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While the collapse of the Soviet Union has diminished the force of George Orwell's 1984, the other great dystopian tract of the twentieth century, Alduous Huxley's Brave New World, is timelier than ever. The ongoing process of genetic science may well revolutionize medicine and human reproduction, and it may end by giving us the ability to transform the human species itself. This new power has raised hopes that we will solve a range of genetically based problems that afflict us. It has also evoked fears that we are on the verge of a 'post human' future in which precious but necessary norms regulating individual and social life will be set aside. Will we have the moral and political wisdom to avoid the pitfalls in using new biotechnologies? Genetic Prospects considers the resources from which the needed norms and maxims might be drawn, scrutinizing carefully the contributions of common sense, religion, and moral sentiment. Taken together, the essays in this volume apply philosophical analysis to address three kinds of questions: What are the implications of genetic science for our understanding of nature? What might it influence in our conception of human nature? What challenges does genetic science poses for specific issues of private conduct or public policy?
Genetically engineered (GE) crops were first introduced commercially in the 1990s. After two decades of production, some groups and individuals remain critical of the technology based on their concerns about possible adverse effects on human health, the environment, and ethical considerations. At the same time, others are concerned that the technology is not reaching its potential to improve human health and the environment because of stringent regulations and reduced public funding to develop products offering more benefits to society. While the debate about these and other questions related to the genetic engineering techniques of the first 20 years goes on, emerging genetic-engineering technologies are adding new complexities to the conversation. Genetically Engineered Crops builds on previous related Academies reports published between 1987 and 2010 by undertaking a retrospective examination of the purported positive and adverse effects of GE crops and to anticipate what emerging genetic-engineering technologies hold for the future. This report indicates where there are uncertainties about the economic, agronomic, health, safety, or other impacts of GE crops and food, and makes recommendations to fill gaps in safety assessments, increase regulatory clarity, and improve innovations in and access to GE technology.
Why do we behave the way we do? Biologist Paul Ehrlich suggests that although people share a common genetic code, these genes "do not shout commands at us...at the very most, they whisper suggestions." He argues that human nature is not so much result of genetic coding; rather, it is heavily influenced by cultural conditioning and environmental factors. With personal anecdotes, a well-written narrative, and clear examples, Human Natures is a major work of synthesis and scholarship as well as a valuable primer on genetics and evolution that makes complex scientific concepts accessible to lay readers.
Addressing the pear genome, this book covers the current state of knowledge regarding genetic and genomic resources, breeding approaches and strategies, as well as cutting-edge content on how these tools and resources are being / soon will be utilized to pursue genetic improvement efforts that will combine fruit quality, high productivity, precocious fruit bearing, and long postharvest storage life, along with elevated levels of resistance to various major diseases and insect pests. Throughout, the book also explores potential opportunities and challenges in genomic analysis, sequence assembly, structural features, as well as functional studies that will assist in future genetic improvement efforts for pears. The pear (Pyrus), an important tree fruit crop, is grown worldwide, and has several economically relevant cultivars. In recent years, modern genetic and genomic tools have resulted in the development of a wide variety of valuable resources for the pear. In the past few years, completion of whole genome assemblies of ‘Dangshansuli’, an Asian pear, and ‘Bartlett’, a European pear, have paved the way for new discoveries regarding for example, the pear’s genomic structure, chromosome evolution, and patterns of genetic variation. This wealth of new resources will have a major impact on our knowledge of the pear genome; in turn, these resources and knowledge will have significant impacts on future genetic improvement efforts.
Raising hopes for disease treatment and prevention, but also the specter of discrimination and "designer genes," genetic testing is potentially one of the most socially explosive developments of our time. This book presents a current assessment of this rapidly evolving field, offering principles for actions and research and recommendations on key issues in genetic testing and screening. Advantages of early genetic knowledge are balanced with issues associated with such knowledge: availability of treatment, privacy and discrimination, personal decision-making, public health objectives, cost, and more. Among the important issues covered: Quality control in genetic testing. Appropriate roles for public agencies, private health practitioners, and laboratories. Value-neutral education and counseling for persons considering testing. Use of test results in insurance, employment, and other settings.
Genetics of Bone Biology and Skeletal Disease, Second Edition, is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder. The book is organized into five sections that each emphasize a particular theme, general background to bone biology, general background to genetics and epigenetics, disorders of bone and joint, parathyroid and related disorders, and vitamin D and renal disorders. The first section is specifically devoted to providing an overview of bone biology and structure, joint and cartilage biology, principles of endocrine regulation of bone, and the role of neuronal regulation and energy homeostasis. The second section reviews the principles and progress of medical genetics and epigenetics related to bone disease, including genome-wide association studies (GWAS), genomic profiling, copy number variation, prospects of gene therapy, pharmacogenomics, genetic testing and counseling, as well as the generation and utilizing of mouse models. The third section details advances in the genetics and molecular biology of bone and joint diseases, both monogenic and polygenic, as well as skeletal dysplasias, and rarer bone disorders. The fourth section highlights the central role of the parathyroids in calcium and skeletal homeostasis by reviewing the molecular genetics of: hyperparathyroidism, hypoparathyrodism, endocrine neoplasias, and disorders of the PTH and calcium-sensing receptors. The fifth section details molecular and cellular advances across associated renal disorders such as vitamin D and rickets. - Identifies and analyzes the genetic basis of bone disorders in humans and demonstrates the utility of mouse models in furthering the knowledge of mechanisms and evaluation of treatments - Demonstrates how the interactions between bone and joint biology, physiology, and genetics have greatly enhanced the understanding of normal bone function as well as the molecular pathogenesis of metabolic bone disorders - Summarizes the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder
Discover the fascinating world of genetics in this comprehensive and engaging guide, which delves into the very core of life itself. From the simplest organisms to the complexities of the human body, this book unravels the mysteries of heredity, molecular biology, and evolution, providing readers with a deeper understanding of the intricate workings of life. Written in a friendly and conversational tone, this guide is designed to be accessible to readers of all backgrounds, from curious novices to seasoned enthusiasts. Subtle humor is sprinkled throughout, making the learning experience both enjoyable and informative. Each chapter is meticulously crafted to build upon the previous one, ensuring a coherent and captivating journey through the world of genetics. In this book, you will explore the history of genetic research, from Mendel's groundbreaking work with pea plants to the awe-inspiring advances in biotechnology and genome editing. Along the way, you will encounter the renowned scientists who have shaped our understanding of genetics, and gain insights into the ethical considerations that accompany the ever-evolving field. You will also discover key terms and concepts that will help you navigate the complex world of genetics, as well as additional resources to further your understanding and satisfy your curiosity. This book will inspire you to delve deeper into the subject, spark your imagination, and fuel your passion for genetics. Embark on an extraordinary journey through the microscopic world that lies at the heart of every living organism, and unlock the secrets that govern the blueprint of life. This book will leave you with a newfound appreciation for the incredible science of genetics and the wonders of the natural world.
This unique book covers the molecular aspects of plant stress and the various industrial applications. Chapters cover many important topics in the biology of plant stress, including morphological and physiological changes of plants due to accumulation of pollutants; the types of stress for enhanced biofuel production from plant biomass; plant adaptation due to different types of environmental stresses; potential applications of microRNAs to improve abiotic stress tolerance in plants; plant resistance to viruses and the molecular aspects; photosynthesis under stress conditions; plant responses to weeds, pests, pathogens, and agrichemical stress conditions; and plant responses under the stress of drought. Key features: • Describes the different types of plant stress • Details the current and possible applications of plant stress biology • Presents several case studies that include applications of plant stress • Explores plant stress biology for applications in biofuel science Plant Stress Biology: Progress and Prospects of Genetic Engineering will be useful for researchers in diverse fields as well as for plant biologists, environmental biologists, faculty, and students. The book will also be helpful for further advancement of research in the area of plant stress biology.