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This book, now in an extensively revised second edition, summarizes the basic principles of nuclear medicine and describes the clinical applications of commonly used nuclear medicine procedures and techniques. Readers will find clear explanation of clinical indications, the pathophysiological basis of functional procedures, and the complementary role of nuclear medicine and molecular imaging in relation to diagnostic radiology. Throughout, emphasis is placed on the added diagnostic value offered by the new hybrid imaging modalities. The various therapeutic applications of nuclear medicine are also discussed. Compared with the first edition, technical details have been significantly simplified. The book will be an ideal introduction to nuclear medicine for medical students and will serve as an excellent quick reference for referring physicians, enabling them to utilize this modern medical specialty more efficiently.
The thoroughly updated new edition of the authoritative reference in Radiopharmaceutical Sciences The second edition of Handbook of Radiopharmaceuticals is a comprehensive review of the field, presenting up-to-date coverage of central topics such as radionuclide production, synthetic methodology, radiopharmaceutical development and regulations, and a wide range of practical applications. A valuable reference work for those new to the Radiopharmaceutical Sciences and experienced professionals alike, this volume explores the latest concepts and issues involving both targeted diagnostic and therapeutic radiopharmaceuticals. Contributions from a team of experts from across sub-disciplines provide readers with an immersive examination of radiochemistry, nuclear medicine, molecular imaging, and more. Since the first edition of the Handbook was published, Nuclear Medicine and Radiopharmaceutical Sciences have undergone major changes. New radiopharmaceuticals for diagnosis and therapy have been approved by the FDA, the number of clinical PET and SPECT scans have increased significantly, and advances in Artificial Intelligence have dramatically improved research techniques. This fully revised edition reflects the current state of the field and features substantially updated and expanded content. New chapters cover topics including current Good Manufacturing Practice (cGMP), regulatory oversight, novel approaches to quality control—ensuring that readers are informed of the exciting developments of recent years. This important resource: Features extensive new and revised content throughout Covers key areas of application for diagnosis and therapy in oncology, neurology, and cardiology Emphasizes the multidisciplinary nature of Radiopharmaceutical Sciences Discusses how drug companies are using modern radiopharmaceutical imaging techniques to support drug discovery Examines current and emerging applications of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Edited by recognized experts in radiochemistry and PET imaging, Handbook of Radiopharmaceuticals: Radiochemistry and Applications, 2 nd Edition is an indispensable reference for post-doctoral fellows, research scientists, and professionals in the pharmaceutical industry, and for academics, graduate students, and newcomers in the field of radiopharmaceuticals.
This publication is an excellent introduction to the diagnostic and therapeutic uses of nuclear medicine procedures and a must have for clinicians, residents, interns, medical students and referring physicians. It reviews nuclear medicine procedures, available alternatives, advantages and limitations of each, and provides patient information to aid in preparing patients
Medical imaging is crucial in a variety of medical settings and at all levels of health care. In public health and preventive medicine as well as in both curative and palliative care, effective decisions depend on correct diagnoses. This edition addresses the most current needs and offers guidance on clinical practice, radiation safety and patient protection, human resource development and training required for the overall practice of nuclear medicine.
A comprehensive, authoritative and up-to-date reference for the newcomer to radiopharmaceuticals and those already in the field. Radiopharmaceuticals are used to detect and characterise disease processes, or normal biological function, in living cells, animals or humans. Used as tracer molecules, they map the distribution, uptake and metabolism of the molecule in clinical studies, basic research or applied research. The area of radiopharmaceuticals is expanding rapidly. The number of PET centers in the world is increasing at 20% per year, and many drug companies are utilising PET and other forms of radiopharmaceutical imaging to evaluate products. * Readers will find coverage on a number of important topics such as radionuclide production, PET and drug development, and regulations * Explains how to use radiopharmaceuticals for the diagnosis and therapy of cancer and other diseases * The editors and a majority of the contributors are from the United States
Radioimmunotherapy, also known as systemic targeted radiation therapy, uses antibodies, antibody fragments, or compounds as carriers to guide radiation to the targets. It is a topic rapidly increasing in importance and success in treatment of cancer patients. This book represents a comprehensive amalgamation of the radiation physics, chemistry, radiobiology, tumor models, and clinical data for targeted radionuclide therapy. It outlines the current challenges and provides a glimpse at future directions. With significant advances in cell biology and molecular engineering, many targeting constructs are now available that will safely deliver these highly cytotoxic radionuclides in a targeted fashion. A companion website includes the full text and an image bank.
A tactical guide for radiologists and nuclear medicine physicians, Diagnostic Imaging: Nuclear Medicine, Second Edition is practical, easy-to-use, and in-touch with the realities of multimodality diagnostic imaging. This comprehensive yet accessible reference addresses the most appropriate nuclear medicine options available to answer specific clinical questions within the framework of all imaging modalities. Sweeping updates include a complete reorganization, new differential diagnoses based on findings, and new chapters on physics and Nuclear Regulatory Commission guidelines. User-friendly bulleted text and a uniform chapter layout allow fast and effortless access to the crucial knowledge you need! Time-saving reference features include bulleted text, a variety of test data tables, key facts in each chapter, 2,000 full-color annotated images, and an extensive index Expanded coverage of the most important topics and trends in nuclear medicine including Recently revised radioactive iodine therapy guidelines for hyperthyroidism and thyroid cancer New bone tumor therapy radium-223 (currently indicated for treatment of painful bone metastases in prostate cancer) New I-123 ioflupane dopamine transporter imaging for diagnosis of parkinsonian syndromes F-18 PET/CT bone scan (particularly its indication for nonaccidental trauma in children) Meticulous updates throughout reflect the latest advances as well as all study guide topics listed for the new American Board of Radiology exam, including physics and Nuclear Regulatory Commission guidelines Expert Consult eBook version included with purchase allows you to search all of the text, figures, and references from the book on a variety of devices
The gold standard text-reference Diagnostic Nuclear Medicine is now in its Fourth Edition--with a sharp clinical focus, a streamlined new single-volume format, and a very attractive price. Written by the top authorities in the specialty, this brand-new edition offers encyclopedic coverage of clinically relevant developments in nuclear medicine--including instrumentation, radiopharmaceuticals, and applications. Readers will find the latest on PET, molecular imaging, SPECT myocardial perfusion imaging, monoclonal antibody therapy, and the use of functional imaging studies in oncology. This edition has been trimmed from two volumes to one, so that readers can find exactly what they need quickly, without cross-checking between volumes.