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Cholangiocarcinoma (bile duct cancer) is a cancer of the bile duct and liver. A person can seem healthy and/or can have a variety of symptoms, such as weight loss, bloating, abdominal pain, jaundice (yellowing of the skin and/or eyes), itchy skin, dark urine and/or pale stools. The location of the tumor within the liver/bile duct and its size and spread to other areas of the body will determine the cancer treatment plan. Treatment options may include surgery, chemotherapy, radiotherapy, liver transplant, targeted therapies and clinical trials. This book aims to help patients understand their options, enabling informed decisions, in conjunction with their doctor and other members of the medical team, about their cancer treatment. Table of Contents: • Understanding cholangiocarcinoma • How does cholangiocarcinoma develop? • Symptoms • Seeing your doctor • Diagnostic tests and procedures • Staging • Biomarker testing • Multidisciplinary teams and tumor boards • Surgery • Radiation therapy • Systemic therapy • Treatments and schedules • Infusion therapy • Clinical trials • What new treatments are being studied? • Targeted treatments • Taking part in research • Palliative procedures • Stents • Reducing side effects • Follow-up care • Outlook • If treatment is unsuccessful • Coping • Being supported • What can I do to help myself?
Inflammatory bowel disease (IBD) is in fact two long-term conditions – ulcerative colitis or Crohn’s disease – that cause problems in the digestive system. No two patients with IBD have the same experience. How the disease progresses, the type of complications and the response to treatment all differ from person to person. The information in this booklet is designed to help you and your family better understand your IBD, its treatment and how you can help yourself. With simple clear illustrations, explanation of medical terms and space to write down the questions you want to ask your doctor or nurse, this resource will help you take control of your condition.
Cholangiocarcinomas (CCAs) are a group of heterogeneous tumors that have traditionally had poor prognosis. Despite being rare, the global incidence of CCA has increased dramatically over the last few decades. However, alongside this, there have been advancements in our understanding, diagnosis and treatment, improving the overall survival and quality of life of patients with advanced disease. This compact yet comprehensive review of CCA serves as a guide for physicians, oncologists, allied health professionals, scientists, patients and caregivers to update their knowledge of the most recent clinical developments and most promising areas of research. Table of Contents: • Pathophysiology, etiology and epidemiology • Diagnosis • Biliary drainage and supportive care • Surgical resection and transplantation • Translational research • Systemic therapy • Immunotherapy • Radiotherapy and photodynamic therapy
100 Questions & Answers About Cholangiocarcinoma, Gallbladder, and Bile Duct Cancers is a resource that empowers patients and caregivers with the information needed to navigate their treatment with realistic goals for a good quality of life and targeted long-term survivorship.
Identifying tumor-specific molecular aberrations via molecular profiling is vital for the use of targeted therapies. Understanding a patient’s unique tumor genetics provides predictive and prognostic information that enables a personalized care plan to be put in place, improving outcomes and minimizing ineffective treatments. 'Fast Facts: Molecular Profiling in Solid Tumors' provides a firm knowledge foundation of somatic molecular profiling methodologies, key information to help with the use of molecular profiling in daily practice and advice on communicating with patients about molecular testing and results. Table of Contents: • Molecular profiling: the basics • Rationale for testing • Sample collection • Test selection and process • Interpreting the report • Talking to patients • Challenges and opportunities
This book provides a comprehensive, state-of-the-art overview of cholangiocarcinoma (CCA). The text is structured to effectively present a broad yet concise overview of bile duct cancer, its relevant definitions, classification schemata, clinical management tenets, translational (including molecular and cellular) facets, and future directions. The book features numerous high-yield illustrations and is authored by an eclectic range of renowned experts in various areas of CCA, reflecting the multidisciplinary nature of the field. Filling a critical gap in the field, Diagnosis and Management of Cholangiocarcinoma: A Multidisciplinary Approach is a valuable resource for clinicians and practitioners who treat patients with bile duct cancer.
Some people suffer from chronic, debilitating disorders for which no conventional treatment brings relief. Can marijuana ease their symptoms? Would it be breaking the law to turn to marijuana as a medication? There are few sources of objective, scientifically sound advice for people in this situation. Most books about marijuana and medicine attempt to promote the views of advocates or opponents. To fill the gap between these extremes, authors Alison Mack and Janet Joy have extracted critical findings from a recent Institute of Medicine study on this important issue, interpreting them for a general audience. Marijuana As Medicine? provides patientsâ€"as well as the people who care for themâ€"with a foundation for making decisions about their own health care. This empowering volume examines several key points, including: Whether marijuana can relieve a variety of symptoms, including pain, muscle spasticity, nausea, and appetite loss. The dangers of smoking marijuana, as well as the effects of its active chemical components on the immune system and on psychological health. The potential use of marijuana-based medications on symptoms of AIDS, cancer, multiple sclerosis, and several other specific disorders, in comparison with existing treatments. Marijuana As Medicine? introduces readers to the active compounds in marijuana. These include the principal ingredient in Marinol, a legal medication. The authors also discuss the prospects for developing other drugs derived from marijuana's active ingredients. In addition to providing an up-to-date review of the science behind the medical marijuana debate, Mack and Joy also answer common questions about the legal status of marijuana, explaining the conflict between state and federal law regarding its medical use. Intended primarily as an aid to patients and caregivers, this book objectively presents critical information so that it can be used to make responsible health care decisions. Marijuana As Medicine? will also be a valuable resource for policymakers, health care providers, patient counselors, medical faculty and studentsâ€"in short, anyone who wants to learn more about this important issue.
Fills a gap in information for frontline professionals caring for GI and Liver patients The only resource of its kind, this is a concise, practical guide to GI and Liver Disease that delivers current information on diagnosing, managing, andtreating common GI and liver disorders, along with liver transplant guidelines. Written for nurses, nurse practitioners, and physician assistants in variedspecialties, it fills a gap in information needed by primary and acute care professionals who are the chief caretakers for GI and liver patients. Thisguide delivers recent important treatment advances that have revolutionized GI and liver care, and provides guidance for seeking expert advice orurgent/emergent care for more complex cases. An outstanding feature is the prominently displayed Fast Facts in a Nutshell highlighting key takeawaypoints at a glance. The resource reviews common GI symptoms and disorders from irritable bowel disorders (including key differences between Crohn's disease and ulcerativecolitis) to gallstones and GERD. A section on liver disease describes essential liver functions, reviews liver function tests, and addresses commonly andless commonly seen liver disease diagnoses. Complications of cirrhosis are examined to assure prompt recognition of these potentially deadly symptoms.Additionally, the book addresses liver transplantation with comprehensive attention to the evaluation process, organ donation/allocation, andpost-transplant care for donor and recipient alike. Each chapter includes an overview, significant laboratory or imaging findings, treatment options,expected outcomes, and Fast Facts in a Nutshell An additional feature is the provision of IDC-10 codes for billing and reimbursement. Key Features: Provides speedy access to current information on diagnosing managing, and treating common GI and liver disorders for front-line professionals Includes comprehensive review of the liver, abnormal liver function tests (LFTs), and transplantation Reflects up-to date information on the latest treatment guidelines for gastrointestinal and liver disease, including celiac disease and Hepatitis C Addresses common gastrointestinal diseases and guidelines for treatment as outlined by ACG Discusses current liver disease management and guidelines for treatment as outlined by AASLD
Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but also to internists, nephrologists, intensive care physicians, and transplant surgeons.
Patient Derived Tumor Xenograft Models: Promise, Potential and Practice offers guidance on how to conduct PDX modeling and trials, including how to know when these models are appropriate for use, and how the data should be interpreted through the selection of immunodeficient strains. In addition, proper methodologies suitable for growing different type of tumors, acquisition of pathology, genomic and other data about the tumor, potential pitfalls, and confounding background pathologies that occur in these models are also included, as is a discussion of the facilities and infrastructure required to operate a PDX laboratory.