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The main question explored by the book is: How can cross-border access to human genetic resources, such as blood or DNA samples, be governed in such a way as to achieve equity for vulnerable populations in developing countries? The book situates the field of genomic and genetic research within global health and research frameworks, describing the concerns that have been raised about the potential unfairness in exchanges during recent decades. Access to and sharing in the benefits of human biological resources are aspects not regulated by any international legal framework such as the Convention on Biological Diversity, which applies only to the exchange of plants, animals and microorganisms, as well as to associated traditional knowledge. Examples of genetic research perceived as exploitative are provided in order to illustrate the legal vacuum concerning the global governance of human genetic resources. The main conclusions drawn from the legal and ethical analysis are: • Benefit sharing is crucial in order to avoid the exploitation of developing countries in human genetic research. • With functioning research ethics committees, undue inducement is less of a concern in genetic research than in other areas of medical research (e.g. clinical trials). • Concerns remain over research involving indigenous populations; accordingly, recommendations are provided. In drawing these conclusions, the book addresses in detail a highly pressing topic in global bioethics and international law. In this regard, it combines bioethical arguments with jurisprudence, in particular with reference to the law of equity and the legal concepts of duress (coercion), unconscionable dealing, and undue inducement.
Equitable Access to High-Cost Pharmaceuticals seeks to aid the development and implementation of equitable public health policies by pharmaco-economics professionals, health economists, and policymakers. With detailed country-by country analysis of policy and regulation, the Work compares and contrasts national healthcare systems to support researchers and practitioners identify optimal healthcare policy solutions. The Work incorporates chapters on global regulatory changes, health technology assessment guidelines, and competitive effectiveness research recommendations from international bodies such as the OECD or the EU. Novel policies such as horizon scanning, managed-entry agreement and post-launch monitoring are considered in detail. The Work also thoroughly reviews novel pharmaceuticals with particular research interest, including cancer drugs, orphan medicines, Hep C, and personalized medicines. - Evaluates impact and efficacy of current access policies and pricing regulation of high-cost drugs - Incorporates existing guidelines and recommendations by international organizations - Compares and contrasts how different countries fund and police high-cost drug access - Explores novel and emergent policies, including managed entry agreement, analysis of real world data and differential pricing - Reviews novel pharmaceuticals of current research interest
As the first of its kind, this handbook presents state-of-the-art information and analysis concerning the state of affairs in bioethics in around 40 countries. The country reports point out the most important discussions as well as the emerging topics in the field. Readers can orientate themselves quickly with regard to the various relevant issues, institutional structures and expertise available in these countries. The authorship of this reference work is truly global as it involves contributions from the best authors with innate knowledge of the bioethics situation in these countries.
In the United States, some populations suffer from far greater disparities in health than others. Those disparities are caused not only by fundamental differences in health status across segments of the population, but also because of inequities in factors that impact health status, so-called determinants of health. Only part of an individual's health status depends on his or her behavior and choice; community-wide problems like poverty, unemployment, poor education, inadequate housing, poor public transportation, interpersonal violence, and decaying neighborhoods also contribute to health inequities, as well as the historic and ongoing interplay of structures, policies, and norms that shape lives. When these factors are not optimal in a community, it does not mean they are intractable: such inequities can be mitigated by social policies that can shape health in powerful ways. Communities in Action: Pathways to Health Equity seeks to delineate the causes of and the solutions to health inequities in the United States. This report focuses on what communities can do to promote health equity, what actions are needed by the many and varied stakeholders that are part of communities or support them, as well as the root causes and structural barriers that need to be overcome.
If humankind were given a mandate to do everything in our power to undermine the earth's functioning, we could hardly do a better job than we have in the past thirty years on the world's oceans, both by what we are putting into it-millions of tons of trash and toxic materials-and by what we are taking out of it-millions of tons of wildlife. Yet only recently have we begun to understand the scale of those impacts. Defying Ocean's End is the result of an unprecedented effort among the world's largest environmental organizations, scientists, the business community, media, and international governments to address these marine issues. In June 2003, in the culmination of a year-long effort, they met specifically to develop a comprehensive and achievable agenda to reverse the decline in health of the world's oceans. As conservation organizations begin to expand their focus from land issues to include a major focus on preservation of the sea, it is increasingly apparent that we have to approach marine conservation differently and at much larger scale than we have to date. What's also clear is the magnitude and immediacy of the growing ocean concerns are such that no one organization can handle the job alone. Defying Ocean's End is a bold step in bringing the resources needed to bear on this vast problem before it is too late. It offers a broad strategy, a practical plan with priorities and costs, aimed at mobilizing the forces needed to bring about a "sea change" of favorable attitudes, actions, and outcomes for the oceans-and for all of us.
The International Treaty on Plant Genetic Resources for Food and Agriculture (ITPGRFA) is a pivotal piece of recent legislation, providing a route map for the use of such resources for sustainable agriculture and food security. Plant Genetic Resources and Food Security explains clearly the different interests and views at stake between all players in the global food chain. It touches upon many issues such as international food governance and policy, economic aspects of food and seed trade, conservation and sustainable use of food and agricultural biodiversity, hunger alleviation, ecological concerns, consumers' protection, fairness and equity between nations and generations, plant breeding techniques and socio-economic benefits related to food local economies. The book shows that despite the conflicting interests at stake, players managed to come to an agreement on food and agriculture for the sake of food security and hunger alleviation in the world. Published with the Food and Agriculture Organization (FAO) of the United Nations and with Bioversity International.
Human wellbeing depends on the capacity of the earth’s natural systems to provide ecosystem goods and services. However, the Millennium Ecosystem Assessment chillingly concludes that unless we take action to mitigate the current decline in ecosystem services, the cost to society will be substantial. In this publication, IUCN defines three key challenges that will need to be addressed in the near future in order to deliver internationally-agreed development goals. Actions for implementation for all three challenges are also proposed, as well as some 'First Steps’ that should be initiated now if we are to secure our future.
This collection explores this balance and the extent to which human rights standards can influence the interpretation of IP norms, for example in defining the scope of IPRs."--BOOK JACKET.
Over the past years, few African countries have been the focus of discussions and analyses generating a vast array of literature as much as Zimbabwe. The socioeconomic and political crises since the turn of the century have deeply transformed the country from the ideals of a vibrant freshly independent nation just two decades earlier. These transformations have necessitated the call for the restructuring of Zimbabwean society, polity, and economy. But this literature remains exclusively within the realm of academic thinking and theorising, with no concerted effort to move beyond this by explicitly drawing out the policy implications. Beyond the Crises: Zimbabwe's Prospects for Transformation is a welcome addition to the academic and policy literature with a much broader and all-embracing focus in terms of policy interventions. By focusing on different aspects of social and economic justice, Murisa and Chikweche go beyond initiating a broad discussion on these two key pillars of human development with a view to suggesting possible future directions of practical solutions and policy development for the attainment of inclusive social and economic justice for Zimbabweans.