent use of potent and selective inhibitors of enzymes or other biological processes such as transcription, translation, or protein degradation. In contrast to animal systems, which are nurtured from drug research, the systematic development of novel bioactive small molecules as research tools for plant systems is a largely underexplored research area. This is surprising since bioactive small molecules bear great potential for generating new, powerful tools for dissecting diverse biological processes. In particular, when small molecules are integrated into genetic strategies (thereby defining “chemical genetics”), they may help to circumvent inherent problems of classical (forward) genetics. There are now clear examples of important, fundamental discoveries originating from plant chemical genetics that demonstrate the power, but not yet fully exploited potential, of this experimental approach. These include the unraveling of molecular mechanisms and critical steps in hormone signaling, activation of defense reactions and dynamic intracellular processes. The intention of this Research Topic of Frontiers in Plant Physiology is to summarize the current status of research at the interface between chemistry and biology and to identify future research challenges. The research topic covers diverse aspects of plant chemical biology, including the identification of bioactive small molecules through screening processes from chemical libraries and natural sources, which rely on robust and quantitative high-throughput bioassays, the critical evaluation and characterization of the compound’s activity (selectivity) and, ultimately, the identification of its protein target(s) and mode-of-action, which is yet the biggest challenge of all. Such well-characterized, selective chemicals are attractive tools for basic research, allowing the functional dissection of plant signaling processes, or for applied purposes, if designed for protection of crop plants from disease. New methods and data mining tools for assessing the bioactivity profile of compounds, exploring the chemical space for structure–function relationships, and comprehensive chemical fingerprinting (metabolomics) are also important strategies in plant chemical biology. In addition, there is a continuing need for diverse target-specific bioprobes that help profiling enzymatic activities or selectively label protein complexes or cellular compartments. To achieve these goals and to add suitable probes and methods to the experimental toolbox, plant biologists need to closely cooperate with synthetic chemists. The development of such tailored chemicals that beyond application in basic research can modify traits of crop plants or target specific classes of weeds or pests by collaboration of applied and academic research groups may provide a bright future for plant chemical biology. The current Research Topic covers the breadth of the field by presenting original research articles, methods papers, reviews, perspectives and opinions.
Critically acclaimed author Cammie McGovern presents a heartwarming and humorous middle grade novel about the remarkable bond that forms between an aspiring service dog and an autistic boy in need of a friend. “Joyful, inspiring, and completely winning, Chester and Gus is unforgettable,” proclaimed Katherine Applegate, #1 New York Times bestselling author of the Newbery Medal winner The One and Only Ivan. Chester has always wanted to become a service dog. When he fails his certification test, though, it seems like that dream will never come true—until a family adopts him. They want him to be a companion for their ten-year-old son, Gus, who has autism. But Gus acts so differently than anyone Chester has ever met. He never wants to pet Chester, and sometimes he doesn’t even want Chester in the room. Chester’s not sure how to help Gus since this isn’t exactly the job he trained for—but he’s determined to figure it out. Because after all, Gus is now his person. In the spirit of beloved classics like Because of Winn-Dixie, Shiloh, and Old Yeller, Cammie McGovern’s heartfelt novel—told from Chester’s point of view—explores the extraordinary friendship between a child and a dog with a poignant and modern twist.
The improvement of crop species has been a basic pursuit since cultivation began thousands of years ago. To feed an ever increasing world population will require a great increase in food production. Wheat, corn, rice, potato and few others are expected to lead as the most important crops in the world. Enormous efforts are made all over the world to document as well as use these resources. Everybody knows that the introgression of genes in wheat provided the foundation for the “Green Revolution”. Later also demonstrated the great impact that genetic resources have on production. Several factors are contributing to high plant performance under different environmental conditions, therefore an effective and complementary use of all available technological tools and resources is needed to meet the challenge.
Advances in Food and Nutrition Research
Returning home after serving World War II to run his family business in New York, a paratrooper falls in love with a young heiress and actress he meets on the State Island ferry.
From the pre-historic era to modern times, cereal grains have been the most important source of human nutrition, and have helped sustain the increasing population and the development of human civilization. In order to meet the food needs of the 21st century, food production must be doubled by the year 2025, and nearly tripled by 2050. Such enormous increases in food productivity cannot be brought about by relying entirely on conventional breeding methods, especially on less land per capita, with poor quality and quantity of water, and under rapidly deteriorating environmental conditions. Complementing and supplementing the breeding of major food crops, such as the cereals, which together account for 66% of the world food supply, with molecular breeding and genetic manipulation may well provide a grace period of about 50 years in which to control population growth and achieve sustainable development. In this volume, leading world experts on cereal biotechnology describe the production and commercialization of the first generation of transgenic cereals designed to substantially reduce or prevent the enormous losses to cereal productivity caused by competition with weeds, and by various pests and pathogens, which is an important first step in that direction.