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AD is a common neurodegenerative condition that results in a range of profoundly disabling cognitive, affective, and behavioral symptoms. It affects approximately 5.8 million Americans. Barring significant clinical efforts and medical breakthroughs that prevent or slow disease development, current estimates suggest that by 2050, AD will afflict 14 million patients in the United States. PCPs are on the front lines of early diagnosis of AD, yet many say they feel unprepared and their community lacks adequate specialists in this area. Signs and symptoms of mild cognitive impairment (MCI) and even early AD are often conflated with normal aging, leading to late or missed diagnosis. This is compounded by the lack of a sense of urgency for early, accurate diagnosis because there are no disease-modifying therapies to treat MCI or AD. This eHealth Source activity reviews the pathophysiology of AD, early signs and symptoms, diagnosis first steps, referral patterns, more-complex diagnostic procedures, and existing nonpharmacologic and pharmacologic management strategies. Drs Cohen and Turner provide expert insight into how PCPs can tailor their practice to better care for these patients.
Just days after turning fifty, Martha Maddux, a spirited mother and civic activist, was told she had Alzheimer’s disease. She and husband Carlen felt as though they’d been shoved out of a plane 10,000 feet up, with nothing to grab but themselves. A Path Revealed is not about the fallout from an insidious disease that extended over seventeen years. It is the story of a path of hope emerging during the darkest hours - a path that lifted Carlen and Martha above the devastating symptoms of this disease. Carlen traveled with Martha to the backwoods of Kentucky, where the quiet presence of a Catholic nun revealed a hidden path. He was forced to slow down as he traced this path halfway around the world to Australia, retreated weekends to a monastery, embraced meditation, and landed all alone in Thomas Merton’s cabin. This story conveys a message of hope and joy in the midst of an almost overwhelming tragedy.
Working from the intriguing hypothesis that Alzheimer's dementia is the result of a renegade protein-beta amyloid-Tanzi and others set out to find the gene responsible for its production. Decoding Darkness takes us deep into the minds and far-flung labs of many a prominent researcher, offering an intimate view of the high stakes of molecular genetics, the revolution that propels it, the obstacles that threaten to derail it, and the families whose lives are so dependent upon it. Tanzi and Parson ultimately reveal that Alzheimer's, like heart disease, may be effectively treated-even prevented.
A renowned geriatrician shares tips on how families and individuals can live happy, engaged lives after a dementia diagnosis.
Alzheimer's Disease can be prevented! Alzheimer's Disease can be stopped! Alzheimer's Disease can be reversed! These are the messages of hope Christine Baum VanRyzin brings to you. Christine shares the path she took to find survival, when while still taking part in her mother's homecare, she too, developed similar symptoms with physical and mental losses. Alzheimer's Averted is filled with research and Christine's personal findings and success in the healing process.
Research-based advice for people who care for someone with dementia Nearly half of U.S. citizens over the age of 85 are suffering from some kind of dementia and require care. Loving Someone Who Has Dementia is a new kind of caregiving book. It's not about the usual techniques, but about how to manage on-going stress and grief. The book is for caregivers, family members, friends, neighbors as well as educators and professionals—anyone touched by the epidemic of dementia. Dr. Boss helps caregivers find hope in "ambiguous loss"—having a loved one both here and not here, physically present but psychologically absent. Outlines seven guidelines to stay resilient while caring for someone who has dementia Discusses the meaning of relationships with individuals who are cognitively impaired and no longer as they used to be Offers approaches to understand and cope with the emotional strain of care-giving Boss's book builds on research and clinical experience, yet the material is presented as a conversation. She shows you a way to embrace rather than resist the ambiguity in your relationship with someone who has dementia.
Provides a definitive overview of the complex ecosystem facilitating Alzheimer's Disease drug research and development. Demonstrates a drug's journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.
Alzheimer's disease has received growing attention in recent years because the affected population is growing quickly as life spans in America creep ever upward. As they near retirement, many Americans start to fear that any minor memory lapse-misplacing the keys or forgetting a name-might spell Alzheimer's. In reality such incidents are a normal part of the aging process. In Alzheimer's disease, such incidents progress to a point at which they interfere with normal daily activities on a regular basis, and memory loss becomes progressively more disabling. This book is written for anyone interested in learning more about Alzheimer's disease-people who have it, their families and caregivers, professionals who serve such people, teachers, and anyone with a general interest in the disease. An important feature of this book is clear explanation of the basic biology of the disease. Here is information about who gets the disease, how it is diagnosed, and what happens to people who have it. A large section is devoted to the subject of caring for affected individuals, including legal and financial planning advice and pointers for finding outside support services. Existing treatments are discussed along with suggestions for handling many symptoms without drugs. Understanding Alzheimer's Disease describes the most current knowledge of how and why it arises and gives information about the many avenues being explored in search of a cure. With its chapters on causes and on the search for treatments, this guide will be of interest to a wider section of the population than other books on the disease.
Neuroprotection in Alzheimer’s Disease offers a translational point-of-view from both basic and clinical standpoints, putting it on the cusp for further clinical development with its emphasis on nerve cell protection, including the accumulation of knowledge from failed clinical trials and new advances in disease management. This book brings together the latest findings, both basic, and clinical, under the same cover, making it easy for the reader to obtain a complete overview of the state-of-the-field and beyond. Alzheimer's disease is the most common form of dementia, accounting for 60 to 80 percent of dementia cases. It is a progressive brain disease that slowly destroys memory, thinking skills, and eventually, even the ability to carry out the simplest tasks. It is characterized by death of synapses coupled to death nerve cells and brain degeneration which is manifested by loss of cognitive abilities. Understanding neuroprotection in Alzheimer’s disease will pave the path to better disease management and novel therapeutics. Comprehensive reference detailing neuroprotection in Alzheimer’s Disease, with details on nerve cell protection and new advances in disease management Combines the knowledge and points-of-view of both medical doctors and basic scientists, putting the subject at the forefront for further clinical development Edited by one of the leading researchers in Alzheimer’s Disease
"Is peace possible?" How will you cope with caring for a loved one with Alzheimer's? This book will show you several simple strategies-stepping stones-that can help you find your path to peace as you care for a parent, family member or friend with this illness. Traveling with a loved one through Alzheimer's can be a gift in your life-if you choose to see it this way. You will discover how, by asking the following questions of yourself and others, you can thrive despite the overwhelming obstacles presented by a devastating illness such as Alzheimer's: Who can I turn to for information and support? How do I prepare myself for this journey? How can I stay open to the gifts this experience has to offer?