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This book focuses on an increasingly important area of materials science and technology, namely, the fabrication and properties of artificial materials where slabs of magnetized materials are sandwiched between slabs of nonmagnetized materials. It includes reviews by experts on the theory and descriptions of the various experimental techniques such as those using nuclear or electron spin probes, as well as optical, X-ray or neutron probes. It also reviews potential applications such as the giant magnetoresistance, and one specialized preparation technique, the electrodeposition. The various chapters are tutorial in nature, making the subject accessible to nonspecialists, as well as useful to researchers in the field.
The book series Nanomaterials for the Life Sciences, provides an in-depth overview of all nanomaterial types and their uses in the life sciences. Each volume is dedicated to a specific material class and covers fundamentals, synthesis and characterization strategies, structure-property relationships and biomedical applications. The series brings nanomaterials to the Life Scientists and life science to the Materials Scientists so that synergies are seen and developed to the fullest. Written by international experts of various facets of this exciting field of research, the series is aimed at scientists of the following disciplines: biology, chemistry, materials science, physics, bioengineering, and medicine, together with cell biology, biomedical engineering, pharmaceutical chemistry, and toxicology, both in academia and fundamental research as well as in pharmaceutical companies. VOLUME 4 - Magnetic Nanomaterials This volume takes the reader on a tour showing how magnetic nanomaterials are used in the fields of diagnosis and therapy, as well as in tissue engineering and environmental applications.
Explores a Range of Multiscale Biomechanics/Mechanobiology ConceptsCell and Matrix Mechanics presents cutting-edge research at the molecular, cellular, and tissue levels in the field of cell mechanics. This book involves key experts in the field, and covers crucial areas of cell and tissue mechanics, with an emphasis on the roles of mechanical forc
This book presents the results of the project on Young Adults with Low Levels of Education, conducted jointly by the OECD and the Canadian Policy Research Networks.
This book focuses on the reciprocal interactions between pain, emotion and cognition. International experts report on their findings, clinical experience and the most recent literature on the complex relations between these three domains. Clinical, psychological, behavioral and neuroimaging approaches converge towards aiding patients suffering from pain, cognitive impairment or emotional distress. Beyond the pathophysiological aspects of pain, difficulties encountered with patients are analyzed and strategies are proposed to optimize treatment, doctor-patient relationships, and patient well-being. This work will appeal to a broad readership, from clinical medical practitioners to psychologists, nurses and pain specialists.
This book provides a compelling overall update on current status of RNA interference
Insects, being poikilothermic, are among the organisms that are most likely to respond to changes in climate, particularly increased temperatures. Range expansions into new areas, further north and to higher elevations, are already well documented, as are physiological and phenological responses. It is anticipated that the damage by insects will increase as a consequence of climate change, i.e. increasing temperatures primarily. However, the evidence in support of this common “belief” is sparse. Climate Change and Insect Pests sums up present knowledge regarding both agricultural and forest insect pests and climate change in order to identify future research directions.
This thorough and informative volume presents a set of detailed, globally applicable techniques for seagrass research.The book provides methods for all aspects of seagrass science from basic plant collection to statistical approaches and investigations of plant-animal interaction. The emphasis is on methods that are applicable in both developing and developed countries. The importance of seagrasses in coastal and near shore environments, and ultimately their contribution to the productivity of the world's oceans, has become increasingly recognised over the last 40 years.Seagrasses provide food for sea turtles, nearly 100 fish species, waterfowl and for the marine mammals the manatee and dugong. Seagrasses also support complex food webs by virtue of their physical structure and primary production and are well known for their role as breeding grounds and nurseries for important crustacean, finfish and shell fish populations. Seagrasses are the basis of an important detrital food chain. The plants filter nutrients and contaminants from the water, stabilise sediments and act as dampeners to wave action. Seagrasses rank with coral reefs and mangroves as some of the world's most productive coastal habitat and strong linkages among these habitats make the loss of seagrasses a contributing factor in the degradation of the world's oceans.Contributors from around the world provide up-to-date methods for comparable collection of ecological information from both temperate and tropical seagrass ecosystems.
Human aging is perhaps the most complex and important subject that will be facing science and societies in the next century. Persons seem to be living longer and remaining more active than their parents and grandparents. This is leading to social and demographic shifts that must be accommodated by society. On the other hand it presents perplexing questions about the underlying processes and determinants of healthy aging. This book gives a design for research that will increase our understanding of the factors that influence healthy aging and can lead to improvements in reducing the levels of disability in the population. It's focus is on biobehavioural and psychological factors contributing to healthy aging. Since human aging is determined by many interacting conditions inside and outside of the organism, research should concentrate on ecological relationships between the human organism and its social and physical environment. Not only individual characteristics associated with aging are discussed in this book, but also their impacts on society. Living longer means most persons will have fewer years to earn money to maintain their lives in a longer retirement. How can these two forces be resolved through public policy? At the same time greater competence in the later years needs clues to ways of releasing this productivity for the benefit of society and individuals. Adding healthy life expectancy and creating as much as possible disability-free years is a goal that can only be reached through fact finding by a multidisciplinary team of scientist collaborating on an international basis. Such a team is present in the collaborators represented in this book. The information presented in 'Aging in Europe' has not been available in any single source before. In many ways this book provides a model of gaining knowledge through cooperation that should guide us in the next century and beyond.
The use of oligonucleotides as therapeutic agents rests upon their ability to interfere, in a sequence-specific manner, with the fundamental machinery of protein synthesis either by binding to the mRNAs transcribed from a gene or by binding directly to a target gene. This approach can be used not only for inhibition of the synthesis of host proteins but also of those required by invading pathogens. Potential therapeutic applications are enormous, ranging over hypertension, cardiovascular disease, autoimmune disease, vital and other parasitic infections (especially HIV), and cancer. This book discusses the chemistry and pharmacokinetics of oligonucleotides and their analogues, and surveys the results of structure-activity studies and current clinical trials. It also critically reviews the problems with antisense therapy, such as the enzymatic destruction of oligonucleotides, the doses required for a therapeutic response, the difficulty in directing oligonucleotides to particular target tissues and cells, the need for parenteral administration, and doubts concerning the mechanism of action (especially problems associated with non-specific binding to proteins) and long-term effects.